Clinical trials: Intraarticular Injection
Pain, Satisfaction, Patient
Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis
The evolving reports form recent studies are creating a promise on the potential use of dextrose injections for treating arthritis and replacing current method of treating early osteoarthritis by corticosteroids by giving long…
- Conditions
- Pain, Satisfaction, Patient, Functionality
- Trial name
- NCT04791202
- Testing
- Dextrose, Methylprednisolone Acetate 40 MG/ML
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Knee Osteoarthritis
Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis
Knee osteoarthritis (OA) is characterized by loss of cartilage leading to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03788265
- Testing
- Lipogems
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intra-articular Injections
Use of BIP-Needles in Rheumatologic Injections
The study focuses on needle guidance in rheumatologic operations - glucocorticoid injections inside joint capsules specifically.
- Trial name
- NCT02605928
- Testing
- Injeq Bioimpedance Probe (BIP) Needle
- Where
- Finland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Injeq Ltd
Drug-Drug Interaction
Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers
This study will be an open-label, parallel-arm study to determine if a prior intra-articular (IA) injection of lorecivivint (LOR) affects the safety, tolerability, and/or pharmacokinetics (PK) of a subsequent IA injection of the…
- Trial name
- NCT04598542
- Testing
- Lorecivivint (LOR), Triamcinolone acetonide (TA)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biosplice Therapeutics, Inc.
Anxiety Related to Pain Related to an Intraarticular Injection, Pain Related to an Intraarticular Injection
Aromatherapy and Anxiety Study
While intra-articular injections can alleviate pain in orthopedic patients, this can be an anxiety-provoking experience. Adult patients scheduled to receive an injection at the study location will be randomly assigned to one of…
- Trial name
- NCT05832983
- Testing
- Guided Meditation, Aromatherapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee
A Single Intra-articular Injection of aMAT vs PRP in Patients With OA of the Knee
The study proposes to compare performances and safety of intra-articular injections of aMAT with those of a control group (PRP injections) for the treatment of symptomatic OA of the knee.
- Trial name
- LIPOJOINT (NCT03117608)
- Testing
- injection of autologous micro-fragmented adipose tissue (aMAT), injection of Platelet-rich Plasma (PRP)
- Where
- Italy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Lipogems International spa
Osteoarthritis of the Knee
The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator
Osteoarthritis is the most common disease effecting human beings with incidence of about 20% and prevalence close to 80% of the adult population.
- Trial name
- NCT00422643
- Testing
- Sodium hyaluronate (hyaluronic acid)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Chondromalacia, Osteoarthritis
Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection
The primary objective of this study is to confirm the superiority of intra-articular collagen injection in patients with knee joint pain compared to the control group.
- Conditions
- Chondromalacia, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539095
- Testing
- CartiZol, Normal saline
- Where
- 5 sites in South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Osteoarthritis, Accuracy of Intraarticular Needle Placement
Evaluation of the Medial Parapatellar Knee Injection Technique
The goal of our study is to present important anatomic considerations which should be considered before knee injection is performed.
- Trial name
- NCT00712972
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Adhesive Capsulitis
Comparison of Rotator Interval Injection Versus Intraarticular Hydrodilatation in Frozen Shoulder
This study was conducted to compare the efficacy of hydrodilatation with steroid via posterior approach versus rotator interval approach for treating patients with adhesive capsulitis.
- Trial name
- NCT03678038
- Testing
- Triamcinolone (Shincort) injection to rotator interval, Triamcinolone (Shincort) injection to posterior glenuhumeral recess
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Osteo Arthritis of the Knee, Pain
The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections
Osteoarthritis (OA) is the most common condition in middle-aged and elderly populations; it causes pain and physical disability and is characterized by cartilage degeneration, changes in bone tissue, inflammation of the synovial…
- Conditions
- Osteo Arthritis of the Knee, Pain, Pain Management, Exercise
- Trial name
- NCT07496203
- Testing
- BETY
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dextrose Concentration
Dextrose Concentration Decline Rate in Vivo
Measuring the speed of decrease in dextrose concentration to help design more accurate in vitro studies
- Trial name
- NCT06128122
- Testing
- Intrarticular and subcutaneous dextrose injection with timed measurement of dextrose levels
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Dr. Dean Reeves Clinic
Anterior Cruciate Ligament Reconstruction, Tranexamic Acid
Tranexamic Acid Injection With Different Drainage Clamping Time After Anterior Cruciate Ligament Reconstruction
Post-anterior cruciate ligament reconstruction (ACLR) hemarthrosis may result in increased pain thus delaying postoperative rehabilitation, which may eventually lead to arthrofibrosis and a functional deficit.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Tranexamic Acid, Hemarthrosis, Knee
- Trial name
- NCT06280456
- Testing
- Tranexamic Acid Powder
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
TMJ Disc Disorder
a Comparison of the Outcomes Following Intra-articular Dextrose 5% Injection Versus Arthrocentesis in Patients With Anterior Disc Displacement With Reduction of the Tomporomandibular Joint
The Aim of this study is to evaluate the efficacy of intra-articular Dextrose injection with concentration 5% in superior joint space of TMJ in comparison to arthrocentesis in patients with anterior disc displacement with…
- Trial name
- NCT07129681
- Testing
- dextrose 5%, Arthrocentesis/Saline
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis
Comparison Between Four Types of Single Dose Hyaluronic Acid Injection in Patients With Knee Osteoarthritis
Study design: Allocation: Randomized. Endpoint Classification: Comparative Study. Intervention model: Parallel Assignment. Masking: Double Blind (Subject, Assessed) Primary purpose: Comparison.
- Trial name
- NCT01998308
- Testing
- Crespine gel, Intragel, Crespine plus gel
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- October 6 University
Osteoarthritis, Knee
A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of LG00034053 in Patients With Knee OA
This study is a multi-center, randomized, placebo-controlled, double-blind clinical study, consisting of Part 1 (Phase 1b) in a sequential, dose-escalating design and Part 2 (Phase 2) in a parallel design.
- Trial name
- NCT05237752
- Testing
- LG00034053
- Where
- 2 sites in Australia, South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- LG Chem
Disc Disorder
Effect of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction
This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis…
- Trial name
- NCT05640206
- Testing
- i-PRF, Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ege University
Thumb Carpometacarpal Joint Osteoarthritis
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint.
- Trial name
- NCT00685880
- Testing
- Prolotherapy (10% dextrose solution), Betamethasone
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Knee Osteoarthritis
Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
Knee osteoarthritis (OA) causes patients considerable joint pain and leads to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03379168
- Testing
- Microfragmented Adipose Tissue (Lipogems), Corticosteroid injection, Saline
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dustin L. Richter, MD