Clinical trials: Knee Injuries, Sport Injury
Defect of Articular Cartilage
Comparison of BioCartilage Versus Marrow Stimulating Procedure for Cartilage Defects of the Knee
Subjects will be selected among the investigators' patient population who are already scheduled to receive a marrow stimulating procedure (MSP), with or without the addition of BioCartilage.
- Trial name
- NCT02203071
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Missouri-Columbia
Ligament Knee Injury, Anterior Cruciate Ligament Rupture
Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport
Following reconstruction of the anterior cruciate ligament (ACL), a standardized rehabilitation protocol is carried out by a physiotherapist.
- Trial name
- ORACL-Run (NCT05323474)
- Testing
- Usual rehabilitation, Rehabilitation optimized
- Where
- 8 sites in France, Switzerland
- Volunteers
- 432 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Knee Injuries
Real-time Optimized Biofeedback Utilizing Sport Techniques
This study will identify the most optimal, focused approach for biofeedback in adolescent females at high risk for anterior cruciate ligament (ACL) injury.
- Trial name
- ROBUST (NCT02754700)
- Testing
- Neuromuscular Training, Hip Focused ROBUST Training, Knee Focused ROBUST Training
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- High Point University
Anterior Cruciate Ligament Injuries, Sports Injury
Neuromusculoskeletal Alterations After ACL Injury
This study investigated how anterior cruciate ligament (ACL) injuries affect not only the knee joint but also brain activity, reaction speed, and psychological readiness to return to sports.
- Conditions
- Anterior Cruciate Ligament Injuries, Sports Injury, Neurocognitive Function
- Trial name
- NEURO-ACL (NCT07163468)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Tendinopathy
Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma
Platelet rich plasma has been used in previous studies to stimulate faster healing of torn ligaments and tendons in order to help reduce pain and restore normal function.
- Trial name
- NCT01406821
- Testing
- Ultrasound-guided platelet-rich-plasma (PRP) injection, Ultrasound-guided dry needling
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Aging, Athletic Injuries
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability.
- Conditions
- Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
- Trial name
- NCT05344001
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marquette University
Sport Injury, Sports Physical Therapy
Prediction of Knee Injuries Through System Dynamics Modeling
The large number of studies in the recent decade dealing with knee injury prevention seems not effective enough to cause a decline in knee injury rates.
- Trial name
- NCT05430581
- Where
- Greece
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Patras
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
The Effectıveness Of Structured Myofascial Chain Exercise Training After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction(ACLR) surgery accepts best choices which condicions are totaly ruptured ACL or partial ruputures when patients with high activity level.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05423184
- Testing
- Exercise Therapy For Lower Extremities, Exercise Therapy For Myofascial Chains
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Quadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction
This prospective randomized clinical trial aims to compare quadriceps tendon and peroneus longus tendon autografts in anterior cruciate ligament reconstruction.
- Trial name
- NCT07671729
- Testing
- Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft, Anterior Cruciate Ligament Reconstruction Using Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Sport Injury, Anterior Cruciate Ligament Injury
Definition of Biomechanical Indices Measurable During Sport Movements for the Prevention of Primary and Secondary ACL Injury
The aim of the study is to define a set of quantitative parameters related to articular biomechanics, which will be evaluated during some specific motor tasks.
- Conditions
- Sport Injury, Anterior Cruciate Ligament Injury, Biomechanical; Lesion
- Trial name
- BIOS-ACL (NCT03840551)
- Testing
- Biomechanical analysis with inertial sensors (XSENS) and motion capture (BTS)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injury
Maximum Oxygen Uptake in ACL-injured Professional Soccer Players
Our purpose is to evaluate maximum oxygen uptake (VO2max) in ACL-injured professional soccer players and after a six-month period of post-operative rehabilitation, compared to a control group of healthy professional soccer…
- Trial name
- NCT02674282
- Testing
- ACL reconstruction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ACL Injury, Meniscus Lesion
Muscle Function and Traumatic Knee Injury in Sports
The aims of the project are to 1) evaluate different aspects of muscle function and its role as a potential risk and/or protective factor for traumatic knee injury in youth female athletes; 2) develop and evaluate a battery of…
- Conditions
- ACL Injury, Meniscus Lesion, Cartilage Injury, Ligament Injury
- Trial name
- NCT03479775
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University
Anterior Cruciate Ligament Injury
Back in the Game: a Smartphone Application to Support Athletes Returning to Sport After Serious Injury
Returning to sport is one of the primary concerns of athletes following injury. Yet, after serious injury, up to 50% of athletes do not return to competitive sport.
- Trial name
- BANG (NCT03959215)
- Testing
- Back in the Game, Usual rehabilitation care
- Where
- 7 sites in Sweden
- Volunteers
- 169 people
- Sponsor
- Karolinska Institutet
Osteoarthritis, Knee, Cruciate Ligament Injury
Basic Research Projects Related to Sports Injuries
Biological samples are important human genetic resources, which can provide great value for medical research, and how to protect and rationally utilize them is of great importance.However, at present, the blood samples after…
- Conditions
- Osteoarthritis, Knee, Cruciate Ligament Injury, Patella Dislocation, Discoid Meniscus of Knee
- Trial name
- NCT04958551
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Rupture of Anterior Cruciate Ligament, Complete Tear, Knee, Anterior Cruciate Ligament
Comparison of Dynamic Knee Stability and Functional Outcomes in Anatomical ACL Reconstruction at AM or Central Position
This is a prospective, randomized and double-blind clinical trial about anatomical single-bundle anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT02074917
- Testing
- Anatomical ACL reconstruction
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Injury Leg, Back Pain
Assessment of Effectiveness of Neuromuscular Training in Treatment of Lumbar Spine in Football Players
The project aims to assess the effectiveness of neuromuscular training according to the concept of Kinetic Control (KC) in prevention and treatment of lumbar spine and knee pain and in reduction of risk of injury in female…
- Conditions
- Injury Leg, Back Pain, Sport Injury, Training Group, Sensitivity
- Trial name
- NCT04134741
- Testing
- Kinetic Control
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- John Paul II University in Biała Podlaska
Knee Injuries, Sport Injury, Knee Injuries
Effects of Mulligan Mobilization With Movement Versus Kinesiotaping and Placebo on Knee Function and Injury -Related Outcomes in Basketball Players
This is a randomized RTC study where the KOS-ADLS score of athletes' functionality and the OSTRC score of sports overuse injuries were used as outcomes, which were measured before the start of treatment, 1 hour and 2 weeks after…
- Trial name
- Sport _MWM_RTC (NCT07510243)
- Testing
- Mulligan Mobilization with movement MWM, Kinesiotaping
- Where
- Albania
- Volunteers
- 60 people
- Sponsor
- University Aleksander Moisiu Durres
Knee Ligament Injury
Reference Values for Knee Rotational Amplitudes in a Population of Athletes
Rupture of the anterior cruciate ligament (ACL) is a frequent and disabling injury in pivot sports, leading to knee laxity and instability, reduced performance and an increased risk of early osteoarthritis.
- Trial name
- PRELAX (NCT07013019)
- Testing
- Measures of overall (internal+external) knee rotational amplitudes
- Where
- 2 sites in France
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Anterior Cruciate Ligament Rupture
Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approac
The investigators designed a prospective randomized trial to evaluate whether an app based active muscle training program (GenuSport) can improve the postoperative strength by starting rehabilitation immediately after primary…
- Trial name
- NCT04224376
- Testing
- App based Serious Gaming with the Genu Sport knee trainer
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School