Clinical trials: Interstitial Cystitis and Bladder Pain Syndrome
Interstitial Cystitis, Chronic Interstitial Cystitis
Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations
The objective of this study is to test the idea that Pulsed Electromagnetic Field (PEMF) therapy will serve as a safe therapeutic modality that can effectively be administered simultaneously with bladder instillations of a…
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT06013449
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Sponsor
- Wake Forest University Health Sciences
Painful Bladder Syndrome, Interstitial Cystitis
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Purpose: 1. To demonstrate better symptoms control (pain, urinary urgency and frequency) with sacral neuromodulation (SNM) in patients with interstitial cystitis /painful bladder syndrome (IC/PBS) using a stimulation frequency of…
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction
- Trial name
- NCT01312259
- Testing
- Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Pelvic and Sexual Health Institute
Interstitial Cystitis
The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome
The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT01985880
- Where
- 2 sites in South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Chronic Fatigue Syndrome, Fibromyalgia
Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome
The purpose of this study is: 1. To identify specific set of proteins in the cerebrospinal fluid (fluid surrounding the brain and the spinal cord), that are believed to be seen in Chronic fatigue syndrome (CFS) patients, but not…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Illness, Multiple Chemical Sensitivity
- Trial name
- NCT00810329
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Interstitial Cystitis, Bladder Pain Syndrome
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or…
- Trial name
- NCT05276466
- Testing
- Polymerase Chain Reaction and Next-Generation DNA Sequencing
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- MicroGenDX
Bladder Diseases, Interstitial Cystitis
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
This is a randomized clinical trial study to test the efficacy and safety of amitriptyline in the treatment of patients newly diagnosed with painful bladder syndrome (PBS).
- Trial name
- IC01 (NCT00124306)
- Testing
- Amitriptyline
- Where
- 10 sites in United States, Canada
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cystitis, Interstitial
An Effectiveness and Safety Study of PF-04383119 for the Treatment of Pain in Interstitial Cystitis
The purpose of this study is to determine whether PF-04383119 is effective in the treatment of pain associated with interstitial cystitis.
- Trial name
- NCT00601484
- Testing
- PF-04383119
- Where
- 34 sites in United States
- Volunteers
- 65 people
- Sponsor
- Pfizer
Interstitial Cystitis
Platelet-Rich Plasma (PRP) Injection in Treatment of Interstitial Cystitis
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating chronic disease of unknown etiology characterized by urgency frequency and suprapubic pain at full bladder.
- Trial name
- NCT03104361
- Testing
- Platelet-Rich Plasma
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Interstitial Cystitis, Recurrent Cystitis
Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation
This study aims to evaluate a catheter-free method for delivering medications directly into the bladder, known as intravesical instillation, which is commonly used to treat conditions such as interstitial cystitis/bladder pain…
- Conditions
- Interstitial Cystitis, Recurrent Cystitis, Haemorrhagic Cystitis, Bladder Cancer
- Trial name
- NOCATIN (NCT06719232)
- Testing
- Catheter-Free Intravesical Instillation with a special syringe adapter
- Where
- 2 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Jahn Ferenc South Pest Teaching Hospital
Bladder Pain Syndrome, Interstitial Cystitis
Low-dose Naltrexone for Bladder Pain Syndrome
Interstitial cystitis/Bladder Pain Syndrome (IC/PBS) is a constellation of symptoms of pelvic discomfort that includes both bladder-related pain as well as urinary frequency, urgency, and nocturia in the absence of an…
- Trial name
- NCT04450316
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Bladder Cancer, Interstitial Cystitis
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
The goal of this clinical trial research study is to evaluate the impact of preoperative oral immunonutrition (IN) on post-operative complications in patients undergoing a cystectomy.
- Conditions
- Bladder Cancer, Interstitial Cystitis, Painful Bladder Syndrome, Neurogenic Bladder
- Trial name
- INCyst (NCT05726786)
- Testing
- Immunonutrition
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Irritable Bowel Syndrome, Ulcerative Colitis
Efficacy of Gralise® for Chronic Pelvic Pain
This study is done to investigate the pain relieving effects of the study drug Gralise (a novel long acting gabapentinoid) for people who experience chronic pelvic pain.
- Conditions
- Irritable Bowel Syndrome, Ulcerative Colitis, Interstitial Cystitis, Prostatitis
- Trial name
- NCT01678911
- Testing
- Gralise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shirley Ryan AbilityLab
Interstitial Cystitis, Painful Bladder Syndrome
Genetics of Interstitial Cystitis
The cause of interstitial cystitis is unknown. However, it tends to run in some families suggesting that there may be a genetic susceptibility to the disease.
- Trial name
- magic (NCT00237081)
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Painful Bladder Syndrome, Interstitial Cystitis
Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
A double-blind, placebo-controlled study to evaluate changes in pain, urgency and urinary frequency following administration of URG101 compared to placebo.
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT00517868
- Testing
- URG101
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Urigen
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Interstitial Cystitis
Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis
To evaluate the efficacy and safety of intravesical instillation of Lipotoxin for the treatment of IC/BPS
- Trial name
- NCT02247557
- Testing
- Liposome encapsulated BoNT-A, BOTOX 200U in normal saline, Normal saline
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Interstitial Cystitis, Painful Bladder Syndrome
Use of Preemptive Pudendal Nerve Block Prior to Hydrodistention for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)
Interstitial cystitis/Painful bladder syndrome (IC/PBS) is a chronic debilitating condition that severely impacts between 2.7 and 6.5 percent of women in the United States.
- Trial name
- NCT02517996
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Johns Hopkins University
Interstitial Cystitis, Bladder Pain Syndrome
Comparing the Effect of Fulguration Versus Fulguration and Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome
This study is a randomized controlled trial. Subject population is adult patients with Hunner-type interstitial cystitis. The objective of this study is to compare the therapeutic effect between the two surgical modality; TUF…
- Trial name
- NCT03987594
- Testing
- Transurethral fulguration of the Hunner lesion, Combination treatment of bladder hydrodistension and transurethral fulguration of the Hunner lesion
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Yonsei University
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC
A comparative study of subjective outcomes following intravesical treatment of interstitial cystitis (IC) is lacking in the literature.
- Trial name
- NCT05223244
- Testing
- bupivacaine, triamcinolone, and heparin (BTH), dimethyl sulfoxide (DMSO)
- Volunteers
- 83 people
- Sponsor
- Endeavor Health