Clinical trials: Jaw Atrophy
Alveolar Bone Loss
Subperiosteal Implants Constructed With Digital Technology
Atrophied jaw is a condition where there is insufficient bone quantity to place root form implants. Several treatment plans are available for treating atrophied jaws, including subperiosteal implants.
- Trial name
- NCT06012643
- Testing
- The purpose of this systematic review of case reports and case series was to evaluate the spectrum of subperiosteal implants for severely atrophied jaws using digital technology.
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss, Edentulous Jaw
Alloplastic Graft vs Xenograft for Horizontal Alveolar Ridge Augmentation
This prospective split-mouth randomized controlled trial compared horizontal alveolar ridge augmentation using alloplastic bone graft versus xenograft, both performed simultaneously with implant placement using the decompression…
- Trial name
- NCT07608744
- Testing
- Alloplastic bone graft, Xenograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ege University
Vertical Ridge Deficiency, Atrophic Maxilla
Fixation Free Sandwich Osteotomy With an Interpositional Inlay Graft in Compere to Conventional Sandwich Osteotomy
The atrophatic anterior maxilla present a considerable challenge for both surgical and prosthetic rehabilitation, as it may require bone augmentation to enable implant placement.
- Trial name
- sandwich (NCT06089928)
- Testing
- vertical augmentation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atrophic Maxilla, Ridge Preservation
Effect of L-PRF and A-PRF in Ridge Preservation
A split-mouth design study will be performed regarding the use of platelet concentrates on ridge preservation: L-PRF vs A-PRF vs control.
- Trial name
- NCT03268512
- Testing
- L-PRF, A-PRF
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ectodermal Dysplasia, Jaw, Edentulous
Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects
The amendment to Clinical Protocol 86-D-0015, clinical study of Oral Endosseous Titanium Implants in Edentulous subjects, and patients with Ectodermal Dysplasia is to allow the Investigators to determine: (1) If placement of…
- Trial name
- NCT00001211
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Alveolar Bone Loss
A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw
This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed.
- Trial name
- NCT02255149
- Testing
- Bone/Mesh
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Atrophic Maxilla, Zygomatic Implants
Computer Guided Placement of Zygomatic Implants in Two Different Approaches
Evaluation of computer guided placement of Zygomatic implants utilizing intra sinus versus extra sinus surgical approach for the reconstruction of atrophic maxilla.
- Trial name
- NCT06129695
- Testing
- Zygomatic implants
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandible Small
Augmentation of Atrophic Mandibule Using Poly Ether Ether Ketone Mesh
Comparative study between custom-made polyether ether ketone and titanium mesh for augmentation of atrophic posterior mandible.
- Trial name
- RCT (NCT04017117)
- Testing
- under local anasthesia,Ridge Augmention of posterior atrophic mandible by using mix of autogenous bone graft and bone substitutes is used under PEEK mesh
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bruxism, Muscular Disorders, Atrophic
Bruxism and Underlying Psichological Factors
The aim of this study was o determine the relationship between self-reported bruxism (SB) and some psychological factors (i.e: Anxiety State-Trait; Stress Reactivity Index, Beck Depression Inventory).
- Conditions
- Bruxism, Muscular Disorders, Atrophic, Temporomandibular Joint Disorders
- Trial name
- NCT06289608
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Edentulous Jaw
Adjunctive Benefit of Xenograft Plus a Membrane During Sinus Crestal Approach
Patients in need for implant-supported restoration in maxillary posterior sites with insufficient residual bone height will be randomly allocated to two different arms.
- Trial name
- NCT04662333
- Testing
- Transcrestal approach for sinus lift, Xenograft application
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Siena
Edentulous Jaw
Two Interforaminal Implants in an Immediate or Delayed Loading Protocol for the Elderly
The study population comprises 20 completely edentulous patients aged 60 years and older with severe mandible resorption. Each patient receives two inter-foraminal implants (Neoss Ltd., Harrogate, UK).
- Trial name
- NCT04292132
- Testing
- Implant placement, immediate loading, conventional loading
- Where
- Austria
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Alveolar Bone Atrophy
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting
A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard…
- Trial name
- Maxibone (NCT04297813)
- Testing
- Advanced medicinal Therapy (MSC combined with biomaterial), Autologous bone graft
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Atrophic Maxilla
Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
- Trial name
- NCT05400044
- Testing
- Three dimensional maxillary bone augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laser Therapy, Periodontal Diseases
Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth…
- Conditions
- Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss
- Trial name
- NCT07615361
- Testing
- Autogenous Tooth-Derived Bone Graft, Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Implant Site Reaction, Maxillary Deficiency
Radiographic Assessment of Bone Gain Following Sinus Lifting With Simultaneous Implant Placement Using Crestal Approach With Membrane Control Technique for Bone Augmentation of Atrophied Maxillary Posterior Ridge
This study aims to evaluate the quantity and quality of the native and the newly bone around dental implants that's simultaneously installed with sinus lifting
- Trial name
- NCT06446687
- Testing
- Dental implant with sinus lifting.
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osseodensification, Bone Expansion
Osseodensification for Narrow Alveolar Ridge Expansion
This prospective, single-arm, non-randomized interventional clinical study was designed to evaluate the immediate horizontal dimensional change in narrow alveolar ridges following osseodensification-assisted dental implant-site…
- Conditions
- Osseodensification, Bone Expansion, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- OD-RridgeExp (NCT07436533)
- Testing
- Densah burs (Osseodensification Technique)
- Where
- Yemen
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen