Clinical trials: Intervention
Essential Hypertension
Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension
The trial is designed to assess the safety and investigation of the efficacy of a single oral dose of bisoprolol (Nerkardou - Nerhadou) oral dissolvable film (ODF) 5 \& 10 mg, and patients' compliance in the treatment of…
- Trial name
- BETTER (NCT05880056)
- Testing
- Nerkardou (5 mg) & (10 mg)
- Where
- Egypt
- Volunteers
- 406 people
- Sponsor
- Genuine Research Center, Egypt
Pregnancy-Induced Hypertension
Slow and Deep Breathing to Lower Blood Pressure in Women With Pregnancy-induced Hypertension
This study evaluates the effect of slow and deep breathing on lowering blood pressure in women with pregnancy-induced hypertension.
- Trial name
- NCT04059822
- Testing
- Slow and deep breathing
- Where
- 2 sites in United Kingdom
- Volunteers
- 1 people
- Sponsor
- Bournemouth University
Alveolar Ridge Augmentation, Bone Grafting
Antibiotic Prophylaxis Versus Placebo in Alveolar Bone Grafting: A Randomized Controlled Trial
Tooth extraction sites often require alveolar bone grafting to preserve ridge dimensions and improve conditions for future implant placement.
- Conditions
- Alveolar Ridge Augmentation, Bone Grafting, Antibiotic Prophylaxis
- Trial name
- ABXGRAFT (NCT07296302)
- Testing
- Amoxicillin 500 mg (prophylactic regimen)
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Agnaldo Rocha de Souza Junior
Transgenderism, HIV Infections
Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions
The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and…
- Trial name
- NCT05666102
- Testing
- Transgender men's perspectives on HIV risk and HIV prevention interventions
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Intellectual Disability, Developmental Disability
Written Language Intervention for Adults With Intellectual and Developmental Disabilities
The purpose of this study is to evaluate the effects of a written language intervention using functional texts for young adults with intellectual and developmental disabilities.
- Trial name
- NCT05851937
- Testing
- Written language intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Baylor University
Age-related Macular Degeneration
Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading Dose
The aim of this study is to compare the efficacy of early intervention of PDT combination compared with consecutive monthly treatment of intravitreal ranibizumab injections in PCV patients showing insufficient response with…
- Trial name
- NCT02864472
- Testing
- PDT, Ranibizumab, ranibizumab PRN
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery
Cardiac Cath Lab Staff Radiation Exposure
The objective of this randomized safety and observational study is to demonstrate CorPath GRX chronic total occlusion PCI is safe, and that Cardiac Catheterization Laboratory staff have no additional exposure to radiation when…
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery, Percutaneous Coronary Intervention
- Trial name
- SAFE-T (NCT03959072)
- Testing
- Robotic CTO PCI, Conventional (Manual) CTO PCI
- Where
- 3 sites in United States
- Volunteers
- 74 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Schizophrenia
Cue-based Intervention in Prospective Memory and Medication Adherence.
Medication adherence is a major challenge while treating patients with major mental illnesses like schizophrenia and schizoaffective disorder.
- Trial name
- NCT06474195
- Testing
- Cue based intervention, Treatment as Usual
- Where
- India
- Volunteers
- 104 people
- Sponsor
- University of Pittsburgh
Maternal; Alcohol Use, Affecting Fetus
Maternal Alcohol Reduction Intervention in South Africa [MaRISA]
This application proposes to develop and test a technology-based behavioral intervention to address maternal alcohol use in South Africa (SA).
- Trial name
- NCT05319977
- Testing
- Mobile incentive-based intervention
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- RTI International
Posttraumatic Stress Disorder, Tonic Immobility Response
Development and Evaluation of a Tonic Immobility Focused Psychoeducational Intervention
A randomized controlled trial is planned to evaluate a brief, web-based intervention intended to educate about tonic immobility (TI) within a sample of those who experienced TI in the context of a traumatic event.
