Clinical trials: Iodine Deficiency
Iodine Deficiency, Infant Development
Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development
Rationale: In regions of severe endemic goiter, the adverse effects of in utero iodine deficiency on neuromotor development are well established: randomized controlled trials of iodine supplements given to iodine deficient…
- Trial name
- MITCH (NCT00791466)
- Testing
- Iodine
- Where
- 2 sites in India, Thailand
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iodine Deficiency
Estimating Usual Iodine Intake From Spot Urinary Iodine Concentrations
The overall objective of this study is to develop a reliable method to obtain habitual iodine intakes from spot urinary iodine concentration (UIC) and to assess the prevalence of inadequate iodine intake in school-age children…
- Trial name
- ITURN (NCT03602404)
- Where
- 2 sites in Papua New Guinea, Russia
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Prevalence of Iodine Deficiency in Remote Communities of Haiti
Haiti is one of the few remaining countries that is at risk of iodine deficiency disorders. In the 2018 survey, iodized salt was found in <20% of households and iodine excretion from non-pregnant and pregnant women suggested…
- Trial name
- NCT05275452
- Testing
- No intervention
- Where
- Haiti
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hypothyroidism, Pregnancy Related
Normal Range of TSH and FT4 in Pregnancy
Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Hypothyroidism, Pregnancy Related, Thyroid, Dysfunction
- Trial name
- NRTSHTURKEY (NCT04860622)
- Testing
- Serum thyroid function tests
- Where
- Turkey (Türkiye)
- Volunteers
- 528 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Iodine Deficiency
Variability of Daily Iodine Intake: The Effects of Intra- and Inter-individual Variability in Iodine Nutrition Studies
Iodine status in populations is assessed using urinary iodine concentration (UIC) measured in spot urine samples. The iodine intake is classified as deficient, sufficient, or excessive iodine based on the median UIC (mUIC).
- Trial name
- VIOLET (NCT03731312)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Climat Impact on Urinary Iodine Concentration
Urinary iodine concentration (UIC) is the recommended biomarker of iodine status in populations. Yet, the influence of climate on UIC remains unclear.
- Trial name
- LION (NCT03215680)
- Testing
- Climate
- Where
- 2 sites in South Africa, Tanzania
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Caribbean Island Urinary Iodine Survey 2018
Many of the Caribbean island nations have no data on iodine status in their populations. Iodine deficiency in children can reduce IQ but can be easily corrected through a program of salt iodization.
- Trial name
- CRUISE (NCT04388540)
- Where
- 10 sites in Antigua and Barbuda, Barbados and 8 more
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency, Pregnancy Related
Assessment of Dried Blood Spot Thyroglobulin and Urinary Iodine Concentration in Pregnant Women
To avoid iodine deficiency and its consequences in pregnant women and their offspring, women should reach a sufficient iodine intake long before conception.
- Trial name
- STRIPE (NCT03176706)
- Testing
- no intervention
- Where
- New Zealand
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pregnancy, Iodine Deficiency
Iodine Nutrition During Pregnancy and Related Neonatal Physical Development
Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status.Our overall aim is to monitor iodine status of pregnant women in China, and…
- Trial name
- NCT02586220
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- qingya tang
Iodine Deficiency Goiter, Infant Development
Community Salt Testing and Relation of Iodine Intake to Visual Information Processing of Ethiopian Infants
This study evaluated efficacy of iodized salt for mothers and their six-month-old infants' thyroid hormones and visual information processing.
- Trial name
- NCT03889431
- Testing
- Iodine capsule, Iodized Salt
- Where
- Ethiopia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Iodine Excess in Pregnancy, Selenium Excess in Pregnancy
The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease
Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with…
- Conditions
- Iodine Excess in Pregnancy, Selenium Excess in Pregnancy, Iodine Deficiency in Pregnancy, Selenium Deficiency in Pregnancy
- Trial name
- NCT03761602
- Testing
- Not applicable (for observational studies)
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Rongrong Li
Dietary Intervention, Pregnancy Jail
Group Education to Improve the Iodine Nutrition in Pregnancy: Cluster Randomized Trial
The purpose of this study is to assess the effectiveness of individual education versus group education about dietary habits and iodine supplementation to decrease iodine deficiency in pregnant women
- Conditions
- Dietary Intervention, Pregnancy Jail, Iodine Deficiency
- Trial name
- NCT01301768
- Testing
- Group Education
- Where
- Spain
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pregnancy, Thyroid Autoimmune Disease
Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy
In 1994, the WHO and UNICEF Joint Committee on Health Policy recommended Universal Salt Iodization as a safe, cost-effective and sustainable strategy to ensure sufficient intake of iodine by all individuals.
- Conditions
- Pregnancy, Thyroid Autoimmune Disease, Iodine Deficiency, Selenium Deficiency
- Trial name
- NCT03377218
- Testing
- Iodine, Iodine + Selenium
- Where
- Latvia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Iodine-Deficiency; Hypothyroidism
Iodine Status in Pregnant Women in Israel
Worldwide Data suggest that Iodine deficiency is a concern among healthy pregnant women. Thus, screening first trimester healthy pregnant women for iodine status is of clinical value for mother and child as iodine deficiency…
- Trial name
- NCT03120221
- Testing
- Urine sample for iodine measurement
- Where
- 2 sites in Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Iodine Deficiency, Nutritional Requirements
An Iodine Balance Experiment
A 4-week study was conducted in 25 Chinese euthyroid women. Unified diets with different iodine contents (cooked with non-iodized salt or iodized salt) were provided in two different periods.
- Trial name
- NCT03279315
- Testing
- iodized table salt, non-iodized table salt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Iodine Deficiency Disorders
RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
In this study, two intervention strategies to address iodine deficiency and prevent iodine deficiency disorders in breast-fed weaning infants will be evaluated in a mild to moderate iodine-deficient population in Zamboanga del…
- Trial name
- NCT02421653
- Testing
- MNP90, MNP45, IODISED OIL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hypothyroidism, Subclinical Hypothyroidism
Thyroid Disorders in Malaysia: A Nationwide Multicentre Study
This will be a population based study looking at the prevalence of thyroid disorders in Malaysia (including hypo- and hyperthyroidism, subclinical hypo- or hyperthyroidism) and its association with different ethnicity and iodine…
- Conditions
- Hypothyroidism, Subclinical Hypothyroidism, Hyperthyroidism, Subclinical Hyperthyroidism
- Trial name
- MyEndo-Thyroid (NCT02190214)
- Volunteers
- 2,498 people, healthy volunteers welcome
- Sponsor
- International Islamic University Malaysia
Dietary Iodine Deficiency, Thyroid; Functional Disturbance
Serum Thyroglobulin as a Marker of Iodine Status During Pregnancy
The purpose of the investigation is to assess iodine status of pregnant women at week 16 of gestation targeting serum thyroglobulin as a biomarker of iodine deficiency.
- Trial name
- NCT02927119
- Testing
- iodine
- Volunteers
- 189 people
- Sponsor
- University of Debrecen
Iodine Deficiency, Goiter
The Effects of Iodized Salt on Cognitive Development in Ethiopia
Many school children in Ethiopia and their mothers are known to be iodine deficient. Prevalence in the Amhara region is around 29%.
- Conditions
- Iodine Deficiency, Goiter, Cretinism
- Trial name
- NCT01349634
- Testing
- Iodized salt
- Where
- Canada
- Volunteers
- 5,704 people, healthy volunteers welcome
- Sponsor
- McGill University
Iodine Deficiency
Salt Iodization: Meeting the Needs of Pregnancy, Lactation and Infancy
The purpose of this study is to determine whether universal salt iodization (USI) meets the iodine requirements of pregnant women, lactating women and infants.
- Trial name
- SIMPLIFY (NCT02196337)
- Where
- 4 sites in China, Croatia and 2 more
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology