Clinical trials: Intraocular Pressure
Inflammation, Intraocular Pressure
Efficacy Comparison Study of Steroids to Control Post-operative Inflammation
Phacoemulsification is a quick method with less complication for cataract surgery. Due to the use of ultrasonic energy, it produced more post-operative inflammation than other methods.
- Trial name
- NCT01801774
- Testing
- Subtenon 20-mg triamcinolone injection
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Mahidol University
Sickle Cell Disease
Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease
This study will examine sleep disordered breathing and sleep quality in participants (ages 12-25) diagnosed with sickle cell disease of any genotype.
- Trial name
- NCT06477289
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- St. Jude Children's Research Hospital
Glaucoma, Ocular Hypertension
Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty
The purpose of the study is to compare the safety and efficacy of two drops used to lower eye pressure when given prior to a glaucoma laser procedure.
- Trial name
- NCT00567411
- Testing
- brimonidine 0.1%, Apraclonidine 0.5%
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Walter Reed Army Medical Center
Intraocular Pressure
The Effects of Intubation Via McGrath Videolaryngoscope on Intraocular Pressure
In this study, the investigators aimed to compare the effects of endotracheal intubation via direct laryngoscope (DLS) and McGrath Videolaryngoscope (VL) on intraocular pressure.
- Trial name
- NCT03003598
- Testing
- Videolaryngoscope, Direct laryngoscope
- Volunteers
- 50 people
- Sponsor
- Inonu University
Intraocular Pressure, Caffeine Dosage
The Effect of Dosage of Caffeine on Intraocular Pressure
The goal of the study is to determine the effect of different doses of caffeine on intraocular pressure. We hypothesized that higher dosage of caffeine would increase intraocular pressure more than lower doses.
- Trial name
- NCT01793311
- Testing
- decaffeinated coffee, regular dose coffee, high dose coffee
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Glaucoma
Glaucoma Laser Assessment of Stability and Sustainability
The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or…
- Trial name
- GLASS (NCT06963684)
- Testing
- Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Twin Cities Eye Consultants
Cataract, Intraocular Pressure
Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification
This study aims to evaluate the effect of fixed brinzolamide-brimonidine combination on intaocular pressure after uncomplicated phacoemulsification surgery.
- Trial name
- NCT03494257
- Testing
- Brinzolamide-Brimonidine fixed combination
- Where
- Greece
- Volunteers
- 62 people
- Sponsor
- University Hospital of Patras
Ocular Hypertension, Open Angle Glaucoma
Study of AR-13324 in Patients With Elevated Intraocular Pressure
In this double-masked, vehicle-controlled, dose-response study, subjects will be randomized to receive AR-13324 Ophthalmic Solution 0.01%, 0.02%, and 0.04% or its vehicle (one eye), once daily (QD)in the morning (AM) for 7 days.
- Trial name
- NCT01528787
- Testing
- AR-13324 Ophthalmic Solution 0.01%, AR-13324 Ophthalmic Solution 0.02%, AR-13324 Ophthalmic Solution 0.04%
- Where
- 11 sites in United States
- Volunteers
- 85 people
- Sponsor
- Aerie Pharmaceuticals
Glaucoma
Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome
The purpose of this study is to evaluate the adjunctive effect of intratenon Bevacizumab on the result of trabeculectomy in primary term of intraocular pressure (IOP).
- Trial name
- Bevacizumab (NCT01263834)
- Testing
- Bevacizumab, Mitomycin C
- Where
- Thailand
- Volunteers
- 39 people
- Sponsor
- Prince of Songkla University
Glaucoma
A Compassionate Case Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Glaucoma Patients With Uncontrolled Intraocular Pressure to Avoid Surgical Intervention
A. To evaluate the ocular hypotensive efficacy of the rho-kinase Inhibitor (AR-12286 0.5% and 0.7%) ophthalmic solutions in open-angle glaucoma patients with uncontrolled IOP who are facing surgical intervention.
- Trial name
- NCT02174991
- Testing
- Rho-Kinase Inhibitor (AR-12286)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Glaucoma Research Institute
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Glaucoma
Blood Flow of Ophthalmic Artery and Glaucoma
The main purpose of this project is to investigate the blood flow of the ophthalmic artery (OA) in patients with ocular hypertension, high tension glaucoma and normal tension glaucoma.
- Trial name
- NCT02656979
- Testing
- Latanoprost
- Where
- Sweden
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Umeå University
Open-Angle Glaucoma, Ocular Hypertension
The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG)
Both Cosopt® and Xalatan® plus Timoptic® will significantly lower IOP, however only Cosopt® will demonstrate positive hemodynamic effects.
- Trial name
- Xal-Cos (NCT00815373)
- Testing
- Dorzolamide+Timolol Maleate0.5%, Latanoprost+Timolol Maleate0.5%+Lytears
- Where
- Israel
- Sponsor
- Meir Medical Center
Intraocular Pressure Changes After Glucosamine Sulfate Consumption.
Effect of Glucosamine on Intraocular Pressure
In this double blind clinical trial 92 patients suffering from rheumatoid arthritis are included. Those with the history of intraocular and corneal surgery, diabetic and heavy smokers are excluded from the study.
- Trial name
- NCT02306083
- Testing
- glucosamine sulfate 1500 mg three times a day
- Where
- Iran
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Intraocular Pressure
the Impact of EECP on Intraocular Pressure
EECP therapy may affect the intraocular pressure while improving the ischemia systemic organ blood perfusion the same time. The present study investigated the impact of Enhanced Extracorporeal Counterpulsation treatment on the…
- Trial name
- NCT01774188
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Primary Open Angle Glaucoma, Ocular Hypertension
Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost
This is a pilot, proof of concept study to evaluate the safety and efficacy of ALZ-1101 dosed once daily for 28 days compared to latanoprost 0.005% ophthalmic solution in patients with elevated intraocular pressure not adequately…
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Elevated Intraocular Pressure
- Trial name
- NCT01896180
- Testing
- ALZ-1101, Latanoprost
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Alleanza Pharmaceuticals, Inc.
Glaucoma, Open Angle Glaucoma
Performance and Safety of the ARGOS-SC Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery
The purpose of this study is to evaluate both the safety and feasibility of the surgical implantation of the ARGOS-SC implant during non-penetrating glaucoma surgery and the safety and usability of the ARGOS-SC implant and system…
- Trial name
- ARGOS-SC01 (NCT03756662)
- Testing
- ARGOS-SC suprachoroidal pressure sensor
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Implandata Ophthalmic Products GmbH
End-Stage Renal Disease
Feasibility Study of Arterial Stiffness in Hemodialysis Patients
People with kidney failure have a higher chance of getting disease in the blood vessels and this result in a decreased elasticity of the arteries of their body which make them very stiff or hard.
- Trial name
- NCT02196610
- Testing
- Applanation tonometry
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Intraocular Pressure Changes During Tracheal Extubation
Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade
The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation.
- Trial name
- NCT02215382
- Testing
- sugammadex, neostigmine+atropine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ordu University