Clinical trials: Keratoconjunctivitis Sicca
Sjogren's Syndrome (SS)
An Efficacy and Safety Study of Injectable Ravagalimab to Assess Change in EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI) in Adult Participants With Moderately to Severely Active Primary Sjogren's Syndrome (pSS)
Sjogren's syndrome (SS) is a chronic, multisystem autoimmune disease characterized by lacrimal and salivary gland inflammation, with resultant dryness of the eyes and mouth and occasional glandular enlargement.
- Trial name
- NCT05217472
- Testing
- Ravaglimab, Ravagalimab
- Where
- Netherlands
- Sponsor
- AbbVie
Dry Eye Syndromes
Efficacy and Safety of AJU-S56 in Dry Eye Syndrome Patients
This study is planned to Evaluate the Efficacy and Safety of test drug (AJU-S56) compared to control drug(vehicle) in Patients with Dry Eye Disease.
- Trial name
- NCT06337981
- Testing
- AJU-S56 5%
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- AJU Pharm Co., Ltd.
Dry Eye Disease
Evaluation of Safety and Tolerability of Investigational Ocular Lubricants
The purpose of this study is to evaluate investigational ocular lubricants for their safety and tolerability on subjects with mild to moderate dry eye disease.
- Trial name
- NCT05888519
- Testing
- FID123300 ocular lubricant, FID123301 ocular lubricant, FID122505 ocular lubricant
- Where
- 3 sites in Australia
- Volunteers
- 47 people
- Sponsor
- Alcon Research
Dry Eye Syndromes
A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease
A double-masked, randomized, multi-center, placebo-controlled, parallel-group study in adult patients with Dry Eye Disease (DED). Patients will be randomly assigned to receive either SJP-0035 0.001% or placebo
- Trial name
- NCT03527212
- Testing
- SJP-0035 0.001%
- Where
- 23 sites in United States
- Volunteers
- 329 people
- Sponsor
- Senju Pharmaceutical Co., Ltd.
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Dry Eye Disease
Phase II Study of SHJ002 Sterile Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
The purpose of this study is to measure efficacy and safety with SHJ002 sterile ophthalmic solution compared to vehicle in participants with Dry Eye Disease (DED).
- Trial name
- NCT05486728
- Testing
- SHJ002/Vehicle
- Where
- 4 sites in Australia, Taiwan and 1 more
- Volunteers
- 85 people
- Sponsor
- Dreamhawk Vision Biotech, Inc.
Dry Eye Disease
Study to Evaluate the Efficacy and Safety of CKD-352
The purpose of this study is to compare the efficacy and safety of CKD-352 in patients with dry eye disease
- Trial name
- NCT04548427
- Testing
- CKD-352, Diquafosol Sodium 3%
- Where
- South Korea
- Volunteers
- 283 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Dry Eye
An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye
The primary objective of this study was to assess the efficacy and safety of rhNGF when administered as eye drops to patients with dry eye The secondary objectives of this study were: To assess change from baseline in Symptom…
- Trial name
- NCT03019627
- Testing
- NGF, Vehicle
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Dompé Farmaceutici S.p.A
Dry Eye Syndrome
Systane Clinical Experience Study
To evaluate the physical effect of SYSTANE QID in people that have moderate to severe dry eyes and to establish doctor confidence to prescribe Systane.
- Trial name
- NCT00818909
- Testing
- Systane
- Volunteers
- 941 people
- Sponsor
- Alcon Research
Sjögren's Syndrome
Exosomes in Patients With Ocular Involvement of Sjögren's Syndrome
This study is a single-center, multiple-dosing, prospective, nonrandom, single-arm trial.
- Trial name
- NCT07192666
- Testing
- Exosome Preparation
- Volunteers
- 12 people
- Sponsor
- Guangdong ProCapZoom Biosciences Co., Ltd.
Dry Eye Syndromes
Clinical Study to Investigate the Efficacy and Safety of SJP002 Ophthalmic Solution in Patients With Dry Eye Syndrome.
This study is to evaluate the efficacy and safety of SJP002 ophthalmic solution compared to placebo in patients with Dry Eye Syndrome.
- Trial name
- NCT03723811
- Testing
- SJP002 BID, SJP002 QID
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Samjin Pharmaceutical Co., Ltd.
Evaporative Dry Eye Disease
Evaluation of MAF-1217 in Patients With DED
This is a pre-market, multicentre, double-blind, randomized, crossover, non-inferiority study comparing the efficacy of MAF-1217 and Cationorm® in adult patients with evaporative DED.
- Trial name
- NCT03833882
- Testing
- MAF1217, Cationorm
- Where
- 2 sites in Italy
- Volunteers
- 72 people
- Sponsor
- VISUfarma SpA