Clinical trials: Ischemic Stroke, completed
Stroke, Broca's Aphasia
Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.
The primary objective of this feasibility study is to evaluate the safety and effectiveness of targeted sub-threshold epidural cortical stimulation delivered concurrent with speech-language rehabilitation activities to enhance…
- Trial name
- NCT00170703
- Testing
- Cortical Electrical Stimulation
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Northstar Neuroscience
Stroke (CVA) or TIA, Fracture
Post-Stroke Osteopathy
The sudden biomechanical inactivation, direct neuro-humoral effects and sustained systemic stress reaction, which commonly occur after stroke or TIA, all may be of relevance in triggering alterations in bone metabolism and…
- Conditions
- Stroke (CVA) or TIA, Fracture, Fall
- Trial name
- NCT04845269
- Where
- Austria
- Volunteers
- 127 people
- Sponsor
- VASCage GmbH
Carotid Stenosis, Stroke
Structural Stability of Carotid Plaque and Symptomatology
The purpose of the research is to understand structural plaque abnormalities that make a carotid plaque unstable and brake off (embolize) which would help to predict and treat individuals who are likely to suffer not only classic…
- Conditions
- Carotid Stenosis, Stroke, Carotid Artery Plaque, Transient Ischemic Attack
- Trial name
- NCT02476396
- Testing
- Carotid Endarterectomy or Stenting
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- University of Wisconsin, Madison
Acute Ischemic Stroke, Acute Renal Injury
Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation
The aim of this trial is to assess the safety and efficacy of conestat alfa (Ruconest®, Pharming Technologies B.V.) on renal and cerebral ischemic events in patients undergoing TAVI for severe symptomatic aortic stenosis (AS)…
- Trial name
- PAIR-TAVI (NCT05145283)
- Testing
- Conestat alfa (Ruconest®), NaCl 0.9%)
- Where
- 2 sites in Switzerland
- Volunteers
- 141 people
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Stroke Hemorrhagic
Task-Specific Self-Rehabilitation Training (TASSRET) Trial
The goal of this pilot RCT is to evaluate the effectiveness of a Task-specific Self-rehabilitation Training (TASSRET) program and compare the effect of the two formats of the TASSRET (video vs manual) on functional ability (upper…
- Conditions
- Stroke, Stroke Hemorrhagic, Stroke Ischemic, Hemiparesis After Stroke
- Trial name
- TASSRET (NCT07208422)
- Testing
- Video-based Task-specific Training, Manual-based Task-specific Training
- Where
- Nigeria
- Volunteers
- 50 people
- Sponsor
- National Assembly Clinic
Ischemic Stroke
Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cells (IxCell hUC-MSC-S) in the Treatment of Ischemic Stroke
To evaluate the safety and tolerability of IxCellhUC-MSC-S as a single intravenous infusion in convalescent patients with ischemic stroke.
- Trial name
- NCT05697718
- Testing
- MSC
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- Shanghai IxCell Biotechnology Co., LTD
Hemiparesis, Ischemic Stroke
Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living
The investigators will study motor recovery after robot-assisted therapy after stroke. A small clinical trial will be conducted to quantify the central nervous system changes associated with robotic or standard training, and…
- Conditions
- Hemiparesis, Ischemic Stroke, Chronic
- Trial name
- NCT00878085
- Testing
- Robot Therapy Device, Occupational Therapy
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Phenprocoumon for the first…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947959
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Standard of care
- Where
- Germany
- Volunteers
- 665,533 people
- Sponsor
- Bayer
Ischemic Stroke
Radial Shock Waves for Functional Disability in Stroke
This is a double blind randomized clinical trial to evaluate the effect of radial shock waves on functional recovery of the upper limb of patients with sequelae of ischemic strokes in the territory of the middle cerebral artery.
- Trial name
- NCT02924168
- Testing
- Active Radial Shockwave
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Marta Imamura
Acute Ischemic Stroke, Hypothermia
Safety and Efficacy of Selective Intra-Arterial Cooling Infusion Combined With EVT in Acute Ischemic Stroke
This is a multicenter, randomized, controlled, subject- and assessor-blinded clinical trial. The research objective is to evaluate the safety and efficacy of selective intra-arterial cooling infusion combined with endovascular…
- Trial name
- FOCUS (NCT06485427)
- Testing
- Selective Intra-arterial Cooling Infusion (IA-SCI)
- Where
- 12 sites in China
- Volunteers
- 258 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Embolic Stroke of Undetermined Source
Young ESUS Patient Registry
This study seeks to determine the clinical characteristics of young ESUS patients using diagnostic criteria of the Cryptogenic Stroke / ESUS International Working Group, and to determine the rates of stroke recurrence, death, and…
- Trial name
- Y-ESUS (NCT03185520)
- Where
- 44 sites in United States, Argentina and 11 more
- Volunteers
- 535 people
- Sponsor
- Population Health Research Institute
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Stroke, Acute, Infarction, Middle Cerebral Artery
Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment.
The aim of the study is to determine the safety and efficacy on an autologous CD34+ subset bone marrow stem cell infusion into the middle cerebral artery in patients who have suffered acute middle cerebral artery stroke.
- Trial name
- NCT00761982
- Testing
- Infusion on autologous CD34+ stem cells into middle cerebral artery
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario Central de Asturias
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ischemic Stroke
Effect of Different Feeding Modes on Psychological Condition and Experience in Stroke Patients
The goal of this clinical trial is to compare the differences on Psychological Condition and Experience in ischemic stroke patients using Intermittent Oro-esophageal Tube and Nasogastric Tube.
- Trial name
- NCT06328894
- Testing
- Nasogastric Tube Feeding, Intermittent Oro-esophageal Tube Feeding, comprehensive rehabilitation therapy
- Where
- 2 sites in China
- Volunteers
- 156 people
- Sponsor
- Zeng Xi
Ischemic Stroke
A Study of Survival and Outcome After Stroke
The objective of this study is to determine the natural history of acute ischemic stroke from large vessel thromboembolism in the brain.
- Trial name
- SOS (NCT01193569)
- Where
- United Kingdom
- Volunteers
- 142 people
- Sponsor
- Penumbra Inc.
Traumatic Brain Injury, Subarachnoid Hemorrhage
NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
This is an observational study in neurocritical care units at University of California San Francisco Medical Center (UCSFMC), Zuckerberg San Francisco General Hospital (ZSFGH), UC Davis, and Emory University.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure
- Trial name
- NOVEL ICP (NCT04548596)
- Testing
- Transcranial Doppler
- Where
- 3 sites in United States
- Volunteers
- 162 people
- Sponsor
- Emory University
Neuro-intensive Care Unit Patients, Subarachnoid Hemorrhage, Aneurysmal
Risk Factors and Outcomes in Patients Treated in Neurocritical Care
The overall purpose of this epidemiologic research project is to provide a comprehensive exploration and analysis of critical elements within the neuro-intensive care process in Sweden.
- Conditions
- Neuro-intensive Care Unit Patients, Subarachnoid Hemorrhage, Aneurysmal, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- EpiNIC (NCT07052656)
- Testing
- Observational study, participants are not assigned an intervention as part of the study., Transport modality
- Where
- Sweden
- Volunteers
- 70,000 people
- Sponsor
- Karolinska Institutet
Stroke, Cardiovascular
Effect of Motor Imaginary Training on Upper Limb Functions in Stroke
This study will provide knowledge about effectiveness of motor imaginary training in upper limb performance in chronic stroke patients.
- Trial name
- NCT05008822
- Testing
- Motor Imaginary Training Group, Task oriented Training Group
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Minor Stroke
Thrombolysis of Urokinase for Minor Stroke
This trial will enroll patients that have been diagnosed with minor stroke, which has occurred within the past 6 hours. TRUST is a prospective multicenter, randomized, blinded-endpoint study to evaluate the efficacy and safety of…
- Trial name
- TRUST (NCT04420351)
- Testing
- Urokinase thrombolysis, Aspirin;Clopidogrel
- Where
- China
- Volunteers
- 1,005 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
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