Clinical trials: Intracerebral Hemorrhage, open to volunteers
Severe Traumatic Brain Injury, Severe Brain Injury
The Örebro Severe Traumatic Brain Injury Registry
Traumatic brain injury and other severe brain injuries requiring neurointensive care are associated with high mortality, long-term disability and substantial societal burden.
- Conditions
- Severe Traumatic Brain Injury, Severe Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- ÖrSBID (NCT07398274)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- András Zoltán Buki
Nervous System Diseases, Cerebrovascular Disorders
Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage
MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard…
- Conditions
- Nervous System Diseases, Cerebrovascular Disorders, Cardiovascular Diseases, Vascular Diseases
- Trial name
- MSU-ICH (NCT07665827)
- Testing
- Mobile Stroke Unit Management, Standard Management
- Where
- China
- Volunteers
- 706 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracerebral Hemorrhage
Vitamin D for Acute Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is the most deadly and debilitating form of stroke. To date, effective treatment that could improve the functional outcome of ICH remained elusive.
- Trial name
- VICToHR (NCT07458815)
- Testing
- Vitamin D
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Basal Ganglia Hemorrhage, Intraventricular Hemorrhage
RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH
Intracerebral hemorrhage (ICH) is one of the most devastating forms of stroke, with high rates of death and disability worldwide. Despite advances in medical and surgical care, effective therapeutic options remain limited.
- Conditions
- Basal Ganglia Hemorrhage, Intraventricular Hemorrhage, Brainstem Stroke, Intracranial Hemorrhage, Spontaneous
- Trial name
- RAINBOW-ICH (NCT07205263)
- Testing
- AI-assisted robotic-guided endoscopic hematoma evacuation, Conventional craniotomy, AI-assisted robotic-guided puncture and hematoma evacuation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Intracerebral Haemorrhage
The Planetary Outcomes After Intracranial Haemorrhage Study
Over twelve million strokes occur worldwide every year, and stroke is the second most common cause of death globally. Strokes happen because blood supply to the brain is damaged.
- Conditions
- Stroke, Intracerebral Haemorrhage, Subarachnoid Haemorrhage (SAH)
- Trial name
- PLOT-ICH (NCT06731751)
- Testing
- Management of spontaneous intracranial haemorrhage
- Volunteers
- 1,000 people
- Sponsor
- University of Cambridge
Intracerebral Hemorrhage, Cerebral Hemorrhage
High Risk of Death or Disability in Brain Hemorrhage: Role of Spot Sign and Secondary Markers
This study looks at patients with brain hemorrhage to see if a special sign on brain scans, called the "Spot Sign," combined with other scan features, can predict a higher risk of death or disability.
- Conditions
- Intracerebral Hemorrhage, Cerebral Hemorrhage, Stroke, Brain Injuries
- Trial name
- NCT07172542
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier de Gonesse
Spontaneous Intracranial Hemorrhage, Hypertension
Tranexamic Acid with Intensive Blood Pressure Management in Ultra-Early Intracerebral Hemorrhage
This is a prospective, multicenter, randomized, quadruple-blind, placebo-controlled study. This study aims to estimate the safety and efficacy of intravenous tranexamic acid (TXA) combined with intensive blood pressure lowering…
- Trial name
- TIME-ICH (NCT06760078)
- Testing
- intravenous tranexamic acid (TXA) infusion
- Where
- 2 sites in China
- Volunteers
- 532 people
- Sponsor
- Xuanwu Hospital, Beijing
Traumatic Brain Injury (TBI), Intracerebral Hemorrhage
Hemodynamic ABI Monitor
The goal of this observational study is to explore the relationship of heart function with the course and outcomes after traumatic brain injuries and nontraumatic intracerebral hemorrhage.
- Trial name
- NCT06725108
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Intracerebral Hemorrhage, Hypertension
MOBILE Health Intervention in IntraCerebral Hemorrhage Survivors
This randomized controlled trial investigates the efficacy and safety of mobile health intervention in managing hypertension after Intracerebral Hemorrhage (ICH).
- Trial name
- MOBILE-ICH (NCT05830305)
- Testing
- Mobile health intervention
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The University of Hong Kong
Intracranial Hemorrhage, Hypertensive
Yiqi Huayu Jiedu Therapy for Non-Surgical Supratentorial Hypertensive Intracerebral Hemorrhage
This multicenter, prospective, double-blind, randomized controlled trial will enroll 902 non-surgical patients with supratentorial hypertensive intracerebral hemorrhage who meet the traditional Chinese medicine syndrome criteria…
- Trial name
- CHAIN2 (NCT07580235)
- Testing
- Yiqi Huayu Jiedu Mixture Intervention
- Volunteers
- 902 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Stroke, Intracerebral Haemorrhage
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
The goal of this study is to test if Savvy, a multimodal intervention (consisting of psychological exercises, a weekly pill organizer, and a text message reminder system) can improve medication adherence in stroke survivors.
- Conditions
- Stroke, Intracerebral Haemorrhage, Ischemic Stroke, TIA (Transient Ischemic Attack)
- Trial name
- NCT07414732
- Testing
- Savvy Medication Adherence Intervention
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Insulin-Like Growth Factor I
Study on Dynamic Changes of Serum IGF-1 Post-Cerebral Hemorrhage and Its Prognostic Correlation
The purpose of this study is to dynamically observe the dynamic changes of serum IGF-1 after intracerebral hemorrhage, explore the impact and correlation of serum IGF-1 with the severity of the patient's condition and prognosis…
- Trial name
- NCT07043504
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Intra Cerebral Hemorrhage
Maximal Medical Treatment of Intracerebral Haemorrhage Pilot Trial - MAX-ICH Pilot Trial
The MAX-ICH pilot trial is a phase-II study aimed at assessing the feasibility and safety of a comprehensive care bundle for patients with intracerebral hemorrhage (ICH).
- Trial name
- MAX-ICH (NCT06648369)
- Testing
- MAX-ICH care bundle, Standard of care
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kangaroo Care, Premature Infant
Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care
This clinical study aims to find out whether kangaroo care (skin-to-skin contact between parents and their extremely premature newborns) can help protect the babies' brains by reducing the risk of bleeding in the brain during the…
- Conditions
- Kangaroo Care, Premature Infant, IVH- Intraventricular Hemorrhage
- Trial name
- KANVIH (NCT07473882)
- Testing
- Lateral, Prone, Incubator care
- Where
- Spain
- Volunteers
- 314 people
- Sponsor
- Hospital Universitario 12 de Octubre
OCTA, Severe Brain Injury
Effect of the Stellate Ganglion Block on the Retinal Microcirculation
Surges in the sympathetic nervous system occur at the ictus of a variety of neurological critical illnesses including intracranial hemorrhage and ischemic stroke.
- Conditions
- OCTA, Severe Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT06797752
- Testing
- OCTA Scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures
Dutch Intracerebral Hemorrhage Surgery Trial
Background: Intracerebral hemorrhage (ICH) accounts for 16-19% of all strokes in Western Europe and contributes profoundly to mortality and disability.
- Conditions
- Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures, Endoscopic Surgical Procedures
- Trial name
- DIST (NCT05460793)
- Testing
- Minimally invasive endoscopy-guided surgery
- Where
- 11 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Stroke
Biomarkers Based EArly Diagnosis of STroke Subtype Cohort（Bio-EAST）
Intracerebral hemorrhage carries high rates of mortality and disability, imposes a significant societal burden. Based on findings from our previous multicenter randomized controlled clinical trial (INTERACT4), we revealed that…
- Trial name
- Bio-EAST (NCT07003477)
- Testing
- Detection of peripheral blood biomarkers
- Where
- China
- Volunteers
- 527 people
- Sponsor
- Shanghai East Hospital
Intracerebral Hemorrhage
Evaluating a Prototype CT Scan for ICH Evacuation
The aim of the project is to collect pre-procedural CT scans, intra-procedural post-evacuation scans as well as immediate post-procedural CT scans to evaluate and collect feedback of two Siemens prototypes: 1) perfusion prototype…
- Trial name
- ICH-CTP II (NCT07455201)
- Testing
- DynaCT Multiphase, DynaCT Sine Spin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Subarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage
The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Cortical spreading depolarisations are pathological depolarisation waves that occur frequently after severe acute brain injury and has been associated with poor outcome.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage, Traumatic Brain Injury
- Trial name
- KETA-BID (NCT05095857)
- Testing
- S-ketamine
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intracerebral Haemorrhage, Paediatric Stroke
Master Study Protocol for the Cohort of the Specialist Network Stroke (SN Stroke)(Stroke-CORE)
The Stroke-CORE cohort aims to provide a comprehensive and up-to-date understanding of stroke care in Germany. To achieve this, patients are followed along the entire continuum of care-from initial management before hospital…
- Conditions
- Intracerebral Haemorrhage, Paediatric Stroke, Stroke Acute, Stroke
- Trial name
- Stroke-CORE (NCT07553650)
- Where
- 12 sites in Germany
- Volunteers
- 12,750 people
- Sponsor
- Charite University, Berlin, Germany