Clinical trials: Intrauterine Diseases
Intrauterine Adhesion
Postoperative Intermittent Intrauterine Balloon Dilatation Therapy.
In this prospective, randomized, controlled study, the investigators wish to determine the efficacy of intrauterine balloon (IUB) dilatation in the prevention of adhesion reformation when compared with the conventional management.
- Trial name
- NCT03131596
- Testing
- IUB dilatation therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Epilepsy, Contraception
Women With Epilepsy: a Pilot Study of PK and PD Anti-epileptic Drug Effects in Levonorgestrel Intrauterine System Users
The investigators will conduct a prospective, seven-month pilot study to explore pharmacokinetic (PK) and pharmacodynamic (PD) effects among women with epilepsy using the levonorgestrel intrauterine system (LNG IUS) for…
- Trial name
- WESAIL (NCT02362373)
- Testing
- levonorgestrel IUS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Intrauterine Growth Restriction, Villitis
Predicting Placental Pathologies by Ultrasound Imaging
Intrauterine growth restriction (IUGR) is caused when the placenta cannot provide enough nutrients to allow normal growth of the fetus during pregnancy.
- Conditions
- Intrauterine Growth Restriction, Villitis, IUGR
- Trial name
- NCT04506970
- Testing
- Comprehensive Doppler Ultrasound of the Placenta, Verasonics Ultrasound scanner (ultra-sensitive Doppler imaging)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility
Effect of Cervical Occlusion During Intrauterine Insemination (IUI)
Study Hypothesis: There is a difference in pregnancy rates between intrauterine insemination (IUI) in cycles performed with cervical occlusion by a balloon catheter designed for sonohysterograms as compared to those performed…
- Trial name
- NCT00951171
- Testing
- Intrauterine Insemination, IUI with the standard inseminator
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Intrauterine Growth Retardation
Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery
Intrauterine growth retardation (IUGR) occurs in approximately 3 to 10% of singleton pregnancies, in 9.1% of all twins and 9.9% of monochorionic twins.
- Trial name
- NCT01177553
- Testing
- selective laser photocoagulation of communicating vessels, Expected Management
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Asherman's Syndrome
Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
The purpose of this study is to compare the outcome of loop intrauterine contraceptive device and heart-shaped intrauterine balloon for the adjunctive treatment of severe intrauterine adhesions in patients with infertility.
- Trial name
- ROABTIPWSIUA (NCT02708277)
- Testing
- loop-shaped intrauterine contraceptive device, intrauterine balloon (Cook Medical)
- Volunteers
- 93 people
- Sponsor
- Yuqing Chen
Uterine Perforation
European Active Surveillance Study for Intrauterine Devices
The primary objective of the study is to assess the risks of intrauterine device (IUD) use in a study population that is representative for the actual users of the individual IUDs.
- Trial name
- EURAS-IUD (NCT00461175)
- Where
- Germany
- Volunteers
- 63,194 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Intrauterine Adhesions
Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy
Seprafilm is an FDA-approved temporary bioresorbable barrier that physically separates opposing tissue surfaces. The physical presence of the membrane separates adhesiogenic tissue while the normal tissue repair process takes…
- Trial name
- Seprafilm (NCT01632202)
- Testing
- Seprafilm, Sterile Saline Solution
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
Tolerability and Satisfaction With Evie
The purpose of this study is to determine patient satisfaction and tolerability of the Evie® slow-release insemination device for US population.
- Trial name
- NCT01969812
- Testing
- Evie Slow-release Insemination Device, Traditional Intrauterine Insemination
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Infertility
Does Endometrial Injury Improve Intrauterine Insemination Outcome?
The investigator suggests that local endometrial injury using pipelle catheter performed in the follicular phase (cycle day 5, 6 or 7) of the stimulation cycle may improve the pregnancy rates among patients undergoing…
- Trial name
- NCT02542280
- Testing
- endometrial injury., intrauterine insemination, ovarian stimulation
- Volunteers
- 360 people
- Sponsor
- Ain Shams Maternity Hospital
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
HIV
Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women
This study will inform international medical guidelines as to whether the Levonorgestrel intrauterine device (LNG IUD), a highly effective long-acting reversible contraceptive method, is safe and acceptable as compared to the…
- Trial name
- NCT01721798
- Testing
- Mirena levonorgestrel IUD, Copper T-380a IUD
- Where
- South Africa
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- FHI 360