Clinical trials: Keloids
Acceptability Study, Real-use Conditions
Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars
Evaluation of the safety and topical efficacy of a scar gel after 90 days of continuous use, comparing it to a benchmark for preventing hypertrophic scars and improving appearance, hydration and pigmentation.
- Conditions
- Acceptability Study, Real-use Conditions, Safety and Efficacy, Topical Administration
- Trial name
- NCT06751433
- Testing
- Scar gel, Scar gel comparator
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Wound Heal, Scar
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions
The pilot study is prospective, randomized, double-blinded, with intra-subject comparisons against a vehicle control. The primary objective of this pilot study is to investigate the safety and effectiveness of a new wound care…
- Conditions
- Wound Heal, Scar, Keloid, Surgical Wound
- Trial name
- NCT04169438
- Testing
- Vehicle Cream Base Emulsion Moisturizer + Petrolatum, FS2 Emulsion Moisturizer + Petrolatum
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Keloid Scars, Hypertrophic Scars
Topical Cryotherapy and Keloid/Hypertrophic Scars
The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of…
- Trial name
- NCT07336368
- Testing
- Cryotherapy with liquid nitrogen, Intralesional Triamcinolone 10 mg/ml
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sonal Choudhary
Keloids
Sorafenib for Patients With Extensive Keloids
Treatment of keloid disorder is an area of unmet medical need. Current treatments for keloid partially address small and localized keloids, yet there are no wholly satisfactory or effective treatments for patients with extensive…
- Trial name
- NCT01425216
- Testing
- Sorafenib
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tirgan, Michael H., M.D.
Wound Healing
Plasma Therapy for Scar Management
This study is a prospective, multicenter, real-world observational study. It aims to evaluate whether adding plasma device therapy to standard scar care is effective and safe for treating various types of scars, including…
- Trial name
- NCT07548593
- Testing
- Plasma Device
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Keloids Scars
The Efficacy of Intralesional Bleomycin as Compared to 5-Flourouracil (5-FU) and Triamcinolone Acetonide (TAC) for the Treatment of Keloids: A Randomized Control Trial.
The goal of this clinical trial is to learn if drug bleomycin intralesionally is beneficial than intralesional 5FU and Triamcinolone Acetonide in treating Keloids.
- Trial name
- NCT07201766
- Testing
- intralesional bleomycin, 5-flourouracil and triamcinolone acetonide
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- King Edward Medical University
Blisters, Second Degree Burns
Evaluation and Comparison of Keloids and Second Degree Burns Blisters Fluid
It is well documented that following thermal burns injury the development of hypertrophic scars and keloid (HSK) ranges between 40 to 90%.
- Conditions
- Blisters, Second Degree Burns, Wounds
- Trial name
- NCT01627769
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Keloid of Ear Lobe
siRNA Microneedle Patches for Ear Keloid Post-Surgical Scars
The goal of this clinical trial is to evaluate whether small interfering RNA (siRNA) microneedle patches can improve the scar appearances of ear keloids treated with surgery.
- Trial name
- SILK (NCT07596628)
- Testing
- Small interfering RNA (siRNA) Microneedle Patches, Carbon Dioxide (CO2) Laser Surgery, Intralesional Triamcinolone 40 mg/mL
- Where
- Singapore
- Volunteers
- 158 people
- Sponsor
- Ong Kim Yao
Burn Scar
Efficacy of Spray Silicone in Alteration of Burn Scar
In a burn population, conduct a prospective, double-blinded, randomized, controlled clinical trial to determine the ability of spray silicone to alter the physical characteristics of burn scar compared to a placebo.
- Trial name
- NCT01075165
- Testing
- silicone spray, saline spray
- Where
- 2 sites in United States
- Sponsor
- United States Army Institute of Surgical Research
Keloid
A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrence
Phase 2, randomized, double-blind, multiple arm, controlled study to evaluate safety \& efficacy of various doses of STP705 in reducing post Keloidectomy keloid recurrence.
