Clinical trials: Kidney Stone
Healthy
Renal Metabolism of Glycolate to Oxalate
This study will determine the contribution of glycolate metabolism to urinary oxalate excretion in healthy subjects, using carbon 13 isotope glycolate tracer technique and a low-oxalate controlled diet.
- Trial name
- NCT04437225
- Testing
- Low oxalate controlled Diet, Primed, continuous intravenous infusion of 13C2-Glycolate, Bolus intravenous infusion of 13C2-Glycolate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Renal Calculi
Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure
This study evaluates the safety and efficacy of the suctioning flexible ureteroscopy(SF-URS) with automatic control of renal pelvic pressure for the treatment of upper urinary calculi using a prospective, randomized design.
- Trial name
- NCT02734914
- Testing
- SF-URS with automatic control of RPP, conventional F-URS
- Volunteers
- 60 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Urolithiasis, UTI
Antibiotic Prophylaxis With Routine Ureteral Stent Removal
This study will be a single-institutional randomized, single-blinded prospectively controlled clinical trial of a single dose of Ciprofloxicin 500mg antibiotic tablet as prophylaxis at the time of office flexible cystoscopy with…
- Trial name
- STENTABX (NCT02944825)
- Testing
- Ciprofloxacin, trimethoprim/sulfamethoxazole, No Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Thulium Fiber Laser, Fans
Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study
The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time.
- Conditions
- Thulium Fiber Laser, Fans, Lithotripsy, Laser, Renal Stone
- Trial name
- NCT07639385
- Testing
- Dusting, Fragmentation
- Volunteers
- 86 people
- Sponsor
- Bir Hospital
Kidney Stone, Ureteric Stone
Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg
Ureteral stenting is a common urological procedure performed to relieve obstruction and facilitate urinary drainage. Despite its effectiveness, stent-related symptoms (SRS) such as dysuria, frequency, urgency, flank pain, and…
- Trial name
- NCT07562282
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Urolithiasis, Stones, Kidney
Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence Study
The goal of this clinical trial is to evaluate the effectiveness and safety of Steerable Ureteroscopic Renal Evacuation (SURE) with the CVAC System versus other commonly used renal-stone interventions.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- SCORE (NCT07155005)
- Testing
- CVAC® SYSTEM, FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS), DIRECT IN-SCOPE SUCTION (DISS) IN FLEXIBLE URETEROSCOPY (FURS)
- Volunteers
- 1,000 people
- Sponsor
- Calyxo, Inc.
Nephrolithotomy, Percutaneous, Kidney Stone
The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL
To analyze and compare the puncture success rate, puncture fluoroscopy time and intraoperative puncture complications of two different puncture techniques; fluoroscopic bi-planar (0-30º) versus newly reported bi-planar (0-90º)…
- Conditions
- Nephrolithotomy, Percutaneous, Kidney Stone, PCNL
- Trial name
- NCT04557722
- Testing
- 0-30° Biplanar Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy, New 0-90° Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Urolithiasis
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study
Many things, like not drinking enough fluids, contribute to making kidney stones and there is also a genetic tendency. We looked into this in 1998-2000 in 14 families with several stone-formers.
- Trial name
- NCT06211842
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Kidney Calculi
ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi
The purpose of this study is to measure how well two different devices work to break up and remove kidney stones. We are comparing a newer device to an older one to see which one is faster at breaking up kidney stones.
- Trial name
- NCT03959683
- Testing
- Trilogy Lithotrite, The ShockPulse-SE Lithotripsy System
- Where
- 4 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Indiana University
Urolithiasis, Kidney Stones
Pain Control During ESWL Using Non-Opioid Analgesics
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL).
- Conditions
- Urolithiasis, Kidney Stones, Ureteral Stones
- Trial name
- ESWL-PAIN (NCT07512297)
- Testing
- Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- University of Gaziantep
Nephrolithiasis of Both Kidneys
Bilateral Percutaneous Nephrolithomy
The purpose of this study is to determine the effective regimen for definitive surgical therapy of bilateral kidney stones. It is unknown whether patients who undergo simultaneous bilateral percutaneous nephrolithotomy (PCNL)…
- Trial name
- NCT03924362
- Testing
- PCNL
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Kidney Stone, Kidney Calculi
Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones.
The aim of this study is to evaluate and assess the outcomes of flexible ureteroscopy (FURS) with flexible and navigable suction UAS (FANS) in the treatment of lower calyceal stones.
- Trial name
- NCT07238803
- Testing
- flexible and navigable suction sheath with flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Zagazig University
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Kidney Stone, Normal Controls
Oxalate and Citrate
This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.
- Trial name
- NCT05334979
- Testing
- Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Calcium Oxalate Urolithiasis
Mineral Water for Prevention of Renal Stones
The investigators would like to assess if the intake of high bicarbonate mineral water would not only increase total fluid intake but will also be able to give patients the additional benefit of correcting the urinary…
- Trial name
- NCT04638166
- Testing
- Mineral water, Plain water
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- Singapore General Hospital
Kidney Stone, Kidney Calculi
Evaluation of Infection in Obstructing Urolithiasis
Obstructing urolithiasis can be life-threatening in the setting of urinary tract infection. The purpose of this study is to identify and validate risk factors and markers for the presence of infection and development of sepsis…
- Conditions
- Kidney Stone, Kidney Calculi, Urinary Tract Obstruction, Infection
- Trial name
- eIOU (NCT04332861)
- Testing
- Initial clinical and laboratory evaluation
- Where
- 2 sites in United States
- Volunteers
- 477 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stone
Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
Tamsulosin (Flowmax)is approved by the FDA for the treatment for enlarged prostate. Several studies regarding the use of Tamsulosin for the treatment of lower kidney stones have been carried out in the non-Emergency Department…
- Trial name
- Flowmax (NCT00762424)
- Testing
- Flowmax
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- WellSpan Health
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Renal Stone
Flexible Mini Percutaneous Nephrolithotomy Vs Retrograde Intra-renal Surgery
The use of flexible ureteroscopy and minimally-invasive percutaneous techniques, which utilize smaller tract sizes, has been established as a way to decrease the invasiveness of procedures and improve patient outcomes compared to…
- Trial name
- NCT06249100
- Testing
- flexible mini percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University