Clinical trials: Intubation Complication
Anesthesia, Airway Complication of Anesthesia
Two Neck Ultrasound Measurements as Predictors of Difficult Laryngoscopy
Background: Unpredictable laryngoscopic difficulty remains a dramatic challenge for anaesthesiologists. Ultrasound (US) based airway assessment has been recently proposed as a useful tool in adjunct to clinical methods, but to…
- Conditions
- Anesthesia, Airway Complication of Anesthesia, Difficult Intubation
- Trial name
- NCT03547193
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Università Politecnica delle Marche
Infant, Newborn, Diseases, Other Preterm Infants
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24…
- Conditions
- Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth
- Trial name
- SUPPORT (NCT00233324)
- Testing
- Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%
- Where
- 22 sites in United States
- Volunteers
- 1,316 people
- Sponsor
- NICHD Neonatal Research Network
Intubation Complication
Effectiveness of Cricoid and Paratracheal Pressures for Occluding Esophagus
Comparing the effects of 'Cricoid pressure' or 'Paratracheal pressure' during direct laryngoscopy
- Trial name
- NCT03992950
- Testing
- Maneuvers for occluding esophagus
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- SMG-SNU Boramae Medical Center
Infections, Hospital, Ventilator-Associated Pneumonia
Strategies To Prevent Pneumonia 2 (SToPP2)
Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated critically ill patients. The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is…
- Conditions
- Infections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
- Trial name
- SToPP2 (NCT00893763)
- Testing
- Pre-intubation CHX, Control
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- University of South Florida
Intubation Complication
Neurologic Function Post Intubation
The frequency of oxygen desaturation during emergency intubation is not uncommon. However, the significance and clinical sequalae of hypoxia during emergency intubation in critically ill, non-trauma patients is not known.
- Trial name
- NeuroHypoxia (NCT05412823)
- Where
- Saudi Arabia
- Volunteers
- 1,000 people
- Sponsor
- King Abdulaziz University
Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage
Ultrasound Measurements of Circular Cartilage Transverse Diameter
This study with children under 1 age of elective surgery as the research subjects, according to the cross diameter, compared with the traditional method of empirical catheter model, analyze the success rate, completion time of…
- Conditions
- Ultrasound Therapy; Complications, Transverse Diameter of Cricoid Cartilage, Endotracheal Intubation, Children
- Trial name
- NCT05273294
- Testing
- Portable color Doppler ultrasound system
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shengjing Hospital
Respiratory Failure, Intubation
Efficiency of the King Vision Video Laryngoscope
The investigators studied the efficiency of Macintosh laryngoscope and the King Vision video laryngoscope in adult patients scheduled for general anesthesia.
- Trial name
- NCT02482870
- Testing
- Macintosh laryngoscope, King Vision video laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Airway Complication of Anesthesia, Peroperative Complication
Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
Background and Objective: Airway control is a condition that should be evaluated primarily in anesthesia practice in the pediatric age group.
- Conditions
- Airway Complication of Anesthesia, Peroperative Complication, Intraoperative Hypertension, Tachycardia, Sinus
- Trial name
- Laryngoscopy (NCT04677894)
- Testing
- Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ordu University
Acute Respiratory Failure, Intubation
Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU
Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications.
- Conditions
- Acute Respiratory Failure, Intubation, Intubation; Difficult or Failed, Videolaryngoscopy
- Trial name
- INVIBLADE (NCT06322719)
- Testing
- Hyperangulated blade videolaryngoscope, Macintosh blade videolaryngoscope
- Where
- 29 sites in Spain
- Volunteers
- 1,036 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Anesthesia, Intubation;Difficult
Awake Nasal Fiber-optic Intubation of Severely Obese Patients in Lateral Position
Airway management in severely obese patients remains a challenging issue for anesthetists and may lead to life-threatening situations.
- Conditions
- Anesthesia, Intubation;Difficult, Intubation; Difficult or Failed, Anesthesia Intubation Complication
- Trial name
- NCT04779528
- Testing
- Fiberoptic intubation in supine position., Fiberoptic intubation in lateral position.
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Anesthesia Intubation Complication
Cuff Pressure in Patients: Manometer vs Invasive Pressure Monitoring Setup
This is a prospective study looking at ways to measure the cuff pressure of cuffed endotracheal tubes (ETTs). We will be comparing a hand-held manometer (MM) to the transducer of an invasive pressure monitoring setup (IPMS)…
- Trial name
- NCT01885793
- Testing
- Cuffed endotracheal tube
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Senthil G. Krishna
Airway Complication of Anesthesia, Intubation;Difficult
Pediatric Videolaryngoscopic Intubation and Difficult Airway Classification
The study's primary aim is to develop and validate a multivariable diagnostic model for the prediction of difficult videolaryngoscopy (the 'PeDiAC classification') in children undergoing general anesthesia with tracheal…
- Conditions
- Airway Complication of Anesthesia, Intubation;Difficult, Anesthesia, Laryngoscopy
- Trial name
- PeDiAC (NCT04844723)
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Intubation Complication
Comparison of First Attempt Success Based on Endotracheal Tube Type During Videolaryngoscope-guided Intubation Without Stylet
Patients are randomly assigned to either the oral RAE tube group (Group O) or the reinforced tube group (Group R). In both groups, tracheal intubation is performed using a videolaryngoscope without a stylet, and the first-attempt…
- Trial name
- NCT07682480
- Testing
- endotracheal tube
- Volunteers
- 246 people
- Sponsor
- Seoul National University Hospital
Anesthesia Intubation Complication
The Comparison of Glidescope® and the Direct Laryngoscopy in the Insertion of the Double Lumen Endotracheal Tube
Double-lumen bronchial tube (DLT) had been demonstrated to benefit for thoracic surgery and also played an important role to achieve one-lung ventilation (OLV) for exploring the surgical fields.
- Trial name
- Glidescope (NCT01424605)
- Testing
- DLT intubation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Mechanical Ventilation Complication, Acute Respiratory Failure
Non-invasive Respiratory Monitoring During SBT
Spontaneous breathing trials (SBTs) assess readiness for extubation, yet the use of conventional parameters used to establish weaning success may be elusive, especially in high-risk patients.
- Conditions
- Mechanical Ventilation Complication, Acute Respiratory Failure, Re-intubation Rate
- Trial name
- NCT05295186
- Where
- 2 sites in Italy
- Volunteers
- 238 people
- Sponsor
- University of Bari
Emergence Delirium, Anesthesia
Emergence Delirium、fBFI-ENO Score (Extraversion + Neuroticism - Openness) Based on the Fast Big Five Personality Scale-10、An Adult Patient With ASAI-III Who is Scheduled for Elective Non-cardiac Surgery and is to Undergo General Anesthesia With Tracheal Intubation
The aim of this study is to verify the generalizability of the fBFI-ENO score (extraversion + neuroticism - openness) constructed based on the Rapid Big Five Personality Scale - 10 across different genders, ages, and surgical…
- Trial name
- NCT07775768
- Volunteers
- 880 people
- Sponsor
- Hongjiao Xu
Anesthesia Intubation Complication
Alfentanil and the Elimination of Sympathetic Responses to Tracheal Intubation During Rapid Sequence Induction of Anesthesia: A Probability-based Approach
Induction of anesthesia: After 3 minutes pre-oxygenation with 100% oxygen, a blinded dose alfentanil (0,10,20,30,40,50 or 60 µg/kg, followed by thiopental 4 mg/kg and rocuronium 0.6 mg/kg will be administered over 15 sec.
- Trial name
- NCT01518608
- Testing
- Alfentanil 0.5mg/ml (Rapifen , Janssen-Cilag)
- Where
- 2 sites in Norway
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Postoperative Pulmonary Complications
Postoperative Pulmonary Complications in Major Abdominal Surgery
Incidence of Postoperative Pulmonary Complications (PPCs) varies from 2% to 19%, according to the population under examination and the criteria used to define pulmonary complications. There is no univocal definition of PPCs.
- Trial name
- NCT01701908
- Where
- 40 sites in Italy
- Volunteers
- 1,542 people
- Sponsor
- University of Udine
Intubation; Difficult or Failed, Intubation Complication
Real-time Sonography in Detecting Inadvertent Esophageal Intubation Among Difficult Intubation Patients
Early detection of esophageal intubation, one of the most common complications while performing endotracheal intubation (ETI), is crucial to adequate airway management, especially among patients suspected of difficult intubation…
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Ultrasonography, Diagnostic Imaging
- Trial name
- SDEIDI (NCT05036460)
- Testing
- Ultrasonography, Direct visualization
- Volunteers
- 278 people
- Sponsor
- Peking Union Medical College Hospital