Clinical trials: Iron Absorption
Iron-deficiency
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2)
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products.
- Trial name
- Sustironable2 (NCT05328141)
- Testing
- Bread and butter, X.gideon, X.gideon with ascorbic acid
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides
The co-primary objectives of this study are: 1) to investigate the effect adding a synbiotic (combination of a pre-and probiotic) to iron-fortified follow-up formula (FUF) on iron bioavailability, and 2) to investigate the effect…
- Trial name
- NCT04774016
- Testing
- Test formula A without added pre- and pro-biotic, Test formula B with synbiotic, Test formula C with HMOs
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Anemia, Iron Deficiency (Without Anemia)
The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females
The goal of this study is to identify how well a fish-based iron supplement is absorbed and to learn how many, if any, digestive related side effects are caused by ingesting the supplement.
- Conditions
- Anemia, Iron Deficiency (Without Anemia), Iron Absorption
- Trial name
- NCT07199244
- Testing
- marine-based heme iron
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Iron-deficiency
Iron Absorption From Encapsulated Iron Sulphate in Microspheres
Food fortification has shown to be efficacious to alleviate the burden of micronutrient deficiencies. Ensuring the bioavailability of iron and maintaining the sensory quality and stability of the fortified food and other added…
- Trial name
- NCT03332602
- Testing
- free FeSO4, free FeSO4 and empty microspheres, free FeSO4 and hylauronic acid
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency Anemia
IHAT Absorption Kinetics
At MRC Human Nutrition Research, the investigators have developed an engineered analogue of the ferritin-core for safe and effective iron supplementation.
- Trial name
- NCT02498886
- Testing
- IHAT, Ferrous sulphate
- Where
- The Gambia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Iron Deficiency, Anemia
The Optimization of Bioavailability From Iron Supplements: Study 1
Iron deficiency (ID) with or without anaemia (IDA) is a major public health problem worldwide, especially in women of reproductive age and young children.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02175888
- Testing
- Daily administration of 60 mg iron in form of ferrous sulphate capsules for 14 consecutive days, Administrations of 60 mg iron in form of ferrous sulphate capsules on every second day for 28 days
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Sleep, Inadequate, Energy Deficit
The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity
This longitudinal study will examine the effects of repeated bouts of operational stress and limited recovery on integrated MPS, whole-body protein balance, iron absorption, and aerobic performance.
- Conditions
- Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
- Trial name
- REP DEF (NCT06784544)
- Testing
- Operational Stressors
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Iron Absorption
Iron Long-Term Labelling Study Benin
Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making…
- Trial name
- NCT02979080
- Testing
- Eisensulfat LOMAPHARM 50 mg
- Where
- 2 sites in Benin
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Iron Deficiency
Absorption, Stable Isotope Appearance and Non-transferrin-bound Iron (NTBI) Profile From NaFeEDTA and Ferrous Sulphate
Several iron compounds are used for fortification, including ferrous sulphate and NaFeEDTA. The absorption profile of these may differ because of differences in their dissolution in the gastrointestinal tract and in their…
- Trial name
- SIA (NCT01053442)
- Testing
- Porridge fortified with either NaFeEDTA, FeSO4
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Obesity, Iron Deficiency
Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity
Young women living with obesity (OB) have a greater risk of developing iron deficiency. Plus, the risk of anemia and/or ID in young women living with overweight (OW) and obesity (OB) is further increased by inadequate dietary…
- Conditions
- Obesity, Iron Deficiency, Inflammation
- Trial name
- RAYON (NCT07081152)
- Testing
- Ferrous sulfate
- Where
- South Africa
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Linda Malan
Iron-deficiency
The Effect of Lactoferrin and Dosing Regimen on Iron Absorption From a Maize-based Porridge in Kenyan Infants
The purpose of this study is to measure iron absorption from maize-based porridge fortified with either apo-lactoferrin, holo-lactoferrin or ferrous sulfate and to test whether there is an effect of these.
- Trial name
- NCT03617575
- Testing
- apo-Lactoferrin, holo-Lactoferrin, FeSO4
- Where
- Kenya
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Enrichment of Blood
Iron Absorption From Biofortified Beans With Different Levels of Phytic Acid
Iron deficiency and iron deficiency anemia are among the major health problems in the developing world. Women of childbearing age as well as children are the most vulnerable population groups.
- Trial name
- NCT01521273
- Testing
- Bean varieties
- Where
- Rwanda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pregnancy
Encapsulated Calcium Absorption in Pregnancy
This study will enroll at least 60 pregnant women in a randomized cross-over study in Dhaka, Bangladesh. Each participant will be randomized to one of 3 calcium doses: 500 mg, 1000 mg, 1500 mg elemental Ca per day.
- Trial name
- ENCAP (NCT01678079)
- Testing
- Encapsulated Calcium, Non-capsulated Calcium
- Where
- 4 sites in United States, Bangladesh and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy, Nutrition, Healthy
Non-heme Iron Absorption From Single Meals of Fava Bean Protein, Beef Protein and Cod Protein
The aim of this study is to investigate the non-heme iron absorption from single meals of texturized fava bean protein, which has been suggested as a protein source suitable for replacement of meat, compared to the non-heme iron…
- Trial name
- NCT05392816
- Testing
- Single meal non-heme iron absorption
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Anemia, Iron-Deficiency
Tea Consumption and Iron Bioavailability in Women Using a Stable Isotope
The purpose of this study is to investigate the inhibition effect of tea consumption on non haem iron absorption with the use of an iron tracer.
- Trial name
- NCT02365103
- Testing
- Test meal I (given with water), Test meal II (simultaneously with tea), Test meal III (1 hour after test meal)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Nutritional Deficiency
Bioavailability of Zinc and Iron From a Whey-based Protein Supplement Consumed With a Habitual Plant-based Diet
Bioavailability of iron and zinc from habitual plant-based diets consumed by young children in Mexico is low due to the high phytate content.
- Trial name
- NCT02208622
- Testing
- Study 1: Whey Supplement Day 1, Study 1: Whey Supplement Day 2, Study 2: Whey Supplement
- Where
- 2 sites in United States, Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency
Iron Interventions and Non-transferrin-bound Iron (NTBI) in Women
The overall goal of this research is to develop safe and effective iron interventions that can be administered without production of plasma non-transferrin-bound iron (NTBI: iron in the systemic circulation not bound to the…
- Trial name
- NTBIwomen (NCT01404533)
- Testing
- Ferrous sulfate
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia
A Test of Iron Malabsorption in Patients With Iron Deficiency Anemia
The objective of the study is to develop a simple, noninvasive test for evaluation of iron absorption as a tool to determine the cause of iron deficiency anemia.
- Trial name
- NCT00399191
- Testing
- stable isotope of iron, dysprosium
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Low Iron Stores
The Effect of Lactobacillus Cultures on Iron Bioavailability.
The purpose of this study is to determine the effect of a lactic acid fermented oat gruel on iron absorption in the upper and lower part of the intestine, respectively.
- Trial name
- NCT00283491
- Testing
- Active Lactobacillus plantarum 299v, Inactive Lactobacillus plantarum 299v
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Iron Deficiency
Iron Absorption From GDS Capsules II
Slow release iron capsules containing ferrous sulfate have been designed based on the gastric delivery system. Iron absorption from those capsules administered with and without meals will be measured using stable iron isotopes.
- Trial name
- NCT01985386
- Testing
- GDS capsule with meal, Ferrous sulfate with meal
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology