Clinical trials: Jaundice; Malignant
Biliary Obstruction
Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice
Background: When considering any malignancy with limited life expectancy, palliation and quality of life are paramount. Owing to the limited centres offering ERCP and endoscopic palliation in the South African state sector…
- Trial name
- NCT00731419
- Testing
- SEMS
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Cape Town
Jaundice Extrahepatic Obstructive, Disorder of Bile Duct Stent
Role of Endoscopic RFA in Prolonging the Patency of Metal Stents in Patients With Malignant Obstructive Jaundice
Patients with malignant obstructive jaundice (cancer of head of pancreas and cholangiocarcinoma) generally have a very poor prognosis with less than 20% patients having resectable disease at presentation.
- Trial name
- NCT01275768
- Testing
- Endoscopic radio-frequency ablation
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cholangitis Acute, Biliary Tract Diseases
Antimicrobial Resistance in Acute Cholangitis
This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to…
- Conditions
- Cholangitis Acute, Biliary Tract Diseases, Jaundice; Malignant, Jaundice, Obstructive
- Trial name
- ARISE (NCT06197984)
- Testing
- ERCP
- Where
- Romania
- Volunteers
- 1,435 people
- Sponsor
- Emergency County Hospital Pius Brinzeu; Timisoara, Romania
Jaundice
A Prospective, Randomized Study Evaluating the Effect of Biliary Stenting on EAU-FNA in Patients With Suspected Malignant Biliary Obstruction
Patients who present with obstructive jaundice due to a malignant stricture often undergo a battery of tests for diagnosis, treatment options, and prognosis.
- Trial name
- NCT01514058
- Testing
- EUS-FNA first, followed by CRCP with bilinary stenting, ERCP with stent placement, followed by EUS-FNA
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Complications
Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice
Patients with the lower malignant obstructive jaundice planned to do the pancreaticoduodenectomy, receiving preoperative biliary drainage or early surgery (without preoperative biliary drainage), both groups has the similar…
- Trial name
- NCT01744938
- Testing
- preoperative biliary drainage
- Volunteers
- 136 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Biliary Obstruction Due to Common Bile Duct Stone, Malignant Bile Duct Obstruction
Needle-Knife Fistulotomy Vs. Standard Cannulation Trial
Needle-knife fistulotomy (NKF) is traditionally used to achieve biliary access when standard cannulation (SC) techniques are unsuccessful.
- Trial name
- NCT06694038
- Testing
- Needle Knife Fistulotomy, standard biliary cannulation
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Thomas Jefferson University
Jaundice
Biliary Drainage in Patients With Duodenal Metal Stent
This is a retrospective study to evaluate the outcomes of endoscopic biliary drainage according to the timing of distal malignant biliary obstruction (MBO) in relation to gastric outlet obstruction (GOO) and the location of GOO.
- Trial name
- NCT02376907
- Testing
- Biliary drainage
- Where
- 25 sites in China, Hong Kong and 7 more
- Volunteers
- 200 people
- Sponsor
- Tokyo University
Pancreatic Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct
EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice
The main objective of the study is to evaluate the size of the common bile duct (CBD) in a large cohort of patients with jaundice secondary to pancreatic head or distal bile duct malignancy undergoing diagnostic EUS for tissue…
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct, Ampulla of Vater Cancer, Jaundice, Obstructive
- Trial name
- ECCO (NCT03494023)
- Testing
- Endoscopic ultrasound
- Where
- Romania
- Volunteers
- 539 people
- Sponsor
- Clinical Hospital Colentina
Distal Bile Duct Obstruction
Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction
The purpose of this study is to compare the rate of long-term stent failure, defined as need for repeat biliary intervention following placement of C-SEMS vs U-SEMS for palliation of inoperable malignant distal bile duct…
- Trial name
- NCT01905384
- Testing
- Covered Self-expanding metal biliary stents (C-SEMS), Uncovered Self-expanding metal biliary stents (U-SEMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center