- Trial name
- TIP (NCT05113277)
- Testing
- Tonic Immobility Psychoeducation (TIP), Health Education Training (HET)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Florida State University
HIV
Community-based Interventions to Increase HIV Testing and HIV Care Utilization
The purpose of this study is to conduct a cross-site evaluation of the Kaiser Permanente's Community-based Interventions to Increase HIV Testing and HIV Care Utilization Program, designed to support community-based interventions…
- Trial name
- NCT01867177
- Testing
- HIV testing, standard of HIV care, HIV care utilization
- Where
- United States
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Sleep Disturbance, Stress
Yoga for Persons With Severe Visual Impairment
This study aims to provide novel information on the feasibility of yoga interventions for secondary symptoms related to severe vision loss, such as sleep disturbances, negative mood states, fall risk and balance.
- Conditions
- Sleep Disturbance, Stress, Anxiety, Depression
- Trial name
- RPY (NCT01366677)
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Type 2 Diabetes
Cognitive Behavioral Intervention in Diabetes Self-Management
The proposed study is a two arm randomized controlled trial with longitudinal follow-up that compares cognitive behavioral interventions (ENHANCE) to a control group with attention.
- Trial name
- NCT01182701
- Testing
- Cognitive behavioral training
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Hawaii
Overuse Syndrome
Impact of an Intervention with a Narrative Approach in Overusers: a Clinical Trial
The goal of this clinical trial is to compare an intervention with a narrative therapy-based approach with standard care in overusers in general practice .
- Trial name
- NCT06258512
- Testing
- Intervention with a narrative approach.
- Where
- Spain
- Volunteers
- 264 people
- Sponsor
- Catalan Institute of Health
Suicidal Behavior
Brief Intervention and Contact Program Main Trial
Suicide is a significant public health concern and causes approximately 1.5% of all deaths in the general population in Canada. Research shows that for individuals with comorbid psychiatric illness and suicidal behaviour, the…
- Trial name
- BIC (NCT05656781)
- Testing
- Brief Intervention and Contact (BIC) based on Word Health Organization (WHO)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Childhood Asthma, Childhood Anxiety Disorder
COPE for Children With Asthma: Intervention for Children With Asthma
Children with a chronic condition are at a significantly higher risk for anxiety and depression than those without a chronic condition. Asthma is the most common childhood chronic condition.
- Conditions
- Childhood Asthma, Childhood Anxiety Disorder, Childhood Depression
- Trial name
- NCT03481673
- Testing
- COPE for Asthma
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Calcaneus ; Fracture ; Traumatology
Minimally Invasive Procedure Versus Conservative Treatment in the Management of Calcaneal Joint Fractures
Calcaneal fractures, which affect the heel bone, are the most common type of tarsal fractures and often occur in young people, leading to long recovery times and significant social and economic consequences.
- Trial name
- IMPACT (NCT06779305)
- Testing
- Minimally invasive surgical application of Calcanail®, Immobilisation by cast boot
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Smoking Cessation
ISTAPS: A Stepped Primary Care Smoking Cessation Intervention
Primary care centers can play a very important role in helping people to stop smoking. There is a large body of research on the effectiveness of specific interventions especially addressed to people who want to stop smoking.
- Trial name
- NCT00125905
- Testing
- Advice, Motivational Interviewing, Nicotine Gum and Patch
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Postoperative Recovery
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Bronchoscopy is a promising technology for lung and bronchus disease detection and therapy. However, this procedure is associated with a relatively high risk of hypoxemia, coughing, wheezing, and dyspnea.
- Trial name
- NCT05643066
- Testing
- 0.1 mg/kg esketamine, 0.2 mg/kg esketamine, 0.9% saline
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Fujian Provincial Hospital
Diabetes, Diabetes Mellitus, Type 2
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
This trial is conducted in the United States of America (USA). The purpose of this study is to compare the effectiveness and safety of a biphasic insulin aspart standard titration regimen when coupled with dietary intervention to…
- Trial name
- INITIATE plus (NCT00101751)
- Testing
- biphasic insulin aspart, dietary regimen
- Where
- United States
- Volunteers
- 4,877 people
- Sponsor
- Novo Nordisk A/S