Clinical trials: Intensive Care Units (ICUs)
Pressure Ulcer (PU), Hemofiltration
Evaluation of Pressure Injury Risks in Hemofiltration
Purpose: Patients treated in intensive care units are at high risk of developing pressure injuries due to their critical illnesses as well as many risk factors such as immobility, changes in level of consciousness, hemodynamic…
- Conditions
- Pressure Ulcer (PU), Hemofiltration, Intensive Care Units (ICUs)
- Trial name
- NCT07825727
- Testing
- Identifying the risks of pressure injuries
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Ogr. Uyesi Naile
Pressure Injury, Reliability and Validity
Adaptation of the Intensive Care Unit-specific Pressure Injury Risk Scale to Turkish (RAPS-ICU)
The aim of this study was to evaluate the translation, cross-cultural fit, and psychometric properties of the ICU-specific pressure injury risk scale
- Conditions
- Pressure Injury, Reliability and Validity, Intensive Care Units (ICUs), Assessment Scale
- Trial name
- NCT06908512
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Harran University
Intensive Care Units (ICUs)
FRench-speAking Icu (Intensive Care Unit) Nutritional Survey
Assessment of nutritional practices in french intensive care units.
- Trial name
- FRANS (NCT02599948)
- Testing
- no intervention
- Volunteers
- 1,215 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critically Ill, Hyperglycemia
Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2
The Purpose of this study is to: 1. Introduce the refined, validated, and safe computerized bedside decision support tool for blood glucose management in critically ill adult and pediatric ICU patients that was studied in Phase 1…
- Trial name
- NCT00654797
- Testing
- glucose control with computer generated recommendations
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- Intermountain Health Care, Inc.
Decision Making, Terminal Illness
Organ Donation and End-of-life Decisions
Variation in organ donation after brain death (DBD) per million population varies markedly between countries, within country regions, between and within intensive care units (ICU).
- Conditions
- Decision Making, Terminal Illness, Tissue and Organ Procurement
- Trial name
- NCT04131140
- Where
- Sweden
- Volunteers
- 12,072 people
- Sponsor
- Swedish Intensive Care Registry
Delirium, Anxiety and Depression
Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in Intensive Care Unit
Artificial intelligence (AI), now an integral part of healthcare services and presents numerous opportunities. Customized treatment plans, clinical decision support systems, predictive analysis for disease prevention, patient…
- Conditions
- Delirium, Anxiety and Depression, Intensive Care Units (ICUs), Artificial Intelligence (AI)
- Trial name
- AINURSE-OP (NCT07171944)
- Testing
- Structured orientation program, Human Nurse
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Koç University
Intensive Care Units (ICUs), Muscle Atrophy or Weakness
Neuromuscular Electrical Stimulation in Critically Ill Patients Aged 80 and Over
The aim of this clinical trial is to evaluate the effectiveness of Medium-Frequency Neuromuscular Electrical Stimulation, in combination with standard physical therapy, compared to standard physical therapy alone, on muscle mass…
- Conditions
- Intensive Care Units (ICUs), Muscle Atrophy or Weakness, Old and Very Old People
- Trial name
- NMES-ICU80 (NCT07127991)
- Testing
- Medium Frequency Neuromuscular Electrical Stimulation (NMES), Standard physical therapy
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad de La Frontera
ICU Patients, Surgical
Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs
The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive…
- Conditions
- ICU Patients, Surgical, Nutrition Intervention, Enteral Nutrition
- Trial name
- NCT07337798
- Testing
- Guideline Implementation
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Failed or Difficult Intubation, Sequela, Intubation; Difficult
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
- Trial name
- NEAR4KIDs (NCT02493478)
- Where
- 87 sites in United States, Australia and 9 more
- Volunteers
- 150,000 people
- Sponsor
- Children's Hospital of Philadelphia
COVID-19 Acute Respiratory Distress Syndrome
Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources
Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the…
- Trial name
- NCT05450120
- Testing
- Functional Rehabilitation, Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Sao Carlos
Daptomycin, Real-world Study
Real-world Daptomycin Use in Chinese ICUs
Analyze the effectiveness and safety of Daptomycin(Jiangsu Hengrui Medicine Co., Ltd) in Gram-positive infections in Chinese Intensive Care Units by using the real-world data platform, https://rws.scccmqc.com.
