Clinical trials: Iron Metabolism Disorders
Iron Deficiency Anemia
Efficacious Iron for Iron Deficiency Anemia in Adults Aged ≥18 Years
Iron deficiency anemia (IDA) is a widespread condition affecting many people globally. Despite the many cases of IDA, there are few studies that compare the effectiveness of different types of iron supplements with a greater…
- Trial name
- NCT06303531
- Testing
- Ferrous Fumarate, Polysaccharide Iron, Ferrous Ascorbate
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- Dr. Anil K. Gupta Medicine Professional Corporation
Metabolic Diseases
Metabolic Disorders in Ultramarathon Runners During and After the Reunion Island Madmen's Diagonal
Acute consequences of ultramarathon running are still unknown as very little research has been done on the matter. The investigators will assess the consequences on the metabolism of runners in the ultramarathon Madmen's Diagonal…
- Trial name
- METARUN (NCT02275429)
- Testing
- Blood test
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pancreaticojuodenectomy
The Role of Intravenous Ferritin in Optimizing Postoperative Recovery Following Pancreaticoduodenectomy
Iron deficiency anemia is well known as a risk factor that worsens postoperative morbidity and patient prognosis. Several studies have shown that intravenous iron administration before surgery is effective in reducing the risk of…
- Trial name
- Ferritin (NCT06442111)
- Testing
- The intravenous ferritin group
- Volunteers
- 106 people
- Sponsor
- Seoul St. Mary's Hospital
Anemia, Iron Deficiency, Ulcerative Colitis
Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
The aim of the study is to compare the tolerability and efficacy of Sucrosomial Iron to Oral Iron Therapy in a randomized controlled trial for the treatment of Iron Deficiency Anemia in Ulcerative Colitis patients.
- Trial name
- NCT05225545
- Testing
- Sucrosomial Iron, Oral Iron
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- American University of Beirut Medical Center
Anemia, Iron-Deficiency
Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia
Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia.
- Trial name
- NCT00498511
- Testing
- upper gastrointestinal endoscopy, colonoscopy
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Insulin Resistance, Iron Overload
Cytochrome P450 2E1 and Iron Overload
The aim of the study is to determine, in patients presenting hepatic iron overload (genetic haemochtomatisis or dysmetabolic iron overload syndrome), the effects of venesection therapy on cytochrome P450 2E1 activity by comparing…
- Trial name
- NCT00138684
- Testing
- venesection
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Autosomal Dominant Hypophosphatemic Rickets
Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.
The purpose of the study is to gain a better understanding of the effect of iron on fibroblast growth factor 23 (FGF23) in the inherited disorder, autosomal dominant hypophosphatemic rickets (ADHR).
- Trial name
- NCT02233322
- Testing
- Iron
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Systolic Heart Failure, Iron Deficiency
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality
The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) extends the time-to-first-event of heart failure hospitalisations and cardiovascular (CV) death and reduces…
- Trial name
- FAIR-HF2 (NCT03036462)
- Testing
- Iron, Saline
- Where
- 51 sites in Germany, Hungary and 5 more
- Volunteers
- 1,105 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anemia, Iron Deficiency, Uterine Bleeding
IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department
The primary aim of this randomized trial is to assess the efficacy of IV Ferric Derisomaltose vs Oral Iron in the management of women with severe Iron Deficiency Anemia due to Uterine Bleeding in the emergency department.
- Trial name
- NCT05304442
- Testing
- Ferric Derisomaltose 1000 Mg in 10 mL INTRAVENOUS SOLUTION [Monoferric], Ferrous Sulfate 65 mg elemental iron (325 mg tablets)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Iron Deficiency Anemia Treatment
Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia
Lactoferrin (Lf) is a mammalian cationic iron binding glycoprotein belonging to the transferrin family which was discovered 70 years ago, and isolated simultaneously from human and bovine milks in 1960.
- Trial name
- NCT04267653
- Testing
- Lactoferrin Bovine, Ferrous Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Iron Overload, Hereditary Hemochromatosis
Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary Hemochromatosis
Brief Summary: This study was designed to explore a safe dose and characterize the preliminary safety and efficacy of ICL670 in adult patients with previously documented history of homozygous C282Y.
- Trial name
- NCT00395629
- Testing
- Deferasirox (ICL670)
- Where
- 18 sites in United States, Australia and 4 more
- Volunteers
- 49 people
- Sponsor
- Novartis Pharmaceuticals
Anaemia, Schistosomiasis Infection
Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment
The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).
- Conditions
- Anaemia, Schistosomiasis Infection, Malaria, Iron Deficiency
- Trial name
- NCT00414479
- Testing
- praziquantl, iron, ACT
- Where
- Kenya
- Volunteers
- 1,500 people
- Sponsor
- DBL -Institute for Health Research and Development
Fibroblast Growth Factor 23, Anemia
FGF23 and Cardiovascular Damage in Anemia With an Without Chronic Kidney Disease.
Anemia is associated with cardiovascular disease. Iron deficiency is usually induced in chronic kidney disease (CKD). In clinical studies, an inverse association between serum levels of iron and fibroblast growth factor 23…
- Conditions
- Fibroblast Growth Factor 23, Anemia, CKD
- Trial name
- NCT05356325
- Where
- Spain
- Volunteers
- 401 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Epithelial Ovarian Cancer, Anemia
Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients
This study tests the hypothesis that IV iron sucrose infusions given to iron deficient ovarian cancer patients prior to debulking surgery can improve pre-operative iron stores and decrease transfusion of packed red blood cells in…
- Conditions
- Epithelial Ovarian Cancer, Anemia, Iron Deficiency Anemia
- Trial name
- NCT03933813
- Testing
- Iron Sucrose
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Iron Status
The Relationship Between Iron Status, Cognitive Performance, Subjective Mood and Fatigue in Women of Reproductive Age.
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04257669
- Where
- United Kingdom
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Anemia, Iron Deficiency, Pregnancy Anemia
Iron Deficiency Anemia in the Second and Third Trimester of Pregnancy
Iron deficiency is the most frequent cause of anemia during pregnancy and of maternal blood transfusion during the post-partum period.
- Trial name
- PESO (NCT07163390)
- Testing
- Sideral Folico
- Volunteers
- 82 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Iron Deficiency Anemia
Impact and Evaluation of the Management of Iron Deficiency With or Without Anemia in Patients With Cancer
In oncology, anemia is a frequent symptom, leading to complication of patient management for, more or less, a long term but often poorly evaluated by medical teams. In oncology, anemia is induced by multiple causes.
- Trial name
- CAMARA (NCT03625661)
- Testing
- Ferinject
- Where
- France
- Volunteers
- 257 people
- Sponsor
- Institut Cancerologie de l'Ouest
Iron Deficiency Anemia
Ferrous Sulphate Supplement (V0355) in Women With Iron Deficiency Anaemia
The purpose of this study is to investigate the pharmacokinetics of serum iron after a single oral administration of 160 mg (2 tablets of 80 mg) V0355 in women with iron deficiency anaemia.
- Trial name
- NCT02518568
- Testing
- V0355
- Where
- 2 sites in Bulgaria, Romania
- Volunteers
- 29 people
- Sponsor
- Pierre Fabre Medicament
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
Retrospective Evaluation of the Effect of Iron (Fe) Infusion on Complications in Anemic Patients Undergoing Thoracotomy
In patients who underwent thoracotomy due to lung malignancy; It is desired to investigate whether there is a difference in terms of postoperative results between those with and without anemia, and those with iron deficiency…
- Trial name
- NCT05673161
- Testing
- iron
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Ankara University
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