Clinical trials: Interstitial Cystitis and Bladder Pain Syndrome
Chronic Interstitial Cystitis, Painful Bladder Syndrome
Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Pilot study to determine feasibility for treating patients with two chronic inflammatory conditions of the urinary bladder: chronic interstitial cystitis and recurrent urinary tract infections using a standardized hyperbaric…
- Conditions
- Chronic Interstitial Cystitis, Painful Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- HBOTCICrUTI (NCT03143920)
- Testing
- Hyperbaric Oxygen Therapy-
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Diego
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis
Diagnostic Challenges in IC (and Male CPPS)
The etiology and pathogenesis of interstitial cystitis (IC) and its related condition in men, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has remained elusive.
- Conditions
- Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis, Asymptomatic Inflammatory Prostatitis, Painful Bladder Syndrome
- Trial name
- NCT00672087
- Testing
- Genomic and proteomic biomarker discovery
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Auricular Acupressure Therapy for Patients With IC/BPS
The purpose of this study is to determine the feasibility of administering auricular acupressure for patients with interstitial cystitis/bladder pain syndrome (IC/BPS), and evaluating the efficacy of auricular acupressure to…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Urologic Diseases, Chronic Pain
- Trial name
- IC/BPS (NCT05857020)
- Testing
- Auricular Acupressure
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Painful Bladder Syndrome
An Effectiveness And Safety Study Of PD 0299685 For The Treatment Of Symptoms Associated With Interstitial Cystitis
The purpose of this study is to determine whether PD 0299685 is effective in the treatment of symptoms associated with interstitial cystitis/painful bladder syndrome, such as pain, urinary urgency and frequency.
- Trial name
- NCT00739739
- Testing
- PD 0299685 at 15mg BID, PD 0299685 at 30mg BID
- Where
- 44 sites in United States, Canada and 4 more
- Volunteers
- 161 people
- Sponsor
- Pfizer
Interstitial Cystitis
Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions
The etiology of bladder pain syndrome is unknown. Therefore the management is directed to pain relief, as bladder pain is believed to drive both voiding frequency and nocturia.
- Trial name
- NCT01437579
- Testing
- intratrigonal injection of botulinum toxin, cystoscopy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Moscow State University of Medicine and Dentistry
Interstitial Cystitis
Urinary Biomarkers Characteristic to Interstitial Cystitis
This is a retrospective study of urine samples stored in the Beaumont BioBank for future research. The urine samples will be drawn from the urine back with patients previously diagnosed with severe interstitial cystitis (IC)…
- Trial name
- NCT00971568
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
Interstitial Cystitis
Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine the safety and pharmacokinetics of TTI-1612 in women with interstitial cystitis/bladder pain syndrome.
- Trial name
- NCT01559961
- Testing
- TTI-1612
- Where
- 4 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Trillium Therapeutics Inc.
Bladder Pain Syndrome, Interstitial Cystitis
Acupuncture First for IC/BPS
The goal of this clinical trial is to learn if acupuncture in addition to behavioral changes can better treat in women with bladder pain syndrome (also known as interstitial cystitis) that have not received other treatments.
- Trial name
- NCT06366269
- Testing
- Acupuncture, Behavioral management, Physical therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University Hospitals Cleveland Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Identifying Genetic Causes of IC/BPS
Interstitial cystitis (IC), also called Bladder Pain syndrome (BPS) is a common condition with no known cause or cure. Twin studies and family accounts have suggested that the condition may be genetic or passed down (inherited)…
- Trial name
- NCT00389142
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Interstitial Cystitis, Bladder Pain Syndrome
The Female Microbiome in Patients Undergoing Bladder Instillation Therapy
The underlying pathophysiology for BPS/IC is currently an active area of research. There is speculation that there may be alteration in the bladder and vaginal microbiome that contributes to the symptomatology of BPS/IC, however…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Microbial Colonization
- Trial name
- NCT05414305
- Testing
- Heparin & Alkalinized Lidocaine Bladder Instillation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Walter Reed National Military Medical Center
IC, Hunner Type Interstitial Cystitis
The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis With Hunner's Lesions
To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis with Hunner's lesions to reduce cicatricial changes in the bladder caused by electrocoagulation and to prevent secondary bladder shrinkage with a…
- Conditions
- IC, Hunner Type Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT07459790
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- JSC NextGen
Interstitial Cystitis, Bladder Pain Syndrome
Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome
Recognition of interstitial cystitis (IC)/bladder pain syndrome (BPS) is increasing. There is a dire need to develop effective treatment options for these patients as it manifests as more than a physical disease, affecting…
- Trial name
- NCT04401176
- Testing
- Heparin & Alkalinized Lidocaine Bladder Instillation, Onabotulinum Toxin A
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Walter Reed National Military Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common, chronic, and debilitating condition in women. Preliminary evidence suggests that IC/BPS pain can be reduced applying non-invasive repetitive transcranial magnetic…
- Trial name
- IcBrainStim (NCT04734847)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Bladder Pain Syndrome
The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)
The purpose of this study is to assess the efficacy of gefapixant (AF-219/MK-7264) in female participants with moderate to severe pain associated with interstitial cystitis/bladder pain syndrome (IC/BPS) after 4 weeks of…
- Trial name
- NCT01569438
- Testing
- Gefapixant
- Where
- 41 sites in United States
- Volunteers
- 107 people
- Sponsor
- Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Interstitial Cystitis
Intravesicular Onabotulinumtoxin A in Interstitial Cystitis
The purpose of this research study is to identify the optimal usage of Onabotulinumtoxin A in interstitial cystitis. Onabotulinumtoxin A, more commonly known by the trade name Botox®, is a medication that comes from the bacteria…
- Trial name
- NCT02297100
- Testing
- Onabotulinumtoxin A, injections upper aspect of trigone of urinary bladder, injections on posterior bladder wall excluding the trigone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Interstitial Cystitis, Chronic, Painful Bladder Syndrome
Clinical Features and Histologic Findings in Bladder Pain Syndrome/Interstitial Cystitis
Objectives- to find out whether a correlation exists between denudation of urothelium and diagnosic delay in patients with BPS / IC, secondary aim was to search a correlation between impact of symptoms evaluated with ICSI-ICPI…
- Trial name
- HistologyIC (NCT03069053)
- Where
- 4 sites in Italy
- Volunteers
- 57 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Interstitial Cystitis, Painful Bladder Syndrome
Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
- Trial name
- NCT06096597
- Testing
- Clarix Flo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Sheyn
Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic
Evaluation of Hyivy Floora in Managing Interstitial Cystitis/Bladder Pain Syndrome/High-tone Pelvic Floor Dysfunction
The purpose of this study is to test the safety and effectiveness of the Floora Pelvic Rehabilitation Vaginal Dilator in females with Interstitial Cystitis/ Bladder pain Syndrome (IC/BPS) and High-tome Pelvic Floor Dysfunction…
- Conditions
- Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic, High Tone Pelvic Floor Dysfunction
- Trial name
- NCT07038512
- Testing
- Floora Pelvic Rehabilitation Vaginal Dilator
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Bladder Pain Syndrome
Engage 24: Evaluation of the Safety and Effectiveness of URG101 in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine if the combination product (URG101) is safe and effective versus its individual components (Heparin Sodium and Lidocaine Hydrochloride) for the treatment of Interstitial Cystitis/Bladder…
- Trial name
- NCT02591199
- Testing
- URG101, Lidocaine, Heparin
- Where
- 11 sites in United States
- Volunteers
- 91 people
- Sponsor
- Urigen