- Conditions
- Daptomycin, Real-world Study, Intensive Care Unit
- Trial name
- NCT03588637
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Carbapenem Resistant Enterobacteriaceae Infection, Artificial Intelligence
A Novel Approach to Antimicrobial Resistance: Machine Learning Predictions for Carbapenem-Resistant Klebsiella in ICUs
The aim of this study to predict carbapenem resistant Klebsiella spp. earlier in our patients monitored in our Intensive Care Unit in the future, using artificial intelligence.
- Conditions
- Carbapenem Resistant Enterobacteriaceae Infection, Artificial Intelligence, Intensive Care Unit
- Trial name
- ICU (NCT05985057)
- Testing
- Artificial intelligence
- Where
- Turkey (Türkiye)
- Volunteers
- 289 people
- Sponsor
- Kocaeli University
Nurse's Role
Views of Nurses on Alarm Fatigue in ICUs
This study focused on determining the views of nurses on alarm fatigue and its reduction in adult intensive care units.
- Trial name
- NCT05163340
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Akdeniz University
Critical Illness
SET-to-Meet; Pilot Testing of a Nurse-led Intervention
While interdisciplinary family meetings are evidence-based and part of usual care, this study seeks to test a novel set of implementation strategies (the SET-to-Meet intervention) to improve adherence to best practice guidelines…
- Trial name
- SET-to-Meet (NCT03904524)
- Testing
- SET-to-Meet
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- University of Pittsburgh
Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema
Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials
The goal of this clinical trial is to evaluate the evolution of a cardiac ultrasound index (E/E') during 3 spontaneous breathing trials in Intensive Care Unit (ICU) adults (over 18 years) patients at risk for weaning failure.
- Conditions
- Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema, Weaning Failure of Mechanical Ventilation, Spontaneous Breathing Test
- Trial name
- ATARI (NCT06923267)
- Testing
- No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial, Pressure Support Spontaneous Breathing trial, Humidified High Flow Spontaneous Breathing Trial
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Dexmedetomidine, Ketamine
Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial
This investigator-initiated, randomized, controlled, single-blind, superiority trial aims to assess the efficacy and safety of esketamine combined with dexmedetomidine for the management of agitation or delirium in intensive care…
- Conditions
- Dexmedetomidine, Ketamine, Analgesia, Respiratory Therapy
- Trial name
- SEED-NIRS (NCT07377981)
- Testing
- Esketamine combined with dexmedetomidine, Dexmedetomidine
- Where
- China
- Volunteers
- 356 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Enteral Feeding, Ventilator-Associated Pneumonia
Impact of Intermittent and Continuous Enteral Feeding on Ventilator-associated Pneumonia in Pediatric ICUs
Mechanical ventilation has become one of the most important supportive treatment methods to save the life of critically ill children over time.
- Trial name
- NCT02973347
- Testing
- Intermittent enteral feeding, Continuous enteral feeding
- Volunteers
- 400 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Organ Failure, Multiple
Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs
This study will assess the impact of FTIRS typing on the spread of ESBL-E in intensive care units
- Trial name
- ECLA'IR (NCT05872152)
- Testing
- FTIR results
- Where
- France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Caen
Mechanical Ventilation, Pulmonary Rehabilitation
Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.
This international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide.
- Conditions
- Mechanical Ventilation, Pulmonary Rehabilitation, Intensive Care Units (ICUs), Quality of Life (QOL)
- Trial name
- REPOrt (NCT07093125)
- Where
- Italy
- Volunteers
- 2,400 people
- Sponsor
- Universita degli Studi di Genova
Pediatric Patient (1m-21y), ICU Admission
Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial
The primary goal of this project is to determine whether normalizing hyperglycemia is a safe approach to improve multisystem organ function in critically ill children requiring intensive care.
- Conditions
- Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
- Trial name
- PedETrol (NCT01116752)
- Testing
- Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Indiana University