Clinical trials: Knee Osteoarthristis
Knee Osteoarthristis
Medication vs. Meditation for Chronic Knee Osteoarthritis
The purpose of this research study is to improve pain management for individuals with chronic knee osteoarthritis pain. Specifically, we are comparing the effects of a mindfulness meditation practice with those of oral…
- Trial name
- NCT07837284
- Testing
- Oral diclofenac potassium 50 mg, Mindfulness meditation
- Volunteers
- 30 people
- Sponsor
- Florida State University
Knee Osteoarthristis, Gonarthrosis
Different Ozone Concentrations for Knee Osteoarthritis
Knee osteoarthritis is a common condition that causes pain, stiffness, and difficulty with daily activities. Ozone injection therapy is a minimally invasive treatment that has been increasingly used to relieve symptoms in people…
- Trial name
- NCT07662512
- Testing
- ozone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Sakarya University
Total Knee Arthroplasty, Knee Osteoarthristis
Application of Perinatal Derivatives in Total Knee Arthroplasty
This pilot study investigators whether the use of perinatal derivatives during knee replacement, in the form of an injection around the joint and patch over the knee joint incision, improves patient outcomes (including…
- Trial name
- NCT07908342
- Testing
- Intraoperative application of CTM Flow and CTM Thick, Total knee arthroplasty (TKA)
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Knee Osteoarthristis
Acute Effects of Two Neoprene Knee Sleeves
This study aimed to evaluate the immediate effects of two different types of elastic neoprene knee sleeves on balance and pain in patients with knee osteoarthritis (KOA).
- Trial name
- NCT06813716
- Testing
- Neoprene elastic knee sleeve, Neoprene elastic knee sleeve with metal supports
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Eskisehir Osmangazi University
Knee Osteoarthristis
ArtiBest for Knee Osteoarthritis
The goal of this clinical trial is to evaluate the real-world effectiveness and safety of ArtiBest in the treatment of knee osteoarthritis. The main questions it aims to answer are: 1.
- Trial name
- NCT06994546
- Testing
- ArtiBest ® Intra articular Injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Maxigen Biotech Inc.
Knee Osteoarthristis
A Study to Investigate the Effectiveness, Safety, and Tolerability of MAG200 Solution for Intra-articular Injection Compared With Placebo in Participants Aged 35 to 75 Years of Age With Symptomatic Osteoarthritis of the Knee.
The purpose of this study is to confirm whether MAG200 (20M or 100M) will improve pain and function of participants with osteoarthritis of the knee compared with placebo. In addition, the two strengths of MAG200 will be compared.
- Trial name
- nexcell-OAK (NCT07106229)
- Testing
- allogeneic human adipose-derived mesenchymal stem cells
- Volunteers
- 573 people
- Sponsor
- Magellan Stem Cells
Knee Osteoarthristis, Obesity & Overweight
E-Health Lifestyle Intervention for Arthritis: A Pilot RCT on Feasibility
Knee osteoarthritis and obesity are common health problems in Hong Kong, especially among South Asian communities, where obesity rates are much higher than the general population.
- Trial name
- CHALAANE (NCT07786038)
- Testing
- Digital Health Intervention, Inactivated Smartband for Activity Monitoring
- Where
- 2 sites in Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Knee Osteoarthristis
Combination of Platelets Rich Plasma and Hyaluronic is an Effective Tool for Treatment of Knee Osteoarthritis
The purpose of the study is to determine the effects of HA, PRP and the combination of HA and PRP in reducing pain and improving functional disability in patients with knee osteoarthritis.
- Trial name
- NCT07089446
- Testing
- Hyaluronic Acid (HA), Platelet Rich Plasma, Hyaluronic Acid (HA) and Platelet rich plasma
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Karachi
Knee Osteoarthristis
Wearable Device Guided Exercise for Patients on Total Knee Arthroplasty Wait-list
Total knee arthroplasty (TKA) is a cost effective solution for people with end-stage knee osteoarthritis. Given Hong Kong's large senior population and age as the primary risk factor for osteoarthritis, waiting times for total…
- Trial name
- NCT07912333
- Testing
- Wearable Device, Control
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- Chinese University of Hong Kong
Inflammatory Articular Diseases, Knee Osteoarthristis
"Transarterial Microembolization (TAME) in Inflammatory Knee Pathology"
Patients with knee OA and chronic pain refractory to at least 3 months of conventional conservative therapy will be included in the study, which will evaluate the clinical results obtained after treatment with selective arterial…
- Trial name
- TAME-OA (NCT07140367)
- Testing
- Transarterial Microembolization
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Osteoarthristis, Knee Replacement Arthroplasty
Comparing Articular Noise and Its Perception Between Two Different Types of Total Knee Arthroplasty
Some patients complain of articular noise (such as clicking, snapping, cracking or popping) after a total knee replacement. Controversy remains about whether there is a correlation between articular noise and worse outcomes…
- Conditions
- Knee Osteoarthristis, Knee Replacement Arthroplasty, Knee Replacement, Total
- Trial name
- NATKA (NCT06880497)
- Testing
- total knee arthroplasty
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Elsan
Knee Arthroplasty, Total, Knee Osteoarthristis
Knee Body Perception and Pain After Total Knee Arthroplasty
This observational study aims to better understand how knee pain and knee-specific body perception are related over time after total knee arthroplasty (knee replacement) for knee osteoarthritis.
- Trial name
- NCT07410884
- Where
- Japan
- Volunteers
- 285 people
- Sponsor
- Prefectural University of Hiroshima
Knee Osteoarthristis
New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?
Total knee replacement is a common surgery for patients with severe knee arthritis. To improve surgical accuracy, surgeons now use robotic systems to help plan and perform the procedure.
- Trial name
- CAPTAIN (NCT07777757)
- Testing
- Attune Total Knee Implant, Persona Total Knee Implant
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Knee Osteoarthristis
Effect Of Sensory Motor Training Versus Resistance Training Among Individuals With Knee Osteoarthritis.
This study aims to address this gap by comparing the effects of sensory-motor training versus resistance training on pain, balance and functional activities, specifically in patients with early-stage knee osteoarthritis.
- Trial name
- NCT07262931
- Testing
- Sensory motor training, Resistance Training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Knee Osteoarthristis, Total Knee Replacement
Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement
This study evaluates the feasibility of a short-term, digitally supported prehabilitation program for patients scheduled for elective total knee replacement (TKR).
- Trial name
- P2R-KneeTEP (NCT07621666)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Usual Care Group
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
Knee Osteoarthristis, Hip Osteoarthritis
Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions
Clinical validation of SMARTDIAGO, an artificial intelligence-based system for remote functional assessment of patients with musculoskeletal disorders and functional frailty.
- Conditions
- Knee Osteoarthristis, Hip Osteoarthritis, Spine Disease, Shoulder Disease
- Trial name
- SMARTDIAGO (NCT07880210)
- Testing
- SMARTDIAGO Remote Functional Assessment
- Where
- 2 sites in Chile
- Volunteers
- 350 people
- Sponsor
- University of Chile