Clinical trials: Intestinal Health
IBS - Irritable Bowel Syndrome
Study to Evaluate the Efficacy of Poppi Apple Cider Vinegar Prebiotic Soda to Improve Gut Health In Participants
This exploratory observational trial provides the opportunity to gather information on the effect of daily consumption of Poppi Apple Cider Vinegar Prebiotic Soda on gut health and digestion.
- Trial name
- NCT05418439
- Testing
- Drink Poppi Soda
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Drink Poppi
Colorectal Polyp, Inflammation
Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy.
- Conditions
- Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota
- Trial name
- NCT06603519
- Testing
- Modified Plant-Based Mediterranean Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women.
- Conditions
- T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
- Trial name
- NCT07222111
- Testing
- Dried plums
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dietary Behaviors, Sustainable Diets
Community-Based Nutritional Intervention Based on the Planetary Health Diet and Its Impact on Gut Microbiota in Rural Women in Mexico
This study aims to evaluate the impact of a community-based nutritional intervention based on the Planetary Health Diet on dietary patterns, gut microbiota composition, and health indicators in adult women living in rural…
- Conditions
- Dietary Behaviors, Sustainable Diets, Gut Microbiota, Nutrition Intervention
- Trial name
- PHD-RURAL (NCT07597811)
- Testing
- Community-Based Planetary Health Diet Intervention
- Where
- Mexico
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Edgar Leon
Colorectal Cancer, Colorectal Neoplasms
Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates
Behavioral economics principles have increasingly been shown to improve health outcomes in the United States. They offer the ability to implement simple, low-cost and effective interventions to address key health issues without…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
- Trial name
- NCT05115916
- Testing
- MyChart Priming Message
- Where
- United States
- Volunteers
- 3,880 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gut Microbiome
Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health
The objective of the proposed research is to determine the effects of fresh mango consumption on gut microbiome, and its relationship with skin health, sexual and mental health in relatively healthy adults.
- Trial name
- NCT06800833
- Testing
- Low fat cookies, Mango
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Blood Pressure, Body Composition, Immune Function
Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial
Accordingly, the purpose of this study is to evaluate the efficacy of 1) supplementation with Synbiotic (Plexus® Triplex), 2) commercially-available Probiotic, or 3) placebo control over 30 days on the gut microbiome…
- Trial name
- GUTRCT (NCT06544915)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Anorexia Nervosa
Active Lifestyle Intervention in Anorexia Nervosa: a Comprehensive Study
The goal of this study is to perform a comprehensive analysis of varied health markers and analyze the impact of lifestyle interventions on the prognosis of anorexia nervosa (AN) patients.
- Trial name
- DiANa (NCT06866301)
- Testing
- Progressive Resistance Exercise
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Healthy Infants
Efficacy of Two HMOs in Chinese Infants
This is a randomized, controlled, double-blind, intervention trial of healthy male and female term infants to evaluate the efficacy of the 2 HMOs on beneficially modulating the gut microbiota, gut maturation, gut barrier…
- Trial name
- NCT06361719
- Testing
- Experimental Group (EG), Control Group (CG)
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Gut Microbiome, Cholesterol, LDL
Corn and Heart Health Study
The purpose of this study is to investigate the effects of 3 different corn flours: (1) whole grain corn flour, (2) 50% refined corn flour + 50% corn bran derived from whole corn meal, and (3) refined corn flour, on…
- Conditions
- Gut Microbiome, Cholesterol, LDL, Cholesterol, HDL
- Trial name
- CHS (NCT03967990)
- Testing
- Refined cornmeal flour, 50/50 refined cornmeal-bran mix, Whole grain cornmeal flour
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Healthy Subjects (HS)
To Evaluate the Effect of Bacillus Coagulans Based Product in Gut Health and Immunomodulatory Effect in Healthy Adults
This randomized, double-blind, placebo-controlled clinical trial is designed to evaluate the effects of a Bacillus coagulans-based probiotic product on gut health, immunological parameters, and overall tolerability in healthy…
- Trial name
- NCT07377994
- Testing
- Probiotic (Bacillus Coagulans)
- Where
- India
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bioagile Therapeutics Pvt. Ltd.
Smoking Cessation, Weight Gain
Gut Microbiome and Weight Gain After Smoking Cessation
Investigating the effect of smoking and smoking cessation on the intestinal microbial composition and function. The investigators wish to determine whether the alteration in gut microbiome drives the significant weight gain seen…
- Trial name
- NCT04618705
- Testing
- Smoking Cessation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eran Elinav
Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers
This clinical trial evaluates how propionate and butyrate supplementation alters intestinal health in healthy volunteers and whether it would be feasible to administer these supplements to patients undergoing allogeneic…
- Conditions
- Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT07611370
- Testing
- Biospecimen Collection, Microencapsulated Sodium Butyrate, Microencapsulated Sodium Propionate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Bowel Preparation, Patient Experience
Impact of a Colonoscopy Preparation Mobile App on Colonoscopic Cleanliness and Experience
The most crucial factor determining the success and quality of a colonoscopy procedure is the patient's adherence to proper bowel preparation.
- Conditions
- Bowel Preparation, Patient Experience, Patient Satisfaction
- Trial name
- NCT06569277
- Testing
- A mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Colorectal Cancer (Diagnosis)
The Effectiveness of the mHealth Survivorship Program on Enhancing Health-related Quality of Life Among Colorectal Cancer Survivors
The goal of this clinical trial is to evaluate the effectiveness of the mHealth survivorship program in enhancing health-related quality of life among colorectal cancer survivors.
- Trial name
- NCT07158671
- Testing
- Intervention Group
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- The Nethersole School of Nursing
Healthy
Effects of Ethanol on Intestinal Permeability and Integrity
Alcohol consumption is a major health problem worldwide. It affects all systems of the body especially the gastrointestinal tract.
- Trial name
- NCT00928733
- Testing
- Gastroduodenoscopy- Intraduodenal intubation
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Yogurt Intake, Gastrointestinal Immune Function
Yogurt and GI Health
The purpose of this research is to assess mucosal immune function responses in the gastrointestinal (GI) tract to twice-daily yogurt consumption.
- Conditions
- Yogurt Intake, Gastrointestinal Immune Function, Gut Microbiome, Gut Health
- Trial name
- NCT05931471
- Testing
- Yogurt Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Feasibility Study, Vaccine Immune Response
How Gut Health Affects Immune Responses to the Oral Rotavirus Vaccine in Adults in Zambia
The Rotavirus SpatioTrasncriptomics (Rota-Omics) study is a multidisciplinary research project aimed at understanding why oral rotavirus vaccines perform less effectively in some low- and middle-income countries, including…
- Conditions
- Feasibility Study, Vaccine Immune Response, Rota Virus Gastroenteritis, Transcriptomics
- Trial name
- Rota-Omics (NCT07626606)
- Testing
- Rotarix®,
- Where
- Zambia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Breast Cancer, Colon Cancer
The Efficacy of Health Partnership Program for Cancer Patients
The Objectives of this study is 1. To evaluate the efficacy for exercise, diet, and posttraumatic growth as a result of participating in tailored program (Health Partnership Program) for 24 weeks 2.
- Conditions
- Breast Cancer, Colon Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT01527409
- Testing
- Tailored health partnership program, Usual care and health education workshop
- Where
- 10 sites in South Korea
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea