Clinical trials: Intraocular Pressure
Intraocular Pressure
Effect of Central Corneal Thickness On IOP Using Various Tonometers
The primary purpose of this study is to evaluate the effects of ocular physical properties on intraocular pressure (IOP) measurements in eyes with healthy corneas using the following instruments to measure IOP: Goldmann…
- Trial name
- CCT (NCT00570791)
- Testing
- Tonometer
- Where
- 2 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Laparoscopic Surgery, Intraocular Pressure
The Effect of the Steep Trendelenburg Position on Intraocular Pressure
A total of 50 patients aged between 18-60 years, classified as American Society of Anesthesiologists (ASA) I-II, undergoing elective total laparoscopic hysterectomy in the steep trendelenburg position (STP) will be included in…
- Trial name
- NCT06440642
- Testing
- tonopen
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Intraocular Pressure, Anesthesia
Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
The aim of the study to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia on intraocular pressure (IOP) during coronary artery bypass graft surgery (CABG) with cardiopulmonary…
- Trial name
- NCT06494969
- Testing
- Intraocular pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Antalya Training and Research Hospital
Glaucoma, Acupuncture
Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial
This clinical trial used acupuncture as an adjunctive treatment for glaucoma patients. A randomized, controlled trial involving 50 subjects will be conducted and observed for 12 weeks to evaluate the clinical efficacy of…
- Conditions
- Glaucoma, Acupuncture, Intraocular Pressure
- Trial name
- NCT05753137
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- China Medical University Hospital
Intraocular Pressure
Self-monitoring of the Intraocular Pressure Versus Hospital-based Diurnal Monitoring
Glaucoma remains the leading cause of irreversible blindness worldwide. Glaucoma represents a group of diseases that lead to optic nerve damage and corresponding deterioration of the visual field.
- Trial name
- NCT04485897
- Testing
- icare HOME device (Icare Oy, Vanda, Finland)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Intraocular Pressure
The Effect of Brimonidine
This study will evaluate whether pre-treating patients with Brimonidine 0.2% before and/or after dilating the pupils will help to control the changes in intraocular pressure often seen when using dilating drops.
- Trial name
- NCT03959176
- Testing
- Brimonidine, Tropicamide, Phenylephrine Ophthalmic Product
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Glaucoma, Intraocular Pressure
Self Tonometry and Transfer of Glaucoma Patients' Data for Improving the Supply Situation
The SALUS project is developing a new form of care, the application of self-tonometry by the patient itself, and an accompanying electronic case file connecting clinics, doctor's offices and patients.
- Conditions
- Glaucoma, Intraocular Pressure, Patient Empowerment, Telemedicine
- Trial name
- SALUS (NCT04698876)
- Testing
- Self-tonometry by means of ICareHOME, Intraocular measurement by means of rebound tonometry or Goldmann applanation tonometry, Blood pressure
- Where
- 5 sites in Germany
- Volunteers
- 267 people
- Sponsor
- University Hospital Muenster
Intraocular Pressure
Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG)
To evaluate the IOP (Intraocular Pressure) lowering efficacy and safety of Brinzolamide 1.0% (Azopt), dosed twice daily as adjunctive therapy in patients treated with Travoprost 0.004% (Travatan) once daily.
- Trial name
- NCT00758342
- Testing
- Travoprost 0.004% + Brinzolamide 1.0%, Travoprost 0.004% + Tears Natural
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Intraocular Pressure
iCare ST500 Clinical Trial
Clinical validation of iCare ST500 tonometer per ANSI Z80.10:2014 standard
- Trial name
- NCT05742009
- Testing
- iCare ST500, GAT, iCare IC200
- Where
- Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure
Aqueous Humor Dynamics and Brimonidine
This single-center, investigator-masked, crossover study is designed to investigate the circadian rhythms of aqueous humor dynamics in human subjects with ocular hypertension (OHT) before and after intervention with a commonly…
- Trial name
- Brimonidine (NCT01144494)
- Testing
- Brimonidine, Artificial tears
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Nebraska
Intraocular Pressure and PROSE Lens
Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study
The goal of this research is to determine the reproducibility of measurements of intraocular pressure (IOP) when a scleral lens is on the eye.
- Trial name
- NCT04308941
- Testing
- Intraocular pressure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Intraocular Pressure
Effects of Intubation on Intra-ocular Pressure and Optic Nerve Sheath Diameter
Brief Summary: In this study, the investigators aimed to compare the effects of different types of endotracheal instruments (Machintosh laryngoscope, McGrath videoingoscope and C-Mac videoryngoscope) on intraocular pressure…
- Trial name
- [Intubation] (NCT05763056)
- Testing
- McGrath videolaryngoscopy, C-MAC videolaryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anesthesia, Disk Herniated Lumbar
Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery
The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.
- Conditions
- Anesthesia, Disk Herniated Lumbar, Intraocular Pressure
- Trial name
- NCT06070480
- Testing
- Spinal Anesthesia Group, Desflurane Group, Propofol Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Elevated Intraocular Pressure (IOP)
Safety and Intraocular Lowering Effect of Delivery of Travoprost Evolute® in Subjects With Elevated Intraocular Pressure
This is a pilot, open-label, multi-center clinical study. Each potential subject that has met all screening inclusion/exclusion criteria will undergo a six-week washout phase where they will discontinue the use of their topical…
- Trial name
- NCT04962009
- Testing
- Travoprost Evolute® (Travoprost Punctal Plug Delivery System), 166 ug
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mati Therapeutics Inc.
Intraocular Pressure
IOP Elevation Study
The purpose of this study is to improve understanding of the pathophysiologic process that leads to the development of glaucamotous damage.
- Trial name
- NCT03400137
- Testing
- Increasing of intraocular pressure (IC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Corneal Edema, Corneal Defect
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery
Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg insert following corneal transplant surgery (PKP, DSEK, DMEK) as compared to topical prednisolone acetate 1%.
- Conditions
- Corneal Edema, Corneal Defect, Corneal Transplant, Penetrating KeratoPlasty
- Trial name
- NCT04521140
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Nicole Fram M.D.
Intraocular Pressure
Comparative Study of the NIDEK TONOREF III and the Haag-Streit Goldmann Manual Tonometer and Comparison of Pachymetry Values for NIDEK TONOREF III With the NIDEK CEM-530
The primary objective of this clinical study is to prove that tonometry values for NIDEK TONOREF III are comparable to the predicate device and to prove that the pachymeter function of NIDEK TONOREF III is equivalent to the…
- Trial name
- NCT03441477
- Testing
- Nidek Tonoref III, Haag-Streit Goldmann Manual Tonometer, NIDEK CEM-530
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Cataract, Intraocular Pressure
High Intraocular Pressure After Cataract Surgery
Effectiveness of anterior chamber drainage on the structure of the anterior chamber, the position of the intraocular lens and the shape of the corneal incision in the early stage of cataract surgery with high intraocular pressure
- Trial name
- NCT05834465
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Intraocular Pressure, Open Angle Glaucoma
A FIH Trial of the STREAMLINE™ SURGICAL SYSTEM
The purpose of this study is to evaluate the safety and Intraocular pressure lowering effectiveness of the Streamline™ Surgical System.
- Trial name
- NCT04700189
- Testing
- ab interno canaloplasty
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- New World Medical, Inc.
Primary Open Angle Glaucoma, Intraocular Pressure
Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Frequency Deep Sclerotomy
Highlights the high-frequency deep sclerotomy (HFDS) as a promising ab-interno surgery in primary open-angle glaucoma (POAG) patients and evaluates the efficacy and safety of the procedure.
- Conditions
- Primary Open Angle Glaucoma, Intraocular Pressure, Glaucoma Surgery
- Trial name
- HFDS (NCT05466526)
- Testing
- High frequency deep sclerotomy (HFDS)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch