Clinical trials: Jaw Diseases
Nasal Septum; Deviation, Congenital, Cleft Lip and Palate
Three Dimensional Changes on Nasal Septum and Alveolar Cleft After Maxillary Expansion
This study evaluates, by means of cone beam computed tomography (CBCT), the alterations in the nasal septum and alveolar cleft volume that occur in cleft lip and palate (CLP) patients after rapid maxillary expansion(RME).
- Conditions
- Nasal Septum; Deviation, Congenital, Cleft Lip and Palate, Maxillary Hypoplasia
- Trial name
- NCT03976609
- Testing
- Maxillary Expansion
- Volunteers
- 40 people
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Cleft Lip, Scarring
Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair
Objective: To determine if the use of botulinum toxin during primary cleft lip repair improves the cosmetic appearance of the cleft lip scar
- Conditions
- Cleft Lip, Scarring, Cleft Palate
- Trial name
- NCT02247193
- Testing
- Botulinum Toxin Type A, Normal Saline Injection
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Temporomandibular Disorders (TMD), Pregnancy
Temporomandibular Joint Function, Oral Habits and Pain Complaints of Pregnant Women
The aim of this study is to examine the temporomandibular joint functions, oral habits and pain complaints of pregnant women. .
- Trial name
- NCT06760884
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Jaw, Edentulous, Jaw, Partially Edentulous
Prospective Registry of Immediate/Delayed Loading of Implants in the Cranial Bone-grafted Severely Atrophic Jaw
Edentulism is often associated with a negative psychosocial impact. The concept of prosthetic rehabilitation in which a prosthesis is supported by osseointegrated implants, was first introduced in the late 1960s by Brånemark et…
- Trial name
- ILICRAN (NCT02664298)
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Sint-Jan AV
Cleft Palate
Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth
This study aimed to evaluate clinically the "Alveolar extension" technique for palatoplasty in cases of primary closure of cleft palate regarding its effect on: 1. Eruption of Primary dentition. 2.
- Trial name
- NCT05286398
- Testing
- Palatoplasty, Addition silicone impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bisphosphonate-Associated Osteonecrosis of the Jaw, Osteonecrosis of the Jaw
Piezoeletric Surgery vs Conventional Surgery for Treatment of MRONJ
To date, surgical therapy of MRONJ remains the therapy of choice while still in association with a medical approach. Surgical intervention aims to stop the progression of the pathology through the removal of the tissue…
- Conditions
- Bisphosphonate-Associated Osteonecrosis of the Jaw, Osteonecrosis of the Jaw, Osteonecrosis Due to Drug
- Trial name
- PIEZOPZ-1 (NCT06622421)
- Testing
- Piezoelectric surgery, Conventional surgery
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT03962634
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Root Canal Therapy
Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations
A randomized, interventional, prospective, unicentric clinical study, 86 patients will be submitted to endodontic treatment of necrotic teeth.
- Trial name
- PBSCIMMO (NCT03514264)
- Testing
- Gutta Percha and AHPLUS cement (group A), PBS CIMMO cement (group B)
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Temporomandibular Joint Disorders, Voice Change
Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures
The present study aims to investigate the impact of temporomandibular joint dysfunction (TMD) on objective and subjective vocal parameters and the quality of life in affected patients.
- Trial name
- NCT06046521
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Temporomandibular Disorder
Assessment of Nociceptive Processing Among Patients With Temporo-mandibular Disorders
This case control study will investigate the physiological effect of nociceptive input in individuals with temporomandibular disorders.
- Trial name
- NCT04086732
- Testing
- High-frequency electrical stimulation
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate
Expiratory Muscle Strength Training for Hypernasal Speech in Children
When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency.
- Conditions
- Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence
- Trial name
- NCT05492266
- Testing
- Expiratory Muscle Strength Training, Maintenance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Noel Jabbour
Temporomandibular Joint Disorders
Occlusal Stabilization Splints Equilibrated by Different Techniques and Their Effect on TMD
The objective of the study is to evaluate if occlusal stabilization splints equilibrated by articulating paper will have equivalent effect in comparison to occlusal stabilization splints equilibrated by T-scan regarding the…
- Trial name
- NCT04661670
- Testing
- occlusal stabilization splints
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Fractures
Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) Plates
Mandibular fractures represent a significant portion of maxillofacial trauma, primarily resulting from motor vehicle accidents, interpersonal violence, and sports-related injuries.
- Trial name
- NCT07850570
- Testing
- Custom-Made Titanium Plate, Custom-Made PEEK Plate
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Pulp Disease, Dental, Pulp Necrosis
Chloramphenicol, Tetracycline, Zinc Oxide and Eugenol Paste (CTZ Paste) for Emergency Dental Treatment in Public Health Settings: A Randomized Trial
The treatment of pulpal diseases in primary teeth represents a significant challenge in public health, particularly in emergency dental care settings, where factors such as limited clinical time, low child cooperation, and…
- Conditions
- Pulp Disease, Dental, Pulp Necrosis, Pulp Therapy in Primary Molars, Primary Teeth
- Trial name
- CTZ- emergency (NCT07542639)
- Testing
- CTZ Paste, ZOE Pulpectomy
- Volunteers
- 110 people
- Sponsor
- University of Sao Paulo
Skin Carcinoma
Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back
RATIONALE: Drugs used in chemotherapy, such as tazarotene, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00783965
- Testing
- tazarotene
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Edentulous Jaw
Occlusion and Disocclusion Time in Immediately Loaded Overdentures Supported by Two Splinted Versus Non Splinted Interforaminal Implants
complete denture wearers struggle to eat well with their dentures due to poor denture retention, stability, and occlusal disharmony.
- Trial name
- NCT06376019
- Testing
- solitary Implant loading with ball attachment, splinted Implant loading with intra oral welding, complete denture
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Apical Periodontitis, Endodontic Disease
Postoperative Pain After OCT or EDTA Irrigation in Regenerative Endodontic Treatment
This randomized clinical trial evaluated the effect of two different irrigation solutions on postoperative pain following regenerative endodontic treatment of necrotic immature permanent teeth with apical periodontitis.
- Trial name
- NCT07722416
- Testing
- Regenerative Endodontic Treatment Using Different Irrigation Solutions
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Apical Periodontitis, Wound Heal
The Effect of MTA and PRF Application in Periapical Lesions
A total of 40 periapical lesions from the 33 patient undergoing apical surgery were randomly selected from December 2016-November 2017. Patients were informed about the surgical procedure and signed a consent form.
- Trial name
- NCT03743987
- Testing
- control group, MTA group, PRF group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Palate, Cleft
Evaluation of Quality of Life After Orthognathic Surgery in a Cleft Lip and Palate Context
The purpose of this study is to compare, prospectively, the quality of life of patients with cleft lip and palate before and after orthognathic surgery.
- Trial name
- ORTHOQOL (NCT04049058)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
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