Clinical trials: Iron Absorption
Anemia, Iron-Deficiency
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- FeGOS (NCT02666417)
- Testing
- Fortified maize porridge (MNP+iron), Fortified maize porridge (MNP+iron+GOS)
- Where
- Kenya
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency (Without Anemia)
Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption
Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism.
- Trial name
- INSECTE (NCT06822062)
- Testing
- Meal A, Meal B, Meal C
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences
Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
Effect of Altitude on Iron Absorption in Iron Depleted Women
One of the most common nutritional deficiencies worldwide is iron deficiency. Iron deficiency is considered the main cause of anaemia in developing countries, including those in South America.
- Conditions
- Iron Deficiency Anemia, Iron Deficiency (Without Anemia), Altitude Hypoxia
- Trial name
- PotatoAlt (NCT05500014)
- Testing
- Biofortified potato, not genetically modified
- Where
- 2 sites in Peru
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences
Iron-deficiency
The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements
Iron deficiency (ID) remains the most common global nutrient deficiency, with young women at high risk. Iron supplements are first line treatment for ID but absorption is often low.
- Trial name
- NCT04194255
- Testing
- ferrous fumarate, ferrous fumarate + 15 g GOS, ferrous fumarate + 15 g FOS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Iron Metabolism Disorders
The Effect of Genetic Variation in TMPRSS6 Gene (SNP rs855791) on Oral Iron Absorption: an Iron Stable Isotope Study
Iron deficiency is considered the most common nutritional deficiency worldwide and affects children and women in both non-industrialized as well as industrialized countries.
- Trial name
- NCT03317873
- Testing
- Testmeal A, Testmeal B
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiencies
Iron Absorption From Naturally Dephytinized Legumes
Consumption of less meat and more plant-based protein can greatly reduce the negative impact of food production on the environment. Studies show that vegan diets can decrease greenhouse gas emissions, land use, and water.
- Trial name
- LINDA (NCT06032832)
- Testing
- soy protein concentrate-meat analog, soy protein concentrate-meat analog_dephytinization, pork meat
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Iron Absorption
Iron Absorption in Vegetarian Children
Few areas are more controversial in pediatric nutrition than the role of a vegetarian diet for children. Advocates make strong health claims whereas others have expressed safety concerns, especially regarding iron nutrition.
- Trial name
- NCT01489007
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron-deficiency, Iron Deficiency Anemia
Effects of Enhancers and Inhibitors on Absorption From Iron Supplements
Iron deficiency (ID) is a major public health problem worldwide and oral iron supplementation can be an effective strategy to treat and prevent ID.
- Trial name
- NCT05414474
- Testing
- Reference, Ascorbic acid (AA) 500 mg, Ascorbic acid (AA) 80 mg
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Iron Absorption From Iron Fortified Extruded Rice Co-fortified With Various Solubilizing Agents
Food fortification is regarded as a safe and cost-effective approach to counteract and prevent iron deficiency. Rice is a staple food for millions of people living in regions where iron-deficiency anaemia is a significant public…
- Trial name
- NCT03703739
- Testing
- Reference meal 1, Reference 2, Test meal A
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia
The Optimization of Bioavailability From Iron Supplements: Study 1
Iron deficiency (ID) with or without anaemia (IDA) is a major public health problem worldwide, especially in women of reproductive age and young children.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02175888
- Testing
- Daily administration of 60 mg iron in form of ferrous sulphate capsules for 14 consecutive days, Administrations of 60 mg iron in form of ferrous sulphate capsules on every second day for 28 days
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron-Deficiency
Tea Consumption and Iron Bioavailability in Women Using a Stable Isotope
The purpose of this study is to investigate the inhibition effect of tea consumption on non haem iron absorption with the use of an iron tracer.
- Trial name
- NCT02365103
- Testing
- Test meal I (given with water), Test meal II (simultaneously with tea), Test meal III (1 hour after test meal)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Enrichment of Blood
Iron Absorption From Biofortified Beans With Different Levels of Phytic Acid
Iron deficiency and iron deficiency anemia are among the major health problems in the developing world. Women of childbearing age as well as children are the most vulnerable population groups.
- Trial name
- NCT01521273
- Testing
- Bean varieties
- Where
- Rwanda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Absorption, Iron Absorption
Zinc and Iron Absorption From Common Beans in Young Adult Women
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and…
- Trial name
- NCT06327529
- Testing
- SER 118, LMP 1001, LPA 586
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iron Deficiency
Malaria and the Safety of Iron Supplements and Iron Fortification
The primary study hypothesis of the investigators is that administration of an iron supplement between meals at a dose like that used in the Pemba trial (~1 mg Fe/kg) during P.
- Trial name
- MIA (NCT01156896)
- Testing
- Ferrous sulfate
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron Absorption
Iron Long-Term Labelling Study Benin
Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making…
- Trial name
- NCT02979080
- Testing
- Eisensulfat LOMAPHARM 50 mg
- Where
- 2 sites in Benin
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Anemia, Iron-deficiency
The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants
Effective and safe strategies to deliver iron to infants and young children in Sub-Saharan Africa are urgently needed. One potential strategy to improve safety of iron fortification is to limit the total amount of unabsorbed iron…
- Trial name
- FeHMOGOS (NCT04163406)
- Testing
- ferrous fumarate, ferrous fumarate + GOS, ferrous fumarate + HMOs
- Where
- Kenya
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Anemia, Iron Deficiency, Iron Overload
Ethnic Differences in Iron Absorption (FeGenes)
This study aims to; 1) investigate population differences in iron absorption between East Asians and Northern Europeans; 2) assess population differences in hormonal and biochemical determinants of Fe absorption between East…
- Trial name
- FeGenes (NCT04198545)
- Where
- 2 sites in United States
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Cornell University
Gut -Microbiota, Inflamation
Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren
The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.
- Conditions
- Gut -Microbiota, Inflamation, Iron Absorption
- Trial name
- NCT07439185
- Testing
- Cricket and Black Soldier Fly Larvae-fortified Cracker, Rice and Corn Cracker
- Where
- Madagascar
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Cornell University
Vitamin A Deficiency
Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
The primary purpose of this study is to determine whether daily consumption of orange-fleshed sweet potatoes increases the vitamin A status of Bangladeshi women of reproductive age.
- Trial name
- NCT00453648
- Testing
- White-fleshed sweet potatoes, Orange-fleshed sweet potatoes (boiled), Orange-fleshed sweet potatoes (fried)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Davis