Clinical trials: Ketones
Heart Failure With Reduced Ejection Fraction
Ketone Pharmacokinetic Study in HFrEF
The purpose of this study is to test whether an over-the-counter ketone ester drink is well tolerated in people with heart failure on, and not on, a heart failure medication class called SGLT2 inhibitors.
- Trial name
- NCT05757193
- Testing
- DeltaG (250 mg/kg), DeltaG (500 mg/kg)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Healthy
Effect of an Alpha-linolenic Acid-rich Supplement on Ketogenesis and Plasma Fatty Acids
Background: As the main alternative fuel to glucose for the brain, increased plasma ketones could potentially help compensate for brain glucose hypometabolism occurring during aging.
- Trial name
- NCT02410161
- Testing
- alpha-linolenic acid-rich supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Breast Neoplasm, Metastasis
Monotherapy With Eribulin In Her2 Negative Metastatic Breast Cancer as a First Line Treatment
Multicentre, prospective, non-controlled phase II clinical trial to evaluate the efficacy and tolerability of first line single agent Eribulin in patients with HER2-negative metastatic breast carcinoma (MBC) previously exposed to…
- Trial name
- MERIBEL (NCT02061085)
- Testing
- Eribulin
- Where
- 11 sites in Spain
- Volunteers
- 53 people
- Sponsor
- MedSIR
Ketosis, Type 2 Diabetes
Exogenous Ketones in Type 2 Diabetes
Exogenous ketone supplements are proposed to have glucose-lowering potential, provide an alternative fuel for the brain and to enhance cognitive function.
- Trial name
- NCT04194450
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of British Columbia