Clinical trials: Irreversible Pulpitis
Postoperative Dental Pain, Root Canal Sealers
Effect of Different Root Canal Sealers on Postoperative Pain
This randomized clinical trial aimed to evaluate postoperative pain following the use of bioceramic and epoxy resin-based root canal sealers in combination with the continuous wave of condensation technique (CWCT), addressing a…
- Conditions
- Postoperative Dental Pain, Root Canal Sealers, Asymptomatic Irreversible Pulpitis
- Trial name
- NCT06726837
- Testing
- Postoperative pain - 6th hour, Postoperative pain - 24th hour, Postoperative pain - 48th hour
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dicle University
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible, Apical Periodontitis
Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed…
- Trial name
- NCT05902936
- Testing
- Pulpotomy for mature permanent mandibular molars
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP)
COMT, MAOA, and SLC6A4 Polymorphisms and Inferior Alveolar Nerve Block Success
The purpose of this study was to evaluate the association between COMT, MAOA, and SLC6A4 genetic polymorphisms and the success of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT07697300
- Testing
- Inferior Alveolar Nerve Block with 4% Articaine
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pulpitis - Irreversible
Prognostic Biomarkers for Pulpotomy Outcome
This study will recruit 180 molars diagnosed with irreversible pulpitis. Full pulpotomy will be performed on 120 teeth, while RCT (root canal treatment) will be conducted on another cohort of 60 teeth as the control for assessing…
- Trial name
- NCT06514053
- Testing
- Full pulpotomy, Root canal treatment
- Where
- Hong Kong
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cryotherapy Effect, Irreversible Pulpitis
Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children
The aim of the study is to assess the efficacy of cryotherapy application on the success of inferior alveolar nerve block (IANB) in reducing pain during pulp therapy of the mandibular first permanent molars with irreversible…
- Conditions
- Cryotherapy Effect, Irreversible Pulpitis, Pain
- Trial name
- NCT05441995
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Minia University
Anesthesia; Reaction, Pain
Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques
The purpose of this study is to determine whether Gow Gates block injection is more effective than conventional alveolar nerve block in anesthetising mandibular molars with acute pulpitis.
- Trial name
- NCT01329874
- Testing
- Type of block injection
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Irreversible Pulpitis
Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars
The primary aim is to compare the behavior of the children during using conventional manual instrumentation versus rotary instrumentation by single rotary system for pulpectomy in primary molars through a Randomized Clinical…
- Trial name
- NCT07415694
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Pulpotomy vs.Root Canal Treatment in Managing Irreversible Pulpitis
The study aims to compare two methods of repairing and saving a badly damaged or infected tooth. One method is called root canal treatment (RoCT) and the other (new method) is called pulpotomy.
- Trial name
- NCT03956199
- Testing
- pulpotomy, Root canal treatment
- Where
- 3 sites in United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- King's College London
Pulpitis - Irreversible
The Effect of Prognostic Factors on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible Pulpitis
This study aims to evaluate the effect of prognostic factors, such as the degree of pulpal inflammation and the radiographic caries depth, on the success of full pulpotomy in mature permanent molars with irreversible pulpitis.
- Trial name
- NCT06597487
- Testing
- Full pulpotomy, Conventional root canal treatment
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Misr International University
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Irreversible Pulpitis, Failed Inferior Alveolar Nerve Block
Articaine Versus Lidocaine for Supplemental Buccal Infiltration in Lower First Molars With Irreversible Pulpitis
Local anesthetic is used to numb a tooth before a root canal treatment. In lower back teeth with irreversible pulpitis (a painful, inflamed tooth nerve), the standard numbing injection near the jaw nerve, called an inferior…
- Trial name
- ARTLID-IP (NCT07869394)
- Testing
- Articaine 4% with epinephrine 1:100,000, Lidocaine 2% with Epinephrine 1:100,000
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rehman Medical Institute - RMI
Pulpitis - Irreversible
Single Rotary File Pulpectomy in Primary Molars
The aim of this study is to compare the clinical effectiveness of a single rotary file system versus a multiple rotary files system in pulpectomy of primary molars
- Trial name
- NCT06146686
- Testing
- Fanta AF blue rotary files 20 taper 4, Fanta AF baby rotary files 20 , 25 , 30 taper 4
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Effect of Cryotherapy on Postoperative Pain
the aim of the study is to evaluate the effect of cryotherapy on postoperative pain in molar teeth with irreversible pulpitis and apical periodontitis
- Trial name
- NCT03716635
- Testing
- cryotherapy, normal saline
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: A RCT
Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis.
- Trial name
- NCT05681494
- Testing
- Root canal treatment, Vital pulp therapy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Irreversible Pulpitis
Evaluation of Bacterial Reduction After Pulpectomy in Primary Molars
The primary aim of the study is to compare the bacterial reduction in pulpectomy of primary molars using a single rotary file system versus conventional manual instrumentation.
- Trial name
- NCT07472751
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Irreversible Pulpitis
Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis
To compare the effect of different VPT methods using Calcium Enriched Mixture (CEM) cement for management of human dental pulp with irreversible pulpitis.
- Trial name
- NCT01561183
- Testing
- Indirect pulp capping (IPC), Direct pulp capping (DPC), Miniature pulpotomy (MP)
- Where
- Iran
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Pain, Symptomatic Irreversible Pulpitis
The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste
In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.
- Trial name
- NCT05600023
- Testing
- Nitrofurantoin, Double Antibiotic
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine