Clinical trials: Joint Replacement
Arthritis
S.E.S Shoulder Arthroplasty Data Collection
This observational study intends to collect efficacy and safety data on S.E.S shoulder system
- Trial name
- NCT00754416
- Where
- 12 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Role of Bone in Knee Osteoarthritis (OA)
The purpose of the study is to investigate protein and gene expression among damaged knee tissues. We will perform MRI's on subjects prior to total knee replacement to identify the location of bone marrow lesions.
- Trial name
- NCT00850538
- Testing
- MRI, Primary Total Knee Replacement
- Where
- Australia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Knee Arthroplasty, Knee Arthritis Osteoarthritis
Biomechanics of Gait Pattern Adaptation in Patients After Total Knee Arthroplasty
This study aimed to discover the biomechanics of gait pattern adaptation in patients after a total knee replacement. The first hypothesis of the project was that center-of-pressure manipulation at the foot during dynamic loading…
- Conditions
- Knee Arthroplasty, Knee Arthritis Osteoarthritis, Osteoarthritis, Osteoarthritis, Knee
- Trial name
- NCT01412814
- Testing
- AposTherapy Biomechanical System, Physical Therapy Program
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Total Elbow Replacement
Total Elbow Replacement in England: Analysis of National Joint Registry and Hospital Episode Statistics Data
The goal of this observational registry study is to provide detailed descriptions of the patients who are receiving primary total elbow replacement surgery in England.
- Trial name
- NCT06355011
- Testing
- Total Elbow Replacement
- Where
- United Kingdom
- Volunteers
- 3,891 people
- Sponsor
- University of Manchester
Knee Arthropathy, Hip Arthropathy
Analysis of Influencing Factors and Construction of Prediction Models of Artificial Joint Replacement in China
The project intends to analyze the epidemiological characteristics, risk factors, complications and resource utilization of artificial joint replacement in China through the inpatient data collected by the Hospital Quality…
- Conditions
- Knee Arthropathy, Hip Arthropathy, Shoulder Arthropathy, Ankle Arthropathy
- Trial name
- NCT05170321
- Where
- China
- Volunteers
- 600,000 people
- Sponsor
- Xiangya Hospital of Central South University
Osteoarthritis of Hip
Pedometer Based Intervention After Total Hip Replacement-A Pilot Study
Total hip replacement is designed to alleviate pain, reduce disability and improve function and physical activity levels. Whilst pain, disability and function are often measured following surgery, actual physical activity is not.
- Trial name
- NCT01972594
- Testing
- Targetted protocol with pedometer, Accelerometer(ActivPAL)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Ben Stansfield
Temporomandibular Joint Ankylosis, Facial Asymmetry
Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity
Hypothesis：Computer-aided design virtual mandibular position is feasible for costochondral graft growing and occlusion stabilizing in the one-stage treatment of children temporomandibular joint ankylosis (TMJA) or condyle absence…
- Trial name
- NCT03845088
- Testing
- temporomandibular jont reconstruction with costochondral transplantation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Peking University
Knee Osteoarthritis, Pain, Joint
Pain Function and QOL Undergoing Whole-Body Vibration and Exercise in End-Stage Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic progressive disease that imparts substantial socioeconomic burden to society and healthcare systems.
- Trial name
- NCT06183177
- Testing
- Whole-Body Vibration, Exercise
- Where
- Hong Kong
- Volunteers
- 517 people
- Sponsor
- Chinese University of Hong Kong
Hip Osteoarthritis
Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER)
Osteoarthritis (OA), leading to hip replacement, is a leading contributor to global mobility impairment. Given the boom in the older demographic it is not surprising that there is an 11% increased demand for replacement every 5…
- Trial name
- HIPPER (NCT02969512)
- Testing
- HIPPER, OASIS Online Educational Webinars
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of British Columbia
Osteoarthritis, Arthritis, Rheumatoid
Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee Prostheses
The purpose of the study is to evaluate the clinical performance of the cruciate ligament retaining or cruciate ligament substituting implants by obtaining a series of primary TKAs.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis
- Trial name
- NCT00289081
- Testing
- Total Knee Replacement
- Where
- 4 sites in United States
- Volunteers
- 399 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Degenerative Osteoarthritis, Rheumatoid Arthritis
VEGA Prospective Kiel
Voluntary Post-Marketing Clinical Follow-up (PMCF) as part of the post marketing surveillance plan for the product under investigation.
- Trial name
- NCT02802085
- Testing
- VEGA Knee
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Aesculap AG
Arthritis of the Knee
Unity Total Knee Replacement Using Two Different Surgical Techniques
This study will compare two different surgical methods used in total knee replacement with the Unity Total Knee Replacement System.
- Trial name
- NCT02145455
- Testing
- Unity Total Knee Replacement System
- Where
- United Kingdom
- Volunteers
- 111 people
- Sponsor
- Corin
Total Hip Replacement
Randomized Clinical Trial of Ceramic Bearing Primary Total Hip Arthroplasty
Primary total hip arthroplasty (THA) has been a very successful surgical intervention in the geriatric population. Numerous studies have reported good mid and long term results of THA in patients over the age of 60 years.
- Trial name
- NCT01522014
- Testing
- Secure-Fit™ arc-deposited Hydroxylapatite (HA) shell - surface ceramic and an Alumina Bearing Couple (ABC) ceramic insert and Ceramic C-taper head, Secure-Fit™ arc-deposited hydroxylapatite shell, a Crossfire® insert and a Ceramic C-taper head
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
Osteoarthritis, Hip, Arthritis
A Clinical Investigation of the M2a-Magnum™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a-Magnum™ Hip System
- Conditions
- Osteoarthritis, Hip, Arthritis, Rheumatoid Arthritis, Joint Disease
- Trial name
- NCT00698347
- Testing
- M2a-Magnum™ Hip System
- Volunteers
- 249 people
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthritis, Knee
Navio Robotic Versus Conventional Total Knee Arthroplasty
Total knee replacement surgery is a conventional approach to alleviating the pain and lack of function resulting from arthritis of the knee.
- Trial name
- NCT03519269
- Testing
- Navio™ Robotics-assisted Surgical System
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteoarthritis, Degenerative Joint Disease
Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial
The objectives of this research are to: Conduct a proof of concept randomized controlled trial with up to 300 patients undergoing primary total knee replacement (TKA) at Brigham and Women's Hospital (BWH).
- Trial name
- AViKA (NCT01540851)
- Testing
- Care Navigator, Standard Post-Operative TKA Care
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Brigham and Women's Hospital
Knee Pain Chronic, Rheumatoid Arthritis
Cemented vs Cementless Persona Keel RCT
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
- Conditions
- Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT05630053
- Testing
- Cementless Persona Knee System, Cemented Persona Knee System
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Postoperative Cognitive Decline, Biomarkers
Patients Experiences of Early Postoperative Cognition
The study has a mixed-methods design i.e. integration of qualitative and quantitative data within a single investigation. Participants included will be patients ≥60 years that are undergoing major elective joint replacement…
- Conditions
- Postoperative Cognitive Decline, Biomarkers, Postoperative Recovery, Joint Replacement Surgery
- Trial name
- COME (NCT05361460)
- Testing
- Cognitive decline
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Osteoarthritis, Knee
Does Rehabilitation After Total Knee Arthroplasty Work? - Feasibility Trial
The aim of this feasibility trial is to investigate the feasibility of a trial intervention for a population of patients after total knee replacement for osteoarthritis.
- Trial name
- DRAW-TKA-Fea (NCT05935020)
- Testing
- Usual care - Municipal exercise-based rehabilitation, Return to Everyday life, Symptom guide and encouragement to follow DHA/WHO recommendations for physical activity
- Where
- 2 sites in Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Hvidovre