Clinical trials: Irreversible Pulpitis
Irreversible Pulpitis
Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars
The primary aim is to compare the behavior of the children during using conventional manual instrumentation versus rotary instrumentation by single rotary system for pulpectomy in primary molars through a Randomized Clinical…
- Trial name
- NCT07415694
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Molar Incisor Hypomineralisation, Irreversible Pulpitis
Pain Assessment Governing Partial or Full Pulpotomy of Immature Molars With Irreversible Pulpitis in Molar Incisor Hypomineralization
This randomized controlled clinical trial aims to evaluate and compare pain levels associated with partial pulpotomy (PP) and full pulpotomy (FP) in immature permanent first molars diagnosed with irreversible pulpitis.
- Conditions
- Molar Incisor Hypomineralisation, Irreversible Pulpitis, Immature Molars
- Trial name
- NCT07850986
- Testing
- pulpotomy for MIH affected immature PFMs, partial pulpotomy for MIH affected immature PFMs, pulpotomy for non-MIH affected immature PFMs
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alaa Khafagy
Irreversible Pulpitis, Diabetes Mellitus, Type 2
Outcome of Complete Pulpotomy in Healthy and Type 2 Diabetic Patients in Permanent Teeth With Irreversible Pulpitis
Endodontic research on the effects of DM on pulp tissues is scarce. Diabetic human and animal histological research demonstrated a decreased reparatory response in the pulp, resulting in chronic pulp inflammation and reduced…
- Conditions
- Irreversible Pulpitis, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT06586775
- Testing
- Pulpotomy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Irreversible Pulpitis
The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain
The goal of this clinical trial is to compare the effect of cooling of local anesthesia on intraoperative pain during root canal treatment in mandibular molars diagnosed as symptomatic irreversible pulpitis.
- Trial name
- NCT06194721
- Testing
- Cold intrapulpal anesthesia, Room temperature intrapulpal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Irreversible Pulpitis
The Effect of Totalfil and Neosealer Sealers on the Post-endodontic Pain
The goal of this clinical trial is to evaluate the effect of Totalfil and Neosealer sealers on post-endodontic pain compared to AH plus sealer in mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT06194773
- Testing
- Totalfil, NeoSealer, AH-Plus sealer
- Where
- United Arab Emirates
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Irreversible Pulpitis With Apical Periodontitis
The Effect of Eddy Sonic Versus AF Max Activation of Bio-ceramic Sealer on Post-operative Pain in Teeth With Symptomatic Irreversible Pulpitis With Apical Periodontitis
The aim of endodontic therapy for an inflamed tooth is to eliminate the source of inflammation. Relieving pain depends on the effectiveness of root canal therapy.3 Postoperative pain in endodontic treatments, affecting 3-58% of…
- Trial name
- NCT06640218
- Testing
- sealer activation with Eddy sonic and AF max, without AF max or Eddy sonic sealer activation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis (SIP)
Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment
This randomized control trial will be planned according to PRIRATE 2020 guideline for reporting randomized trials in Endodontics.
- Trial name
- NCT07759349
- Testing
- Acetaminophen, NSAID, trypsin-chymotrypsin
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Irreversible Pulpitis With Apical Periodontitis
Full Pulpotomy in Permanent Teeth With Irreversible Pulpitis and Apical Periodontitis
This study will evaluate whether full pulpotomy can successfully treat mature permanent teeth with irreversible pulp inflammation and a periapical lesion.
- Trial name
- NCT07768852
- Testing
- Full pulpotomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Irreversible Pulpitis
Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis
This is a clinical trial to assess the treatment outcomes of pulpotomy in vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06149845
- Testing
- Full Pulpotomy
- Where
- 2 sites in Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06183203
- Testing
- Pulpotomy, Pulpectomy
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nebu Philip
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy Versus Pulpectomy in Vital Primary Molars Diagnosed With Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06904781
- Testing
- Pulpotomy, Pulpectomy
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Qatar University
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Reversible Pulpitis, Irreversible Pulpitis
Biomarkers for Differentiating Reversible and Irreversible Pulpitis
This observational study aims to evaluate the role of inflammatory, oxidative stress, neurogenic, and immunological biomarkers obtained from pulpal blood in the differential diagnosis of normal pulp, reversible pulpitis, and…
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Healthy Pulp
- Trial name
- PULPBIOM (NCT07658742)
- Testing
- Pulpal Blood Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Safa
Symptomatic Irreversible Pulpitis
The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain
Pain is a very important factor in Endodontic treatment, Both intra- and Post-operatively. In case of symptomatic Irreversible pulpitis, a build up of inflammatory mediators makes it very difficult for the operator to reach the…
- Trial name
- NCT06298383
- Testing
- Trypsin, Bromelain and Rutoside, Diclofenac Potassium 50mg Tab, Prednisolone Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP)
COMT, MAOA, and SLC6A4 Polymorphisms and Inferior Alveolar Nerve Block Success
The purpose of this study was to evaluate the association between COMT, MAOA, and SLC6A4 genetic polymorphisms and the success of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT07697300
- Testing
- Inferior Alveolar Nerve Block with 4% Articaine
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marmara University
Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
Effect of preoperative oral Ibuprofen on anesthetic efficacy of inferior alveolar nerve block with supplemental buccal and lingual infiltrations using articaine in mandibular molar teeth with irreversible pulpitis.
- Trial name
- NCT05927922
- Testing
- Oral Ibuprofen (Abbott, Egypt)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University