Clinical trials: Ivermectin
Onchocerciasis
Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection
The primary purpose of this study was to determine the safety and tolerability of moxidectin in subjects infected with Onchocerca volvulus (a parasitic worm).
- Trial name
- NCT00300768
- Testing
- 2 mg moxidectin, ivermectin 150 mcg/kg, 4 mg moxidectin
- Where
- Ghana
- Volunteers
- 172 people
- Sponsor
- Medicines Development for Global Health
Covid19, Pneumonia
Comparative Therapeutic Efficacy and Safety of Different Antiviral and Anti Inflammatory Drugs in COVID-19 Patients.
Comparison outcomes of a large cohort of moderate and severe COVID-19 patients received different Antiviral and Anti Inflammatory Drugs.
- Trial name
- NCT04779047
- Testing
- Remdesivir, Hydroxychloroquine, Tocilizumab
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- October 6 University
Rosacea
MirvasO Soolantra Association In the Treatment of Moderate to Severe rosaCea.
The main objective of this study is to evaluate the efficacy of Ivermectin 1% cream (IVM) associated with Brimonidine 0.33% gel (Br) compared with the association of their respective vehicles in the treatment of moderate to…
- Trial name
- MOSAIC (NCT02616250)
- Testing
- Brimonidine 0.33% gel (Br), Ivermectin 1% cream (IVM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- Galderma R&D
Head Lice
A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects
The purpose of this study is to determine if 0.5% Ivermectin Cream is a safe and effective treatment for head lice infestations.
- Trial name
- LICE OUT (NCT01068158)
- Testing
- 0.5% Ivermectin Cream
- Where
- 7 sites in United States
- Volunteers
- 371 people
- Sponsor
- Topaz Pharmaceuticals Inc
Lice; Head Lice
A Bioequivalence Study, Comparing Two Formulations of Ivermectin Lotion, 0.5%
A Multi-Center, Double-Blind, Randomized, Placebo controlled, Parallel-group study, comparing Ivermectin Lotion, 0.5%
- Trial name
- NCT03257943
- Testing
- Ivermectin Lotion, 0.5%, SKLICE (ivermectin) Lotion, 0.5%, Vehicle of the Test product
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Bioequivalence
Bioequivalence of a Single-dose of 12 mg IVERMECTIN as Orally Disintegrating Mini Tablets Versus a Single-dose of 12 mg Regular IVERMECTIN Tablets in Healthy Adults Under Fasting Conditions
This is a phase I, single-center, open-label, randomized, two-period, two-way crossover, single-dose bioequivalence study in which the active substance ivermectin is administered as a single dose of 12 mg as either CHILD-IVITAB…
- Trial name
- CHILD-IVITAB (NCT05477810)
- Testing
- Treatment A (investigational drug) followed by Treatment B (reference drug), Treatment B (reference drug) followed by Treatment A (investigational drug)
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Covid19
Evaluation of Ivermectin Mucoadhesive Nanosuspension as Nasal Spray in Management of Early Covid-19
Ivermectin showed a strong viricidal effect upon covid19 virus in vitro as proved by many authors according to many studies , covid virus stay in postnasal space for 4 days before starting general manifestation, so ivermectin…
- Trial name
- NCT04716569
- Testing
- intranasal ivermectin spray
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- South Valley University
To Assess the Reduction in the Viral Load of SARS-CoV-2 in Patients Receiving Ivermectin Compared to Those Receiving Standard Care
Evaluation of the Impact of the Administration of Single Dose of Ivermectin in the Early Phase of COVID-19
The action of ivermectin in vitro on the viral replication of SARS-CoV-2 was demonstrated and published by an Australian team in June 2020.
- Trial name
- IVERCoV (NCT05040724)
- Testing
- Ivermectin
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Raincy Montfermeil Hospital Group
Covid19
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
Background: Up-to-date, there is no recognized effective treatment or vaccine for the treatment of coronavirus disease (COVID-19) that emphasize urgency around distinctive effective therapies.
- Trial name
- NCT04668469
- Testing
- Ivermectin, Hydroxychloroquine, personal protective Measures
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
COVID-19
Ivermectin for Severe COVID-19 Management
In this multicenter study; it was aimed to investigate the effectiveness and safety of ivermectin use in the treatment of patients with severe COVID-19 pneumonia that have no mutations which alter ivermectin metabolism and cause…
- Trial name
- NCT04646109
- Testing
- Ivermectin
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Strongyloides Stercoralis Infection
Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis
The study is an extension to the study StrongMoxi NCT04056325 and entails modifications based on the outcome of NCT04056325 part A. The study is a phase 3, double-blinded and randomized clinical trial conducted in Cambodia.
- Trial name
- StrongMoxi_KH (NCT04848688)
- Testing
- Moxidectin 2 mg, Ivermectin 3 mg
- Where
- Cambodia
- Volunteers
- 332 people
- Sponsor
- Jennifer Keiser
COVID-19 Pneumonia
Ivermectina Colombia (IVERCOL)
A parallel, prospective, double-blind, placebo-controlled clinical trial will be conducted in the population affiliated to EPS SURAMERICANA S.A. with positive test for antigen and PCR for SARS-CoV-2.
- Trial name
- IVERCOL (NCT04886362)
- Testing
- Ivermectin
- Volunteers
- 966 people
- Sponsor
- Ayudas Diagnosticas Sura S.A.S
Demodicidosis, Rosacea
Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis
The purpose of this study is to determine whether 0.5% ivermectin cream is effective in the treatment of demodicidosis (including papulopustular rosacea)
- Trial name
- NCT02036229
- Testing
- ivermectin cream 0.5%
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Pediculus Humanus Capitis (Head Lice)
Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation
This is a Phase 2 single center study designed to compare the safety, local tolerability, and efficacy of 3 strengths of ivermectin treatment conditioner to placebo.
- Trial name
- NCT00857948
- Testing
- ivermectin treatment conditioner
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Topaz Pharmaceuticals Inc
COVID
Max Ivermectin- COVID 19 Study Versus Standard of Care Treatment for COVID 19 Cases. A Pilot Study
At present, there are no specific treatments for COVID-19. WHO recommends four treatments for COVID 19 with drugs i.eRemdesivir, Lopinavir/ ritonavir, Lopinavir/ ritonavir with interferon beta -1a, and chloroquine or…
- Trial name
- NCT04373824
- Testing
- Ivermectin
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Max Healthcare Insititute Limited
Lymphatic Filariasis
Lymphatic Filariasis (LF) in Ivory Coast
The recommended treatment for elimination of LF in sub-Saharan Africa is annual mass drug administration (MDA) with single dose Albendazole (ALB) plus Ivermectin (IVM) given for at least 5-7 years.
- Trial name
- NCT02974049
- Testing
- Albendazole, Ivermectin, Diethylcarbamazine
- Where
- Côte d’Ivoire
- Volunteers
- 189 people
- Sponsor
- University Hospitals Cleveland Medical Center
Asymptomatic Infections, SARS-CoV2 Infection
Ivermectin vs Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 Infection
This is an open label randomised controlled study of oral ivermectin (600 mcg/kg/d* 3 day) versus combined of hydroxychloroquine plus darunavir/ ritonavir for 5 days treatment among asymptomatic carrier of SAR-CoV2 adult Thai…
- Trial name
- IDRA-COVID19 (NCT04435587)
- Testing
- Ivermectin Pill, Combined ART/hydroxychloroquine
- Where
- 4 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Covid19
Ivermectin In Treatment of COVID 19 Patients
as Egypt suffered a lot during the pandemic of COVID 19 with limited drug choices, many of the patients could not acheive viral clearence with the standard module of care teh idea of introduction of new medications in the…
- Trial name
- NCT04425707
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ministry of Health and Population, Egypt
Strongyloidiasis
Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis
Ivermectin is currently the best drug to cure strongyloidiasis, but the "standard" single dose of 200 mcg/kg is probably not enough to guarantee cure.
- Trial name
- STRONGTREAT (NCT01570504)
- Testing
- Ivermectin
- Where
- 9 sites in Italy, Spain and 1 more
- Volunteers
- 312 people
- Sponsor
- Centro per le Malattie Tropicali
COVID
Ivermectin as a Novel Therapy in COVID-19 Treatment
Efficacy of Ivermectin in COVID-19 treatment
- Trial name
- NCT04403555
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Tanta University