Clinical trials: Intubation Conditions
Respiration and the Airways With Laryngeal Masks
Blind Tracheal Intubation Through Supraglottic Airway Devices
Tracheal intubation is considered the gold standard for protecting the airway. As the supraglottic airway devices (SADs) could be inserted without laryngoscopy, so that SADs with different designs and safety issues could be used…
- Trial name
- NCT05624073
- Testing
- Air-QTM Blocker, LarySealTM Pro
- Where
- 2 sites in Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypoxemia, Airway Management
Comparison of High-Flow Nasal Cannula and Tight Face Mask for Maintaining Oxygenation During Rapid Sequence Induction
This prospective randomized controlled trial aims to compare the effectiveness of High-Flow Nasal Cannula (HFNC) versus Tight Face Mask (TFM) in maintaining oxygenation during rapid sequence induction (RSI) for endotracheal…
- Conditions
- Hypoxemia, Airway Management, Endotracheal Intubation, Rapid Sequence Induction
- Trial name
- NCT07723430
- Testing
- High-Flow Nasal Cannula, Tight Face Mask
- Volunteers
- 290 people
- Sponsor
- Khyber Teaching Hospital
Pneumonia, Ventilator-Associated, Critical Illness
Intubation and Extubation Over 48 Hours Mechanical Ventilation
The purpose of this study is to determine how often ventilator associated pneumonia happens in the current intensive care units, and how types of endotracheal tube affect its occurrence.
- Trial name
- INDEX48 (NCT01123681)
- Testing
- Choice of endotracheal tube
- Where
- 6 sites in Japan
- Volunteers
- 200 people
- Sponsor
- Okayama Research Investigator Organizing Network
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Critical Illness
Clinical Trial on Individual Characteristics Affecting Pain Drug Therapy in Neonates
Children differ from adults with respect to growth and development but also immaturity of various pharmacological mechanisms. Dosing schemes in children are usually derived in an empirical manner from clinical trials in adult…
- Trial name
- NeoPopGen (NCT02426463)
- Testing
- propofol, oxycodone
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Emergencies
Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation
Mivacurium can be considered as an optimal choice for muscle relaxation in short duration surgeries, as butyrylcholinesterase can rapidly and reliably degrade this benzylisoquinoline muscle relaxant in vivo.
- Trial name
- RSI (NCT06072534)
- Testing
- "Mivacurium Chloride"
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Tracheal Intubation, Infection
Comparison of VieScope vs. Macintosh Laryngoscope for Intubation in Level Cpersonal Protective Equipment Conditions
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and…
- Conditions
- Tracheal Intubation, Infection, Projection
- Trial name
- NCT04363775
- Testing
- The standard Macintosh laryngoscope, The Vie Scope laryngoscope
- Where
- Poland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Post Operative Sore Throat, Dysphagia
Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique
The purpose of this study is to test whether the incidence of sore throat and other tracheal co-morbidities such as dysphagia and hoarseness can be lessened by use of a cuff manometer at the beginning of surgery to inflate to the…
- Conditions
- Post Operative Sore Throat, Dysphagia, Hoarseness
- Trial name
- NCT01305265
- Testing
- cuff manometer
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intubation; Difficult or Failed, Obesity, Morbid
The Effect of Endotracheal Tube With Stylet in Morbidly Obese Patients
The investigators aimed to compare the effects of using enotracheal tube with stylet versus endotracheal tube alone in morbidly obese patients undergoing sleeve gastrectomy.
- Trial name
- NCT06405672
- Testing
- Endotracheal tube with stylet, Endotracheal tube alone
- Volunteers
- 80 people
- Sponsor
- Antalya Training and Research Hospital
Intensive Care Unit ICU, Intubation
The Effects of Endotracheal Suctioning on Pain and Serum Markers
The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients.
- Conditions
- Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation
- Trial name
- NCT06692400
- Testing
- endotracheal tube suctioning
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Loma Linda University
Nasotracheal Intubation
Effect of Nose Selection Using Rhnoscope on Epistaxis of Nasotracheal Intubation
Rhinoscope is useful to exam intranasal structure. This information could be utilized to select more suitable nose for nasotracheal intubation.
- Trial name
- NCT04164836
- Testing
- rhinoscope
- Where
- South Korea
- Volunteers
- 182 people
- Sponsor
- Ajou University School of Medicine
Minimally Sedated Patient Undergoing Colonoscopy
Comparing Maximal and Half-maximal Suction Pressure Applied During Water Exchange in Colonoscopy
This prospective, randomize, controlled trial will compared maximal to half-maximal suction pressure applied during water exchange in patients undergoing minimally sedated colonoscopy.
- Trial name
- NCT01948284
- Testing
- half-maximal pressure, maximal pressure, Suction Unit
- Where
- Taiwan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Infections, Hospital, Ventilator-Associated Pneumonia
Strategies To Prevent Pneumonia 2 (SToPP2)
Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated critically ill patients. The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is…
- Conditions
- Infections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
- Trial name
- SToPP2 (NCT00893763)
- Testing
- Pre-intubation CHX, Control
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- University of South Florida
Pressure Injury, Dysphonia
Initial Increase in Cuff Pressure in Anterior Cervical Spinal Surgery
When the retractor blades oped and is positioned to provide the surgical access in the anterior cervical spine surgery, it cause the trachea to deviate laterally and pose pressure on the tissue between the retractor and the…
- Conditions
- Pressure Injury, Dysphonia, Dysphagia
- Trial name
- NCT03240042
- Testing
- nasotracheal intubation, orotracheal intubation
- Where
- Taiwan
- Volunteers
- 118 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intubation Complication
Neurologic Function Post Intubation
The frequency of oxygen desaturation during emergency intubation is not uncommon. However, the significance and clinical sequalae of hypoxia during emergency intubation in critically ill, non-trauma patients is not known.
- Trial name
- NeuroHypoxia (NCT05412823)
- Where
- Saudi Arabia
- Volunteers
- 1,000 people
- Sponsor
- King Abdulaziz University
Nasal Obstruction, Arthrosis
Role of Airtraq Mobile to Improve Intubation Conditions With Airtraq
Airtraq sp has been proven effective for intubating patients presenting with difficult airway. The Airtraq sp allows visualisation of the tracheal inlet only for the intubator.
- Trial name
- AirtraqMob (NCT02510924)
- Testing
- Tracheal intubation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Airway Complication of Anesthesia, Peroperative Complication
Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
Background and Objective: Airway control is a condition that should be evaluated primarily in anesthesia practice in the pediatric age group.
- Conditions
- Airway Complication of Anesthesia, Peroperative Complication, Intraoperative Hypertension, Tachycardia, Sinus
- Trial name
- Laryngoscopy (NCT04677894)
- Testing
- Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ordu University
Colonoscopy
Factors Predict Difficult Colonoscopy Before the Procedure: Prospective Registry Study
In this study, the investigators aim to evaluate the relationship between cecal intubation time during colonoscopies and factors such as the patient's age, body mass index, history of constipation, Wexner constipation score…
- Trial name
- NCT06151275
- Where
- Turkey (Türkiye)
- Volunteers
- 915 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Adult Patients, Requiring Intubation
Lung MORphological Modifications Evaluated by Electrical Impedance Tomography During Preoxygenation for the Intubation of Hypoxemic Patients: Comparison of Standard Oxygenation, High Flow Nasal Oxygen Therapy, and NonInvasive Ventilation (MORPHEIT Study, an Ancillary Study of PREONIV Trial)
Prospective, randomized clinical multicentric study, in ICU, during preoxygenation for the intubation of hypoxemic patients. Electrical impedance tomographic evaluation of lung morphology variations according to the…
- Conditions
- Adult Patients, Requiring Intubation, Hypoxemia (Defined by PaO2/FiO2( Fraction of Inspired Oxygen) Below 200), Patient Covered by French Health Care System
- Trial name
- MORPHEIT (NCT03282331)
- Testing
- Standard oxygenation, High flow nasal oxygenation, noninvasive ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Intubation;Difficult
Awake Nasal Fiber-optic Intubation of Severely Obese Patients in Lateral Position
Airway management in severely obese patients remains a challenging issue for anesthetists and may lead to life-threatening situations.
- Conditions
- Anesthesia, Intubation;Difficult, Intubation; Difficult or Failed, Anesthesia Intubation Complication
- Trial name
- NCT04779528
- Testing
- Fiberoptic intubation in supine position., Fiberoptic intubation in lateral position.
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan