Clinical trials: Joint Discomfort
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Knee Injuries, Cartilage Injury
Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee
Multi-center, prospective, concurrently controlled, non-randomized, double-blind (patient and assessor). Treatment of large chondral lesions in the knee with microfracture plus the Chondro-Gide® ACC is non-inferior to treatment…
- Conditions
- Knee Injuries, Cartilage Injury, Cartilage Disease, Knee Discomfort
- Trial name
- SECURE (NCT04537013)
- Testing
- Microfracture, Microfracture plus placement of Chondro-Gide® ACC
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 82 people
- Sponsor
- Geistlich Pharma AG
Knee Discomfort, Joint Pain
Turmeric Efficacy for Mobility and Joint Function
The objective of the study is to test the capacity of a 12-weeks Turmipure GOLD® supplementation to reduce joint discomfort.
- Trial name
- T-MOTION (NCT04506411)
- Testing
- Turmipure GOLD®, Turmeric rhizome PE 95% curcuminoids
- Where
- 8 sites in Croatia, Slovenia
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Low Intensity Knee Gonalgia
Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.
- Trial name
- NCT01303432
- Testing
- Yogurt supplemented with Mobilee, Yogurt
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Knee Discomfort, Pain Physical Activity
Polyherbal Capsule Formulation for Joint Health
This is a multicenter, randomized, double-blind, placebo-controlled, study in subjects with exercise-related knee pain/discomfort to determine the efficacy of a polyherbal capsule compared to placebo capsule in improving exercise…
- Trial name
- NCT02157701
- Testing
- Polyherbal capsule
- Where
- 5 sites in United States
- Volunteers
- 108 people
- Sponsor
- NewChapter, Inc.
Joint Pain
Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects
A Randomized, Double-Blind, Placebo-controlled, Parallel Design Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion \& Joint Discomfort in Healthy Subjects
- Trial name
- NCT05212259
- Testing
- Collagen type II (40 mg/day), Collagen type II (80mg/day), Collagen type II (120 mg/day)
- Where
- 10 sites in India
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Knee Discomfort, Knee Pain
Dietary Supplement for Joint: the OLE Study
This clinical study evaluates if the oral administration of Bonolive can contribute to the improvement of functionnality in healthy elderly people with knee discomfort.
- Trial name
- NCT03072108
- Testing
- Bonolive
- Where
- Belgium
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Pain
Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Joints and muscles disorders are common symptoms in the population. They are characterized by swelling, pain, functional impairment and morning stiffness.
- Trial name
- Easykrill (NCT02318875)
- Testing
- Kritech administration
- Where
- France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vivatech
Joint Discomfort
Efficacy and Safety of b-2Cool on Adults With Joint Discomfort
This study evaluates the effects of 40 mg of b-2Cool, a food supplement rich in native type-II collagen, on healthy adults with joint discomfort.
- Trial name
- NCT02843620
- Testing
- b-2Cool
- Sponsor
- Bioiberica
Hand Joint Discomfort
Evaluation of Flexofytol® PLUS in Hand Joint Chronic Dyscomfort.
The purpose of this study is to evaluate the effect of curcuminoids and Boswellia serrata extracts combination (Flexofytol PLUS) in support to standard treatments during a 12-weeks period on hand pain on people with chronic hand…
- Trial name
- NCT05089318
- Testing
- Flexofytol PLUS
- Where
- 2 sites in Belgium
- Volunteers
- 239 people
- Sponsor
- Tilman S.A.
Healthy Adult Male
Effect of Collavant® n2 in Healthy Male Adults With Exercise-induced Joint Discomfort.
The present clinical study has been designed to evaluate the effect of Collavant® n2 at a daily dose of 40 mg on joint function and performance in healthy, amateur male runners with exercise-induced knee discomfort.
- Trial name
- COLLMOTION (NCT07561203)
- Testing
- Native type II collagen (Collavant® n2)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Healthy Adult Male, Healthy Adult Females
Examining Olive Oil Extract on Knee Comfort and Function
The goal of this study is to learn if an olive oil extract works to improve knee pain and discomfort in adults. The main questions it aims to answer are: 1) Does the olive oil extract improve the perceptions of knee pain and…
- Conditions
- Healthy Adult Male, Healthy Adult Females, Joint Discomfort
- Trial name
- NCT07514013
- Testing
- Olive Oil Extract
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Applied Food Sciences Inc.
Joint; Derangement
Chondractiv Move on Activity-related Joint Discomfort
Joint discomfort, manifested as knee pain or gonalgia, is a common problem not only among athletes, but also among people who regularly take part in physical activities and sports.
- Trial name
- MOVIPLUS (NCT06714851)
- Testing
- Chondractiv Move
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Symrise Group
Joint Discomfort, Wellbeing
Assessing the Potential for Improved Joint Health and Wellbeing by Providing a Whole Salmon Oil With Undenatured Type II Collagen Compared to Type II Collagen Alone
This study evaluates the combination of NT-II® salmon undenatured type II collagen with OmeGo® salmon oil in adults who regularly experience knee discomfort.
- Conditions
- Joint Discomfort, Wellbeing, Quality of Life
- Trial name
- NCT07875101
- Testing
- Undenatured collagen, Whole salmon oil
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Hand Joint Discomfort, Hand Joint Dysfunction
Effect and Tolerance of Standardized Exclusive Dry Extracts of Curcuma Longa and of Boswellia Serrata Among People With Hand Joint Discomfort and Dysfunction
The objective of the study is to evaluate the effect and tolerance of standardized exclusive dry extracts of Curcuma longa (CURTIL03) and of Boswellia serrata (BOSTIL01) among people with hand joint discomfort and dysfunction.
- Trial name
- FLEXOA (NCT05570123)
- Testing
- Flexofytol Forte
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Tilman S.A.
Activity-Related Knee Discomfort, Joint Discomfort
NT-II™ Collagen for Joint Discomfort and Function
The goal of this clinical trial is to learn whether a natural marine supplement called NT-II™ (Salmon Undenatured Type II Collagen) can help lower knee discomfort caused by physical activity in otherwise healthy adults.
- Conditions
- Activity-Related Knee Discomfort, Joint Discomfort, Functional Joint Pain, Functional Knee Pain
- Trial name
- NTII-JOINT (NCT07119645)
- Testing
- NT-II™ (240 mg), NT-II™ 480 mg, Glucosamine/Chondroitin
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Hofseth Biocare ASA
Osteoarthritis, Knee
Evaluation of Mangoselect® in Improvement of Exercise/Activity-induced Knee Joint Discomfort in Subjects Suffering From Osteoarthritis Grade I or II
The aim of the present investigation is to evaluate the efficacy of Mangoselect®, a mangosteen extract, and of a formulation containing Mangoselect®, in subjects suffering from activity/exercise-induced knee joint…
- Trial name
- NCT04765189
- Testing
- Verum A, Verum B, Verum C
- Where
- Spain
- Volunteers
- 95 people
- Sponsor
- Fytexia
Joint Pain
Move Study in Healthy Aging People
Bone and muscle losses occur during ageing leading to increased risk of osteoporosis (there are more than 200 million people affected by osteoporosis worldwide), sarcopenia, loss of functionality and mobility.
- Trial name
- NCT02276183
- Testing
- Nutrition intervention, test formula, progressive physical activity
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Knee Discomfort
Effect of Consuming a Bioactive Compound (EPP) on Joint Health in Healthy Adults
The objective of this trial is to determine the efficacy of oral administration of a bioactive compound (EPP) in healthy individuals with mild knee joint discomfort.
- Trial name
- NCT06650670
- Testing
- Dietary Supplement: EPP
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Joint Pain
NAtive Collagen Type II In Healthy VoluntEers With Joint Discomfort
Collagen Supplement is a natural ingredient that contains native collagen derived from chicken sternum. Collagen Supplement is efficacious and safe on healthy subjects as compared to placebo.
- Trial name
- ACTIVE (NCT05282992)
- Testing
- Native type II collagen
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bioiberica