Clinical trials: Irritable Bowel Disease
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care
The goal of this randomised controlled trial is to study the (cost-)effectiveness of home-based hypnotherapy by self-exercises in children with functional abdominal pain (FAP) or irritable bowel syndrome (IBS) in primary care.
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
- Trial name
- ZelfHy (NCT05636358)
- Testing
- Home-based hypnotherapy
- Where
- Netherlands
- Volunteers
- 152 people
- Sponsor
- University Medical Center Groningen
Abdominal Pain, Inflammatory Bowel Diseases
Understanding Abdominal Pain in IBD and IBS
Abdominal pain is a central symptom of Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). IBD is an autoimmune disease characterized by inflammation of the gastrointestinal tract.
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Irritable Bowel Syndrome
- Trial name
- NCT04020835
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Irritable Bowel Syndrome
Trans-cutaneous Vagal Nerve Electrical Stimulation and Irritable Bowel Syndrome
This pilot study plan to investigate the sympathovagal balance in women affected by Irritable Bowel Syndrome (IBS), and to evaluate the effect of 6 months of trans-cutaneous vagal nerve electrical stimulation on digestive…
- Trial name
- StVSII (NCT02420158)
- Testing
- Trans-cutaneous vagal nerve electrical stimulation
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Constipation, Irritable Bowel Syndrome
Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation
Chronic constipation (CC) and Irritable Bowel Syndrome with Constipation (IBS-C) are two conditions difficult to manage because factors affecting dissatisfaction to treatments are misleading.
- Trial name
- NCT02813616
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
IBS - Irritable Bowel Syndrome
Ashtangayoga for IBS Show Positive Preliminary Effects on Symptoms and Well-being
The study aims to test the effect of Ashtanga yoga on well-being in patients with irritable bowel syndrome (IBS). The intervention comprises group sessions on the Ashtanga school of yoga.
- Trial name
- NCT04946604
- Testing
- Ashtangayoga
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome
Curcumin (Tumeric) in the Treatment of Irritable Bowel Syndrome: A Randomized-Controlled Trial
Evidence exists to support low-grade inflammation as the inciting factor leading to visceral hypersensitivity and alteration in motility in irritable bowel syndrome.In the medical literature,there is ample in vitro and in vivo…
- Trial name
- CuTIBS (NCT00779493)
- Testing
- curcumin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Irritable Bowel Syndrome, Constipation
Cognitive Behaviour Therapy for Patients With IBS
Irritable bowel syndrome (IBS) affects approximately 10-15% of the adult population. This condition is characterized by abdominal pain, altered bowel habit, abdominal bloating and reduced quality of life.
- Conditions
- Irritable Bowel Syndrome, Constipation, Abdominal Pain, Depression
- Trial name
- EFI (NCT00788658)
- Testing
- Diet modifications, Cognitive behavioral therapy
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Irritable Bowel Syndrome
Efficacy of Hydrogen Breath Test in the Patients With Irritable Bowel Syndrome
Irritable bowel syndrome is characterized by abdominal discomfort and bowel habit change. It is increasing worldwide. But the pathophysiology of the irritable bowel syndrome is not proven.
- Trial name
- NCT02242175
- Testing
- Glucose breath test (hydrogen breath test)
- Where
- South Korea
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Irritable Bowel Syndrome, Disorders of Gut-brain Interaction
Audio-recorded Gut-Hypnotherapy for Sleep and Pain in Pediatric Abdominal Pain Disorders
Children with irritable bowel syndrome (IBS) and functional abdominal pain- not otherwise specified (FAP-NOS) have higher rates of poor sleep quality.
- Trial name
- NCT07216092
- Testing
- Gut-directed Hypnotherapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Children's Hospital at Montefiore
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe
Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders
The aim of this multi-center, two-armed, randomized controlled trial is to assess the effect of a novel internet-based therapist-assisted treatment program "One step at a time" designed for the treatment of patients with moderate…
- Conditions
- Bodily Distress Disorder Moderate, Bodily Distress Disorder Severe, Fibromyalgia, Chronic Fatigue Syndrome
- Trial name
- OneSTEP (NCT05525598)
- Testing
- "One step at a time", "Get started"
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- University of Aarhus
Irritable Bowel Syndrome, Constipation
Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation
Irritable bowel syndrome (IBS) is a common disorder which presents with abdominal pain or discomfort in association with altered bowel habit.
- Trial name
- NCT01162863
- Testing
- Lubiprostone, Smartpill wireless motility capsule
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome, Microbial Colonization
Microbiota Profiling in IBS
This study investigates differences in microbiota profiles and metabolite levels between mild and severe IBS patients, compared to matched healthy controls. Two fecal samples, with one month in between, will be analyzed.
- Conditions
- Irritable Bowel Syndrome, Microbial Colonization, Dietary Habits
- Trial name
- IBSQUtrition (NCT03720314)
- Testing
- NA observational study
- Where
- Netherlands
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Wageningen University
IBS - Irritable Bowel Syndrome, Inflammation
Study of Inflammatory Markers and Symptom Severity in Personalized Nutritional Intervention in IBS
Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life.
- Trial name
- NCT04348760
- Testing
- Rotation Diet
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- GEK Srl
Irritable Bowel Syndrome
Probiotics in Intestinal Bacterial Overgrowth
The aim of the present study is to demonstrate the effect of a mixture of four species of probiotics (Saccharomyces boulardii, Bifidobacterium lactis BB-12, Lactobacillus acidophilus LA-5 and Lactobacillus plantarum) in patients…
- Trial name
- NCT02204891
- Testing
- Probiotics in SIBO, Probiotics
- Where
- Greece
- Volunteers
- 26 people
- Sponsor
- University of Athens
Irritable Bowel Syndrome
Effect of Electroacupuncture in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is the most common digestive disorder that affects more than 5% of population in Hong Kong. However, there is no effective treatment of IBS using Western Medicine.
- Trial name
- IBS_FBM (NCT00900965)
- Testing
- Electroacupuncture treatment (electrical stimulation machine (EY-3308 Model, G6805-2 Mayfair))
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Chinese University of Hong Kong
IBS - Irritable Bowel Syndrome, Microbial Substitution
The Optimal Route of Fecal Microbiota Transplantation for Irritable Bowel Syndrome
The object of this study is to find out is there an optimal route for the fecal microbiata transplant (FMT) in patients that suffer from irritable bowel syndrome.
- Trial name
- NCT05874830
- Testing
- Fecal microbiota transplant or plasebo through endoscopy
- Where
- 3 sites in Finland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Irritable Bowel Syndrome, Constipation
Treatment of Functional Bowel Disorders
The primary purpose for this study is to compare clinical treatments for patients with functional bowel disorders (irritable bowel syndrome, abdominal pain, painful constipation) in women.
- Conditions
- Irritable Bowel Syndrome, Constipation, Abdominal Pain, Functional Colonic Diseases
- Trial name
- NCT00006157
- Testing
- Desipramine, Cognitive Behavioral Treatment
- Where
- 2 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C)
"Efficacy and Safety of Linaclotide in Chronic Constipation"
Goal of this study is to evaluate the efficacy and safety of two different doses of Linaclotide in improving bowel function and patient-reported outcomes among Bangladeshi patients with chronic constipation for 8 weeks along with…
- Conditions
- Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C), Chronic Constipation, CIC
- Trial name
- LIN-CC-BD (NCT07431957)
- Testing
- Linaclotide 72 micrograms, Linaclotide 145 micrograms
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Md Mehedi Shahriar
Patients With Irritable Bowel Syndrome With Diarrhea
Huanghou Zhixie Diwan in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D)
This trial is a randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase II clinical trial. Its purpose is to evaluate the efficacy and safety of Huanghou Zhixie Diwan in subjects with irritable bowel…
- Trial name
- NCT07721012
- Testing
- Huanghou Zhixie Diwan group, Huanghou Zhixie Diwan mimic
- Where
- 14 sites in China
- Volunteers
- 120 people
- Sponsor
- Lei Yunshang Group
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