Clinical trials: Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome, Constipation
Nutrition to Relieve IBS Constipation
Rationale: Irritable Bowel Syndrome (IBS) is a disease that affects a large number of people. To date, no adequate treatment is available.
- Trial name
- NUTRIC (NCT04798417)
- Testing
- Probiotic supplement, Prebiotic supplement, Maltodextrin
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Wageningen University and Research
Irritable Bowel Syndrome With Diarrhea
12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)
Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea.
- Trial name
- IRIS-05 (NCT02320318)
- Testing
- Ibodutant 10 mg
- Where
- 20 sites in Singapore, South Korea and 1 more
- Sponsor
- Menarini Group
Irritable Bowel Syndrome With Constipation (IBS-C)
A Study of the Effect of SYN-010 on Subjects With IBS-C
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared with Placebo on Breath Methane Production in Breath Methane-Positive Subjects with…
- Trial name
- NCT02495623
- Testing
- SYN-010 21 mg, SYN-010 42 mg
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Theriva Biologics, Inc.
Irritable Bowel Syndrome With Constipation (IBS-C)
Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients
The purpose of this study is to understand how a drug called Linaclotide improves bowel function and abdominal pain in patients with Irritable Bowel Syndrome with Constipation (IBS-C) as well as to examine whether Linaclotide…
- Trial name
- NCT02078323
- Testing
- Linaclotide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Augusta University
Irritable Bowel Syndrome
Effects of Vivatlac Synbiotic on Gut Micribiota of IBS Patients
Multi-center, randomized, double-blind, placebo-controlled, 12 weeks trial investigating the effects of a nine-strain synbiotic (Vivatlac Synbiotikum) on the gut microbiota of IBS patients
- Trial name
- ViIBS3 (NCT07235228)
- Testing
- Vivatlac Synbiotic
- Where
- 2 sites in Poland
- Volunteers
- 20 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
IBS - Irritable Bowel Syndrome
Treatment Efficacy of Low FODMAP Versus Low Lactose Diet in IBS Patients
A low FODMAP diet (LFD) has become a standard treatment in irritable bowel syndrome (IBS) patients. Compliant adherence to a LFD is challenging.
- Trial name
- NCT04543474
- Testing
- Low Lactose Diet, Low FODMAP Diet
- Volunteers
- 30 people
- Sponsor
- Cantonal Hospital of St. Gallen
Irritable Bowel Syndrome
Comparing the Effectiveness of 2 Diets for Patients With Irritable Bowel Syndrome
The purpose of the study is to find out if the diets often recommended for patients with Irritable Bowel Syndrome with diarrhea (IBS-D) provide adequate relief.
- Trial name
- NCT01624610
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance
Previous studies have shown that stool transplantation (FMT) have positive effect in symptoms for some patients with irritable bowel syndrome (IBS).
- Trial name
- FinFMT-IBS (NCT05361785)
- Testing
- FMT
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Helsinki University Central Hospital
Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome Survey in Gastroenterological Adult Outpatients in China
The primary objective of this study is to estimate the overall prevalence of IBS medically diagnosed and diagnosed using Rome III or IV criteria in GI adult outpatients in China.
- Trial name
- IRONS (NCT02955316)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Irritable Bowel Syndrome
Treatment of Irritable Bowel Syndrome (IBS) With Sacral Nerve Stimulation
Sacral nerve stimulation (SNS) has become a well-established treatment for patients with fecal incontinence since 1995. The mechanism of action of SNS is still not fully understood but recent studies have shown that the motility…
- Trial name
- NCT00919672
- Testing
- Sacral nerve stimulation
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Irritable Bowel Syndrome With Diarrhea
Clinical Study to Evaluate the IBS Symptoms Improving Effect and Safety of GTB1
This study was conducted to investigate the effects of daily supplementation of L. plantarum APsulloc 331261(GTB1TM) on improvement of IBS symptoms.
- Trial name
- NCT05277428
- Testing
- GTB1
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Irritable Bowel Syndrome (IBS), Anxiety
Anxiety and Depression in IBS: A Brain-Gut Axis Study
This study aims to understand how the gut and the brain communicate in people with Irritable Bowel Syndrome (IBS) who also experience anxiety and depression.
- Conditions
- Irritable Bowel Syndrome (IBS), Anxiety, Depression
- Trial name
- NCT07646834
- Testing
- Observational Study (No Intervention)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Irritable Bowel Syndrome
Saccharomyces Cerevisiae for Irritable Bowel Syndrome
This study is designed to see the response of saccharomyces cerevisiae for symptomatic improvement of patients with IBS
- Trial name
- IBS (NCT05149599)
- Testing
- Saccharomyces cerevisiae
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ziauddin University
Irritable Bowel Syndrome-bile Acid Diarrhea
A Study of Hemp Hull WFI for IBS Diarrhea
The purpose of this study is the effect of a study bar, which contains 15 grams of insoluble dietary fiber total sourced from Hemp hulls, on intestinal permeability in irritable bowel syndrome (IBS)-bile acid diarrhea individuals.
- Trial name
- NCT06028035
- Testing
- BB01
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome
A Study Comparing the Effectiveness and Convenience of Dietary Therapy for Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome is a functional lower gastrointestinal disorder characterised by abdominal pain and altered bowel habit in the absence of organic pathology to explain the symptoms.
- Trial name
- NCT04072991
- Testing
- dietary therapy
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Irritable Bowel Syndrome
Is Microbiota Community Associated With Clinical Response to a Low FODMAP Diet in Patients With Irritable Bowel Syndrome
To determine the efficacy of a low FODMAP diet in IBS patients and whether gut microbiota community is associated with its efficacy.
- Trial name
- NCT02565550
- Testing
- low FODMAPs
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shandong University
Irritable Bowel Syndrome (IBS), Vitamin D Deficiency
Role of Vitamin D Supplementation in Children With Irritable Bowel Syndrome
This study was designed to determine whether vitamin D supplementation improved symptoms in children with irritable bowel syndrome, a condition associated with repeated abdominal pain and changes in bowel habits.
- Trial name
- NCT07914478
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aziz Bhatti Shaheed Teaching Hospital
Inflammatory Bowel Disease, Irritable Bowel Syndrome
BÜHLMANN fCAL™ ELISA - Aid in Differentiation of IBD From IBS
The purpose of this study is to confirm the sensitivity and specificity of the BÜHLMANN fCAL™ ELISA as an aid in diagnosis to differentiate between Inflammatory Bowel Disease (IBD; Crohn's Disease (CD), Ulcerative Colitis (UC)…
- Trial name
- NCT02351635
- Testing
- fecal calprotectin level
- Where
- 7 sites in United States
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Bühlmann Laboratories AG
Diarrhea- Irritable Bowel Syndrome
The Effect of Neu-P11 on Symptoms in Patients With D-IBS
Placebo controlled double-blind study with 40 patients who have an diarrhea-predominant IBS, 20 get Neu-P11, 20 get a placebo. Neu-P11 is a, Melatonin receptor-, Serotonin 5-HT- 1A and 5-HT- 1D - agonist and a serotonin 5-HT- 2B…
- Trial name
- Neu-P11 (NCT01558284)
- Testing
- Neu-P11
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ludwig-Maximilians - University of Munich