Clinical trials: Iron Deficiency Anemia, open to volunteers
Varus-Derotation Osteotomy Surgery, Iron-deficiency Anemia
Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement Evaluation
Varus-derotation osteotomy (VDRO) is a surgery to prevent or address hip displacement in children. Many children having this surgery have cerebral palsy or other neuromotor disorders, who have a higher rate of malnutrition…
- Conditions
- Varus-Derotation Osteotomy Surgery, Iron-deficiency Anemia, Pelvic Osteotomy Surgery, Cerebral Palsy
- Trial name
- PORPOISE (NCT07095244)
- Testing
- Iron Supplement, Comprehensive Nutrition Management
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of British Columbia
Iron Deficiency Anaemia
The Use of Robot Assisted Magnetically Controlled Capsule Endoscopy in Patients With Iron Deficiency Anaemia
In this study the investigators will recruit patients who have already had an upper gastrointestinal (GI) tract endoscopy (OGD) and lower GI tract investigations which did not identify the source of iron deficiency anaemia, and…
- Trial name
- NCT07197424
- Testing
- Robot assisted magnetically controlled capsule endoscopy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Iron-deficiency
Imaging Intravenous Iron
The aim of this study is to track where the iron goes in different tissues in the hours, days and weeks after an intravenous iron infusion.
- Trial name
- NCT05609318
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Peritoneal Dialysis, Anaemia
Comparing High and Low Dose Iron Treatments for People on Peritoneal Dialysis: The PALaDIN Study
Chronic kidney disease affects a significant portion of the UK population, with approximately 3.5 million adults diagnosed. At its most severe stage, end-stage kidney disease, individuals require frequent dialysis treatment.
- Conditions
- Peritoneal Dialysis, Anaemia, Iron Deficiency, Anaemia
- Trial name
- PALaDIN (NCT06884280)
- Testing
- Monofer (iron isomaltoside 1000), Ferrous Sulfate
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Breath-holding Spell
Breath-holding Spells and Its Management Study
The goal of this prospective population-based study is to evaluate the new disease description and management guidelines for breath-holding spells in children (Hellström Schmidt et al, Acta Paediatrica 2024) below the age of 5…
- Trial name
- BAM (NCT06628271)
- Testing
- Guidelines
- Where
- 12 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Celiac Disease in Children, Anemia
Efficacy of Oral Sucrosomial Iron Supplementation in Children With Celiac Disease and Iron Deficiency or Anemia
Celiac disease in children is frequently associated with iron deficiency and/or iron deficiency anemia due to intestinal malabsorption and chronic inflammation.
- Conditions
- Celiac Disease in Children, Anemia, Iron Deficiencies
- Trial name
- NCT07563582
- Testing
- Sideral forte® VERUM drops
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Giannina Gaslini
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Iron-deficiency Anemia (IDA), Hemoglobin
Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia
The goal of this study is to compare ferrous salt and liposomal iron for the treatment of iron-deficiency anemia in adult women. The study will also evaluate how well each treatment is tolerated.
- Conditions
- Iron-deficiency Anemia (IDA), Hemoglobin, Iron Deficiencies, Adverse Effect
- Trial name
- IDA (NCT07556731)
- Testing
- Oral ferrous fumarate administered every 24 hours, Ferrous fumarate administered orally every 48 hours., Liposomal iron formulation.
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Hospital General de Mexico
Iron Deficiency Anemia
Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients
Postoperative anemia is common in cardiac surgery with cardiopulmonary bypass. Iron deficiency delays the recovery from postoperative anemia and may negatively affect the postoperative trajectory of cardiac surgery patients.
- Trial name
- AGE-ANEMIA (NCT04913649)
- Testing
- Ferric Derisomaltose 100 MG/ML, Sodium chloride
- Where
- 2 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- dr. P. Noordzij
Iron-deficiency Anemia (IDA), Pregnancy
Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate…
- Trial name
- NCT06492512
- Testing
- daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill, alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Southern Illinois University
Chronic Kidney Disease; Iron Deficiency Anemia
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Primary Objectives: To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemia (IDA) or who are at risk of development of IDA Secondary Objective: To…
- Trial name
- NCT03619850
- Testing
- Ferumoxytol, Iron sucrose
- Where
- 21 sites in United States, Hungary and 3 more
- Volunteers
- 129 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Iron Deficiency Anemia
A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects
This is a Phase 3, randomized, open-label, multicenter, study in male and female pediatric subjects (2 years to <18 years of age) with IDA, or felt by their clinician to be at risk of developing IDA.
- Trial name
- NCT03893045
- Testing
- ferumoxytol, Iron sucrose
- Where
- 15 sites in United States, Lithuania and 1 more
- Volunteers
- 75 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Anemia, Iron Deficiencies
Long-term Outcomes Sub-Study of Preoperative Combined Iron Therapy
This is a sub-study of the Preoperative Combined Iron Therapy trail in which some participants will be additionally randomized to combined iron supplementation or standarded treatment control to evaluate the impact on long-term…
- Conditions
- Anemia, Iron Deficiencies, Cardiac Surgery
- Trial name
- NCT06968936
- Testing
- Sucrose Iron，subcutaneous recombinant human erythropoietin，intravenous vitamin C, Routine perioperative management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anemia, Iron-Deficiency, Nutritional Deficiencies
Reducing Anemia Among Preconception Women in Nepal Through a Group Norm and Micronutrient Supplementation Intervention
Preconception micronutrient status (including anemia) is a critical determinant of maternal, newborn, and child health that remains undervalued in Nepal. However, providing micronutrient supplements (MMS) alone is not enough.
- Conditions
- Anemia, Iron-Deficiency, Nutritional Deficiencies, Adherence, Norms, Social
- Trial name
- Sumadhur (NCT06810440)
- Testing
- Sumadhur, Multiple micronutrient supplement MMS
- Where
- Nepal
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nutritional Status, Iron-deficiency
Assessing Dietary Intake of Selected Food Components Using Short Questionnaires
The aim of the study is to validate short questionnaires for assessing dietary intake of selected food components, with a focus on dietary fibre and iron.
- Conditions
- Nutritional Status, Iron-deficiency, Diet
- Trial name
- NutriPlant/FFQ (NCT07442305)
- Testing
- 5d-PD: Nutritional intakes using 24-h food recalls, KV-PV: Dietary fibre intake, KV-Fe: Iron intake
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease, Iron Deficiency Anaemia Due to Dietary Causes
The Role of Ferric Carboxymaltose in the Treatment of Pediatric Iron Deficiency Anemia in the Emergency Department
The goal of this project is to assess the feasibility, clinical effectiveness, and cost-effectiveness of IV iron therapy using ferric carboxymaltose (FCM) as a treatment for pediatric patients with iron deficiency anemia (IDA) in…
- Conditions
- Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease, Iron Deficiency Anaemia Due to Dietary Causes, Iron Deficiency Anemia Treatment, Iron Deficiency Anemia Secondary to IBD or Gastric Bypass
- Trial name
- ED-Heme FCM (NCT07414199)
- Testing
- Ferric Carboxymaltose (FCM), Ferrous Sulfate
- Volunteers
- 150 people
- Sponsor
- Children's Hospital of Orange County
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Iron Deficiency Anemia
Alternate-day Versus Daily Oral Iron Therapy in Children With Iron Deficiency Anaemia
The goal of this clinical trial is to find out whether Iron (III)-hydroxide polymaltose complex (IPC) given on an alternate-day schedule works as well as daily dosing in treating iron deficiency anaemia in children.
- Trial name
- NCT07391371
- Testing
- Alternate-day oral Iron (III)-hydroxide polymaltose complex, Iron (III)-hydroxide polymaltose complex - daily oral dosing Iron (III)-hydroxide polymaltose complex - alternate-day oral dosing
- Where
- 2 sites in Burma
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Medicine, Mandalay
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Pregnancy Related, Anemia, Iron Deficiency
Early Antenatal Support for Iron Deficiency Anemia
This is a randomized, controlled multi-site trial of iron therapy in pregnancy. The purpose of this research is to see if second trimester initiation of intravenous (IV) iron therapy is better than oral iron therapy for treatment…
- Conditions
- Pregnancy Related, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- EASI-A (NCT04278651)
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Thomas Jefferson University