- Trial name
- NCT04844840
- Testing
- STP705
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Sirnaomics
Keloid Scar
Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
This is a split-scar study with a target sample size of 20. There are two interventions: fractional erbium:YAG-assisted drug delivery of 5-fluorouracil and fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide.
- Trial name
- NCT04786210
- Testing
- Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Coronary Restenosis, Coronary Stent Occlusion
Restenosis in Coronary Stents And Cutaneous HEaLing
Case control study of patients with and without restenosis to demonstrate the link between in-stent restenosis and an excessive skin healing.
- Conditions
- Coronary Restenosis, Coronary Stent Occlusion, Skin Scarring, Keloid
- Trial name
- RACHEL (NCT04915391)
- Testing
- Skin biopsy and blood sample for inflammation markers, RNA and proteins
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Keloid
Study of Psycho-Social Impact of Keloid
Despite their benign nature, keloids may constitute a severe aesthetic, and in some cases, functional problem which translates to various repercussions on person's quality of life, including much stress and insecurities.
- Trial name
- NCT01478243
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Tirgan, Michael H., M.D.
Keloid
A Randomized Clinical Study Comparing Two Closure Techniques of Excised Keloids
This investigator initiated study, single-blinded, parallel, randomized study will be conducted in subjects with 2 or more keloids similar in size and duration on a similar area of the body.
- Trial name
- NCT00519493
- Testing
- Suture, Clozex
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Hypertrophic Scars, Keloids
CICATRIX in the Treatment of Hypertrophic Scars and Keloids Scars
The purpose of the study is to assess the efficacy of CICATRIX (Asian Gotu Kola or Pennywort) usage in the treatment of Hypertrophic scars and keloids.
- Trial name
- NCT00993005
- Testing
- Cicatrix
- Where
- Cuba
- Volunteers
- 90 people
- Sponsor
- Catalysis SL
Keloid
Outcomes of the A.S.A.P. Algorithm for Keloids: A Controlled Prospective Study
The goal of this clinical trial is to evaluate if the A.S.A.P. algorithm can treat and improve clinical and objective outcomes in patients with keloids.
- Trial name
- NCT07836569
- Testing
- A.S.A.P. Algorithm
- Where
- Brazil
- Volunteers
- 116 people
- Sponsor
- Gisele Viana de Oliveira
Keloid Ear
Pressure Device in the Treatment of Ear Keloids
Keloids are benign cutaneous lesions, arising from proliferating fibroblasts. Keloids of the ear may occur after helix piercings and are difficult to treat, since they tend to form recurrences.
- Trial name
- PRESSURE (NCT02962518)
- Testing
- Pressure Device, Fillet Technique, Triamcinolone
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Ulm
Keloid, Stem Cell
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
The objective of this study is to observe the potency of umbilical cord-derived mesenchymal stem cells (UC-MSC) and umbilical cord-derived conditioned medium (UC-CM), or triamcinolone acetonide (TA) in keloid therapy, measured by…
- Trial name
- NCT05939817
- Testing
- umbilical cord-derived mesenchymal stem cells (UC-MSC), umbilical cord-derived mesenchymal stem cells conditioned medium (UC-CM), Triamcinolone Acetonide (TA)
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Tattoo, Acne Keloidalis Nuchae
7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream
The purpose of this study is to compare the efficacy of 7% lidocaine / 7% tetracaine cream and 2,5% lidocaine / 2,5% prilocaine cream in reducing self-reported pain during a single laser procedure in the treatment of acne…
- Trial name
- OPTICA (NCT02372786)
- Testing
- 2,5% lidocaine / 2,5% prilocaine cream, 7% lidocaine / 7% tetracaine cream, Neodymium-doped yttrium aluminium garnet (Nd:Yag) laser
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Keloid Scar Following Surgery, Scars, Hypertrophic
Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry
Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool…
- Conditions
- Keloid Scar Following Surgery, Scars, Hypertrophic, Scar Keloid
- Trial name
- NCT06806735
- Testing
- 3D-Pictures
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich