Clinical trials: Intracranial Pressure Increase
Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP)
Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure
The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow.
- Conditions
- Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP), Laparoscopy, Cerebral Perfusion and Oxygenation
- Trial name
- NCT03640741
- Testing
- Laparoscopy
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences
Coma
Optic Nerve Sheath Diameter as a Screening Test for Increased Intracranial Pressure
Patients admitted to the ICU may have delayed awakening after their critical illness has resolved. Though most either are due to metabolic causes or delayed elimination of sedative medications, more serious pathologies such as…
- Trial name
- NCT02338284
- Testing
- ultrasound of globe
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Intracranial Hypertension
Comparison of the Effects of Deep and Moderate Neuromuscular Blockade on Optic Nerve Sheath Diameter
Increased intracranial pressure (IICP) is a common problem in traumatic brain injuries and many medical diseases. Early recognition of IICP can save lives.
- Trial name
- MBLONDE (NCT04211064)
- Testing
- Ultrasonographic measurement of optic nerve sheath diameter, Deep neuromuscular block, Moderate neuromuscular block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Brain Injuries, Intracranial Pressure Increase
Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Patients
The purpose of this clinical research project is to employ Mespere LifeSciences NeurOs Cerebral Oximetry system, equipped with noninvasive sensors approved by the FDA, to monitor and investigate the correlation within a cohort of…
- Conditions
- Brain Injuries, Intracranial Pressure Increase, Monitoring
- Trial name
- Mespere ICP (NCT06511804)
- Testing
- Intracranial Pressure Noninvasive Monitoring
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Louisville
Acute Brain Injuries
Effect of Increased Positive End-expiratory Pressure on Intracranial Pressure in Different Respiratory Mechanic in Acute Respiratory Distress Syndrome
There are concerns that the use of positive end-expiratory pressure (PEEP) for the treatment of pulmonary complications in patients with brain injury may potentially elevate intracranial pressure (ICP), and deteriorate…
- Trial name
- NCT02670733
- Testing
- Positive end-expiratory pressure
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Traumatic Brain Injury
Diagnosis of Intracranial Hypertension Using TCCD, ONSD and ODH by Bedside Ultrasound
The goal of this observational study is to investigate several means of measuring intracranial pressure (ICP) non-invasively in patients who had head trauma and received implantation of invasive ICP monitor device.
- Trial name
- NCT07151287
- Testing
- TCCD, ONSD, ODH
- Volunteers
- 64 people
- Sponsor
- Xiangya Hospital of Central South University
Intracranial Pressure Increase
Evaluation of the Effect of Trendelenburg Position Duration on Intracranial Pressure
The Lloyd Davies position is a position used in laparoscopic hysterectomies where the head is lowered 45 degrees and the legs are bent from the knee area.It is a version of the Trendelenburg position.
- Trial name
- NCT06048900
- Testing
- ultrasound guided optic nerve sheath diameter measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Dilek Cetinkaya
Intracranial Hypertension
Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age
An increase of intracranial pressure (ICP) is an important cause of secondary brain damage. The gold standard for measuring ICP is represented by invasive positioning of intracranial ICP devices.
- Trial name
- nICPped (NCT05340062)
- Testing
- bedside sonography
- Where
- 6 sites in Italy
- Volunteers
- 46 people
- Sponsor
- Azienda Ospedaliera di Padova
Intraocular Pressure, Intracranial Pressure Increase
Correlation Intraocular Pressure With Intracranial Pressure
Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis.
- Conditions
- Intraocular Pressure, Intracranial Pressure Increase, Trauma, Brain, Children, Only
- Trial name
- IOPICPTBI (NCT03344432)
- Testing
- with intraocular pressure high, without intraocular pressure high
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital Civil de Guadalajara
Trauma, Brain, Subarachnoid Hemorrhage
Non-invasive ONSD-based Neuromonitoring in a Neurointensive Care Setting
Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD).
- Conditions
- Trauma, Brain, Subarachnoid Hemorrhage, Intracranial Hypertension
- Trial name
- ONSDDynamics (NCT05818371)
- Testing
- Sonographic determination of the optic nerve sheath diameter
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Intracranial Hypertension
A Novel Non-invasive Technique of Cerebral Compliance and Auto-regulation Assessment
Introduction: Intracranial pressure (ICP) monitoring is essential in several medical situations, however, currently there is an invasive technique, costly, not widely available and sometimes contraindicated.
