Clinical trials: Intervention Intensity
Overweight and Obesity
Time-restricted Eating and High-intensity Interval Training for Metabolic Health in Adults With Overweight/Obesity
This study will investigate the effects of 12 months periodised time-restricted eating combined with high-intensity interval training compared with a control group on fat mass in adults with overweight/obesity.
- Trial name
- TREHIIT-3 (NCT07036562)
- Testing
- Time-restricted eating and high-intensity interval training
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Follow up, Parkinson Disease
Two-year Follow-up to High-intensity Multi-component Agility Intervention That Improves Clinical and Motor Symptoms of Parkinson's Disease
Individualization of exercise is recommended but rarely performed in patients with Parkinson's disease (PD). Unusually High Intensity and Individual Sensor Motor with Visuomotor Mobility Trainer The clinical symptoms, mobility…
- Conditions
- Follow up, Parkinson Disease, Rehabilitation
- Trial name
- NCT03193489
- Testing
- Follow-up, Post-treatment control, Control Parkinson group
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Molar Incisor Hypomineralization
Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization
Molar incisor hypomineralization (MIH) manifests as a qualitative, demarcated defect in tooth enamel of systemic origin, predominantly affecting one or more permanent first molars, and potentially extending to the incisors.
- Trial name
- LBIARHMI (NCT06426108)
- Testing
- Fluoride Varnishes, Low-Intensity Laser 1J, Low-Intensity Laser 2J
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Low Intensity Knee Gonalgia
Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.
- Trial name
- NCT01303432
- Testing
- Yogurt supplemented with Mobilee, Yogurt
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Premature, Retinopathy of Prematurity
Comfort Level in Premature Infants Undergoing Retinopathy of Prematurity Screening
Retinopathy of prematurity (ROP) screening is a routine yet painful procedure for premature infants, often necessitating pharmacological mydriasis.
- Conditions
- Premature, Retinopathy of Prematurity, Pain
- Trial name
- NCT07016984
- Testing
- standard phototherapy eye patches
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
Nausea, Emergency Department Patients
Effect of Antiemetic Timing on Nausea Severity and Patient Comfort in the Emergency Department
Nausea is a common symptom among patients presenting to the emergency department and can negatively affect patient comfort and clinical outcomes.
- Trial name
- ANTI-ED (NCT07523230)
- Testing
- Antiemetic Timing
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- muzeyyen ataseven
Major Depressive Disorder (MDD), Breast Cancer Survivor
Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan
Breast cancer is the most common cancer among women worldwide, and many survivors experience comorbid mental health conditions such as depression and anxiety, which can significantly worsen health outcomes and increase mortality.
- Trial name
- Moving On ABC (NCT07015944)
- Testing
- Non-specialist delivered Low intensity guided self-help (Khushi and Khatoon), Moving on After Breast Cancer (ABC) plus, Standardised pharmacological treatment (antidepressants)
- Where
- Pakistan
- Volunteers
- 26,376 people
- Sponsor
- Pakistan Institute of Living and Learning
Cancer, Cancer Pain
Clinical Pharmacists' Intervention on Pain Management in Cancer Patients
The study aims to evaluate the impact of clinical pharmacist intervention as a part of a multidisciplinary team to improve clinical outcomes of cancer patients with pain in comparison to standard care.
- Trial name
- PharmCaP (NCT05021393)
- Testing
- Clinical Pharmacist Intervention
- Where
- 2 sites in Nepal
- Volunteers
- 92 people
- Sponsor
- Monash University Malaysia
Non-Alcoholic Fatty Liver Disease, Gastrointestinal Microbiome
Exercise Study in Subjects With NAFLD
Non-Alcoholic Fatty Liver Disease is the most common cause of chronic liver diseases. The benign non-alcoholic fatty liver, characterized by excessive fat accumulation, can evolve into non-alcoholic steatohepatitis and liver…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Gastrointestinal Microbiome, Exercise
- Trial name
- BestTreat (NCT03995056)
- Testing
- high-intensity aerobic interval training
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- University of Eastern Finland
Hypertension (HTN), Obesity &Amp; Overweight
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
- Conditions
- Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
- Trial name
- MIND HIIT (NCT07130539)
- Testing
- MIND HIIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Texas Woman's University
Hypothyroidism
Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation
1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism. 2.
- Trial name
- NCT07636681
- Testing
- medication adherence based digital intervention
- Where
- Iraq
- Volunteers
- 80 people
- Sponsor
- University of Baghdad
Migraine
Synergistic Impact of Postural Correction Interventions and Sustained Natural Apophyseal Glides in Migraine
This study was conducted to evaluate the synergistic impact of postural correction interventions and sustained natural apophyseal glides on severity, quality of life and disability in patients with migraine.
- Trial name
- NCT07403175
- Testing
- Sustained Natural Apophyseal Glides, Postural Correction Exercises, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Dehydration, Symptom Cluster
Culturally Tailored Nurse Coaching Study for Cancer Symptom Management
The purpose of the study is to see whether or not a telephone/ text message intervention, delivered by a registered nurse, is helpful in managing symptoms and can also prevent dehydration caused by chemotherapy treatment when…
- Conditions
- Dehydration, Symptom Cluster, Quality of Life, Self Efficacy
- Trial name
- NCT04874584
- Testing
- CTNSM, Standard of Care Chemotherapy Education
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Miami
Breast Cancer
High Intensity Focused Ultrasound Guided by MRI as Thermic Destruction in Primitive Small Size Breast Cancer
This is a non-randomized, prospective phase II trial evaluating an innovative treatment, focused MRI-guided ultrasound, as thermic destruction in primitive small size breast cancer.
- Trial name
- MRHEATBREAST (NCT03126487)
- Testing
- HIGH INTENSITY FOCUSED ULTRASOUND
- Where
- France
- Sponsor
- Centre Antoine Lacassagne
Breast Cancer (Locally Advanced or Metastatic), Lymphedema Arm
The Effect of Self-Management Interventions Among Patients With Breast Cancer Related-Lymphedema
To manage lymphedema, it's important to be aware of symptoms and risk factors, evaluate the afflicted extremity, prevent infections, care for the skin, protect the extremity from trauma, maintain a healthy weight, and exercise…
- Trial name
- (BCRL) (NCT07803549)
- Testing
- Self-management Interventions
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- Al-Zaytoonah University of Jordan
Rheumatic Fever, Rheumatic Heart Disease in Children
ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months.
The ACT4RHD trial is a multicentre, pragmatic, multi-arm, open-label adaptive platform trial addressing multiple therapeutic questions in patients with ARF and carditis.
- Conditions
- Rheumatic Fever, Rheumatic Heart Disease in Children, Acute Rheumatic Fever, Rheumatic Heart Disease
- Trial name
- ACT4RHD (NCT07830108)
- Testing
- Hydroxychloroquine (HCQ), No Hydroxychloroquine (HCQ), Prednisone or Prednisolone
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 600 people
- Sponsor
- Starship Child Health, Te Toka Tumai Auckland
Diabetes, Physical Activity
Feasibility of REHIT in NDH Patients
The aim of this feasibility study was to describe and report data relevant to the acceptability of an exercise intervention (reduced-exertion, high-intensity interval training) in non-diabetic hyperglycaemia patients delivered in…
- Trial name
- NCT04011397
- Testing
- Exercise intervention, Usual care
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Huddersfield
Smoking Behaviors
Therapeutic Contact Intensity in a Psychological Smoking Cessation Intervention With an App
This randomized controlled trial intends to examine the efficacy of a smoking cessation intervention with an App according to the intensity of therapeutic contact. Participants will be assigned to one of three groups.
- Trial name
- TREATINTSMOKE (NCT06900985)
- Testing
- 8-sessions CBT + App, 4-sessions CBT+App, Smoking cessation App
- Where
- Spain
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Communication Disorders, Developmental Disabilities
Effects of Intensity of Early Communication Intervention
The purpose of the study is to determine if a more intensive application of communication intervention, i.e. 5 hours per week, will result in more frequent intentional communication acts, greater lexical density, and a better…
- Trial name
- NCT00723151
- Testing
- Milieu Communication Teaching
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas