Clinical trials: Knee Cap
Osteoarthritis
Meloxicam SoluMatrix® Capsules vs Meloxicam Tablets to Treat Osteoarthritis Pain
The purpose of this study is to evaluate the safety and efficacy of a low dose and a high dose of Meloxicam SoluMatrix® Capsules versus Meloxicam Tablets for the treatment of pain due to osteoarthritis of the knee or hip.
- Trial name
- NCT02405793
- Testing
- Meloxicam Test Capsules, Meloxicam Tablets
- Sponsor
- Iroko Pharmaceuticals, LLC
Pain Management, Osteoarthritis
Efficacy and Safety of Etoricoxib+Diacerein in Osteoarthritis.
The goal of this clinical trial is to learn if fixed-dose combination etoricoxib 90 mg + diacerein 50 mg capsule works to treat knee/hip osteoarthritis-associated pain in adults. It will also learn about the safety of the drug.
- Trial name
- NCT07549386
- Testing
- Etoricoxib 90 mg + diacerein 50 mg, Meloxicam 15 mg + diacerein 50 mg
- Where
- 4 sites in Mexico
- Volunteers
- 123 people
- Sponsor
- Laboratorios Liomont
Circulatory Disease
Phase II Clinical Study of H001 Capsule in the Prevention of Venous Thromboembolism After Total Knee Arthroplasty
This study is a multicenter, randomized, open-label, positive-controlled Phase II clinical study to evaluate the efficacy and safety of H001 capsules in the prevention of venous thromboembolism (VTE) in subjects undergoing Total…
- Trial name
- NCT06963320
- Testing
- H001 Capsule 200mg-qd, Enoxaparin Sodium Injection, H001 Capsule 300mg-qd
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC
Patellofemoral Osteoarthritis
Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration
The PELICAN study is a prospective, non randomized, dual arm, multi-center clinical study comparing clinical outcomes of subjects treated with the LIFT Implant System to subjects treated with Tibial Tubercle Osteotomy (TTO).
- Trial name
- PELICAN (NCT06423300)
- Testing
- LIFT Implant, Tibial Tubercle Osteotomy
- Where
- 5 sites in United States
- Volunteers
- 245 people
- Sponsor
- ZKR Orthopedics Inc
Osteoarthritis
Study of Meloxicam Capsules in Subjects With Osteoarthritis of the Knee or Hip
The purpose of this study is to evaluate the safety of Meloxicam SoluMatrix Capsules for up to 52 weeks in subjects with pain due to osteoarthritis (OA) of the knee or hip
- Trial name
- NCT01801735
- Testing
- Meloxicam Test Capsules
- Where
- 40 sites in United States
- Volunteers
- 600 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Osteoarthritis of the Knee
ATTUNE Cementless FB Tibial Base Clinical Study
This is a prospective, multi-center, non-randomized, single arm observational study. The primary objective of this clinical investigation is to evaluate functional responder rates with an objective performance criteria (OPC) of…
- Trial name
- NCT04630262
- Testing
- ATTUNE Cementless CR Fixed Bearing, ATTUNE Cementless PS Fixed Bearing
- Where
- 15 sites in United States
- Volunteers
- 80 people
- Sponsor
- DePuy Orthopaedics
Mild to Moderate Knee OA
A Prospective Observational Study to Evaluate Long-term Changes in Cartilage Morphology in Subjects Who Previously Received TPX-100 or Placebo in Study TPX-100-1 for Patellar Osteoarthritis Involving Both Knees
To evaluate the long-term changes in patellar cartilage thickness in TPX-100 versus placebo-treated knees in subjects who participated in Study TPX-100-1 or TPX-100-2.
- Trial name
- NCT03125499
- Testing
- Previous treated with TPX-100
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- OrthoTrophix, Inc
Knee Osteoarthritis
A Study Evaluating the Safety and Efficacy of a Second Course of TPX-100 in Subjects Who Previously Received TPX-100 for Patellar Osteoarthritis Involving Both Knees
The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of a second course of TPX-100 administered by intra-articular injection to subjects with osteoarthritis of the knee who participated in…
- Trial name
- NCT02837900
- Testing
- TPX-100 200 mg 4 times weekly for 4 weeks
- Volunteers
- 14 people
- Sponsor
- OrthoTrophix, Inc
Postoperative Anemia, Arthroplasty, Replacement, Hip
Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia
To assess the safety, tolerability, efficacy, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of orally administered SSS17 capsules in patients with postoperative anemia following elective total hip or knee…
- Conditions
- Postoperative Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT07007936
- Testing
- SSS17 Capsule (6 Dose Levels)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Defect of Articular Cartilage, Knee Injuries
DeNovo NT Natural Tissue Graft Stratified Knee Study
The purpose of this study is to evaluate the long-term relief of pain and return to function for patients receiving DeNovo NT for cartilage lesions in the knee.
- Trial name
- NCT01670617
- Testing
- Particulated Juvenile Articular Cartilage
- Where
- 18 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- Zimmer Orthobiologics, Inc.
Osteoarthritis, Chronic Pain
A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
The purpose of this study is to evaluate the efficacy of Kadian NT (ALO-01) compared with placebo for treating moderate to severe chronic pain over a 12 week period.
- Trial name
- NCT00420992
- Testing
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release)
- Where
- 81 sites in United States
- Volunteers
- 547 people
- Sponsor
- Pfizer
Osteoarthritis, Knee, Osteoarthritis
A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
The goal of this clinical study is to evaluate the effectiveness of the properties that support the functional state of the joints and the safety of the dietary supplement for food ARTNEO®, oral capsules, in patients with stage…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT05975879
- Testing
- undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO)
- Where
- 12 sites in Russia
- Volunteers
- 212 people
- Sponsor
- NPO Petrovax
Cartilage Injury, Cartilage Damage
Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Patella
The purpose of this clinical study is to evaluate the use of ProChondrix Cryopreserved Osteochondral Allograft to obtain evidence of effectiveness, defined as an improvement in physical function and pain, when used on a…
- Trial name
- NCT03873545
- Testing
- Cryopreserved Osteochondral Allograft
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- AlloSource
Knee Osteoarthritis
Evaluation of the Efficacy and Safety of Entelon Tab. 150mg in Patients With Osteoarthritis of Knee
This clinical trial is planned to prove Entelon tab. arm is not inferior to Celebrex cap. arm in terms of the efficacy and safety through the change of K-WOMAC's total score sum in patients with osteoarthritis of knee.
- Trial name
- NCT01768520
- Testing
- Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks, Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks
- Where
- South Korea
- Volunteers
- 338 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Arthroplasty, Replacement, Knee, Thromboembolism
Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement
To determine the comparative efficacy and safety of two different doses (75mg day 1 followed by 150 mg day 2-completion, and 110 mg day 1 followed by 220 mg day 2-completion) of dabigatran administered orally (capsules), compared…
- Trial name
- NCT00152971
- Testing
- Dabigatran Dose 1 - day 2 to completion, Dabigatran Dose 1 - day 1, Dabigatran Dose 2 - day 2 to completion
- Where
- 94 sites in United States, Canada and 2 more
- Volunteers
- 2,615 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis of the Knee
The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee
The purpose of this study is to evaluate efficacy and safety of Imotun capsule in osteoarthritis of the knee
- Trial name
- ABSOLUTE-OS (NCT01743287)
- Testing
- Imotun capsule
- Where
- 10 sites in South Korea
- Volunteers
- 234 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Knee Osteoarthritis
Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis
Previous study showed that Guli capsule could suppress the adjuvant multiple arthritis; have inhibitory effect on carrageenan gelatinous and formaldehyde foot swelling; improve the symptom of osteoporosis patients; and improve…
- Trial name
- NCT02484508
- Testing
- Guli capsule, Kangguzengsheng capsule
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Guizhou Bailing Group Pharmaceutical Co Ltd
Osteoarthritis
Study of Diclofenac Capsules to Treat Osteoarthritis Pain
The purpose of this study is to determine whether Diclofenac [Test] Capsules are safe and effective for the treatment of osteoarthritis pain of the hip or knee.
- Trial name
- NCT01461369
- Testing
- Diclofenac
- Where
- 40 sites in United States
- Volunteers
- 305 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Arthroplasty, Replacement, Knee, Thromboembolism
RE-MODEL Dabigatran Etexilate 150mg or 220mg Once Daily (o.d.) Versus (v.s.) Enoxaparin 40mg o.d. for Prevention of Thrombosis After Knee Surgery
A phase III, randomised, parallel-group, double-blind, active controlled study to investigate the ef ficacy and safety of two different dose regimens of orally administered dabigatran etexilate capsule s [150 or 220 mg once daily…
- Trial name
- NCT00168805
- Testing
- enoxaparin, dabigatran etexilate
- Where
- 105 sites in Australia, Austria and 13 more
- Volunteers
- 2,101 people
- Sponsor
- Boehringer Ingelheim