- Trial name
- NCT03144219
- Testing
- Transcranial Doppler (TCD) ultrasound monitoring, Non invasive intracranial compliance monitoring
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- University of Sao Paulo
Idiopathic Intracranial Hypertension, Intracranial Pressure
The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure
50 patients with verified new-onset Idiopathic Intracranial Hypertension are randomly allocated to standard weight management (dietician counselling) or trial intervention consisting of subcutaneous injections with Semaglutide…
- Conditions
- Idiopathic Intracranial Hypertension, Intracranial Pressure, Obesity, Pseudotumor Cerebri Syndrome
- Trial name
- IIH:DUAL (NCT06027567)
- Testing
- Semaglutide, Very Low Calorie Diet, Dietician counselling
- Where
- 2 sites in Denmark
- Volunteers
- 38 people
- Sponsor
- Rigmor Højland Jensen
Optic Nerve Sheath Diameter, Intracranial Pressure Increase
Intraoperative Optic Nerve Sheath Diameter Changes After Laparoscopic Surgery
Laparoscopic surgery is a widely used alternative to open surgery; Advantages include reduced bleeding and pain intensity, shorter hospital stay, and improved cosmetic results.
- Trial name
- NCT06209034
- Testing
- Optic nerve sheath measurement
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Kocaeli University
Subarachnoid Hemorrhage (SAH)
ICP Versus Intracranial Compliance Guided Management in SAH
The purpose of this study is to determine whether treatment guided also by ICP mean wave amplitude improves outcome compared to international standard care in patients with SAH.
- Trial name
- NCT00248690
- Testing
- ICP mean wave amplitude
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Intracranial Hypertension
Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure
The purpose of this study is to determine whether mannitol is as effective as hypertonic saline solution in the treatment of elevated intracranial pressure in patients with brain injury.
- Trial name
- NCT00447018
- Testing
- 20% mannitol, 7.45% hypertonic saline solution
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Optic Disc Swelling
Antiacne Medications Pseudotumor Cerebri
The exact incidence of optic disc swelling and idiopathic intracranial hypertension in patients using antiacne medication is not known so far.
- Trial name
- AAMPTC (NCT02149615)
- Testing
- Retinal nerve fibre layer measurement
- Where
- Switzerland
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Zurich
End- Stage Renal Disease Patients
The Hemodynamic Effects During Sustained Low-efficiency Dialysis Versus Continuous Veno-venous Hemofiltration for Patients With Intracranial Hypertension in a Cross Over Study
Hemodynamic instability occurs frequently during dialysis treatment and still remains as significant cause of patient mobility and mortality.
- Trial name
- NSARF (NCT01781585)
- Testing
- hemodialysis
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Intracranial Pressure Increase, Mechanical Ventilation Complication
Lung Recruitment and PEEP Effects on Intracranial Pressure in Cranial Surgery
High positive end-expiratory pressure (PEEP) levels required to achieve clinical benefits may increase ICP and reduce cerebral perfusion pressure (CPP) in patients at risk of intracranial hypertension.
- Trial name
- NCT06771232
- Testing
- Subdural pressure measurement
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Intracranial Pressure Increase
Effect of Acetazolamide on Optic Nerve Sheath Diameter in Laparoscopic Donor Nephrectomies
The purpose of the trial is to study the effect of acetazolamide administered via Ryle's tube on optic nerve sheath diameter in laparoscopic live donor nephrectomy patients.
- Trial name
- NCT03005665
- Testing
- Acetazolamide, Normal Saline
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Posterior Reversible Encephalopathy Syndrome
Posterior Reversible Encephalopathy Syndrome in the Critically Ill Patients
Posterior Reversible Encephalopathy Syndrome prospective (PRES) registry. Data collection using a standardized form : demographic data and data related to the PRES, including circumstances of onset, dates and times of onset and…
- Trial name
- NCT03470467
- Testing
- No intervention
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ictal Group