Clinical trials: Intensive Care Units
Non-ST Elevated Myocardial Infarction
Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit Admission
Favourable in-hospital outcome is observed in numerous patients after Non ST myocardial infarction (NSTEMI) with invasive strategy but European guidelines proposed systematic intensive care unit monitoring up to 24 h in lower…
- Trial name
- SELECTNSTEMI (NCT05153889)
- Testing
- Hospitalized in Intensive care unit, Hospitalized in General cardiology ward
- Where
- 3 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Montpellier
Intensive Care Pediatric
Corticosteroids Before Extubation in Pediatric Intensive Care Unit
Fifty to 60% of children admitted to a pediatric intensive care unit (PICU) are placed under invasive mechanical ventilation (MV) at least once during their stay.
- Trial name
- COBEX-PED (NCT06722118)
- Testing
- Dexamethasone IV
- Where
- 15 sites in France
- Volunteers
- 348 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diaper Dermatitis
Neonatal Intensive Care Unit (NICU) Diaper Dermatitis: Prevention and Treatment With Airtime
The purpose of this study is to investigate the use of 3-5 minutes air therapy for the prevention and treatment of diaper dermatitis in infants 30 weeks and older receiving care in the neonatal intensive care unit (NICU).
- Trial name
- NCT06958003
- Testing
- Air Therapy
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- TriHealth Inc.
Critically Ill, Hemodialysis
Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD)
Daptomycin is an antibiotic that is affective against many strains of antibiotic resistant microorganisms. This antibiotic would be appropriate for use in the intensive care unit (ICU) considering the severity of illness and high…
- Trial name
- NCT00663403
- Testing
- Daptomycin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Michigan
Sleep Disorders Not Due to A Substance or Known Physiological Condition
Validity and Reliability of the French Translation of the Richards-Campbell Questionnaire
The validation of a sleep questionnaire (translated into French from a source questionnaire in English) will provide a reliable and easily administered tool for assessing sleep quality in intensive care, enabling better…
- Trial name
- French-RCSQ (NCT06945874)
- Testing
- Validation of sleep quality by the Richards-Campbell Sleep Questionnaire (RCSQ) in french version
- Where
- 2 sites in France
- Volunteers
- 190 people
- Sponsor
- University Hospital, Rouen
Medication Errors, Patient Safety
Impact of Computerized Physician Order Entry on Medication Prescription Errors in the Intensive Care Unit: a Controlled Cross-Sectional Trial.
Device: computerized physician order entry. We wanted to investigate if the introduction of a computerized intensive care unit system reduced the incidence and severity of medication prescription errors (MPEs).
- Trial name
- NCT00287274
- Testing
- computerized physician order entry
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University Hospital, Ghent
Fever
Fever Observational Study
To inform the feasibility of conducting a study to test different temperature thresholds at which clinicians deliver interventions to reduce fever (i.e.
- Trial name
- NCT03028818
- Where
- United Kingdom
- Volunteers
- 3,960 people
- Sponsor
- Intensive Care National Audit & Research Centre
Postpartum Depression (PPD), Self-Efficacy
NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)
The study's objective is to conduct a Phase II randomized controlled trial examining the preliminary efficacy of the VoiceLove app compared to usual care on maternal postpartum depression in mothers with infants admitted to the…
- Conditions
- Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient
- Trial name
- NURTURE (NCT07214597)
- Testing
- VoiceLove mobile phone application
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Neonatal Convulsions, Newborn Seizure Disorders
Clinical Profile And Outcomes Of Neonatal Convulsions In The Neonatal Intensive Care Unit At Assiut University Children's Hospital
Neonatal convulsions are seizures that occur during the first 28 days of a newborn's life. They are considered a medical emergency and often indicate an underlying problem in the brain, such as lack of oxygen at birth…
- Conditions
- Neonatal Convulsions, Newborn Seizure Disorders, Seizures
- Trial name
- NCT07274410
- Testing
- Management of Neonatal Convulsions
- Volunteers
- 139 people
- Sponsor
- Assiut University
Peripheral Intravenous Line
Effectiveness of Peripheral Intravenous Line Securement With Splint in Neonates
Splints are often used in neonatal intensive care units (NICUs) to immobilize the limb and stabilize the catheter, theoretically reducing complications by minimizing movement at the catheter site.
- Trial name
- NCT07589010
- Testing
- Splint, Neonates were not supported with a splint
- Where
- Pakistan
- Volunteers
- 192 people
- Sponsor
- Muhammad Aamir Latif
Cirrhosis With Septic Shock
Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit
The Patient evaluated in Emergency room since admission and detailed history and clinical examination done .The in hospital cases where sepsis is the culprit and shifted to Intensive Care Unit (ICU) in view of septic shock were…
- Trial name
- NCT01836224
- Testing
- Terlipressin, Noradrenaline
- Where
- India
- Volunteers
- 84 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Cardio-Respiratory Distress
Early Mobilization: Evaluation of Feasibility and Security in Pediatric Intensive Care Unit
The purpose of this study is to evaluate the feasibility and the security of early mobilization of infants in pediatric intensive care.
- Trial name
- NCT02958124
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Atrial Fibrillation
Long-term Recurrence Rates of Atrial Fibrillation Following New-onset Atrial Fibrillation During ICU Admission
The Primary Objective of the study is to establish the One-year recurrence rates of atrial fibrillation (AF) following new-onset atrial fibrillation during intensive care unit (ICU) admission.
- Trial name
- NCT05151523
- Volunteers
- 100 people
- Sponsor
- Katia Orvin
Epilepsy, Neurologic Disorder
Cenobamate in the Intensive Care Unit
The CENOBITE study will be conducted as a multi-center trial involving X leading centers from the Critical Care EEG Monitoring Consortium (CCEMRC).
- Trial name
- CENOBITE (NCT06352723)
- Testing
- Cenobamate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Intensive Care Units, Pediatric
Therapeutic Follow-up of Antibiotics in Pediatric Intensive Care
Currently, recommendations for antibiotic testing (ATS) in adult intensive care have been published. The 2018 SFAR and the Abdul- Aziz et al expert conference recommend routine testing for β-lactams, aminoglycosides, linezolid…
- Trial name
- STAR-P (NCT05354635)
- Testing
- Antibiotics Dosing
- Where
- Reunion
- Volunteers
- 280 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pain
Impact of Hypnosis During Invasive Procedure in Intensive Care Unit
Pain during ICU stay remains one of the major complaints for patients. Beside pain intensity, well described by patients' self reports, pain distress, which is an emotional experience, cannot be treated with usual analgesia.
- Trial name
- HYPNOICU (NCT04399850)
- Testing
- Hypnosis group
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Kidney Injury, Chronic Kidney Insufficiency
Comparison of Two Different External Clearance Markers - Mannitol and Iohexol for Measuring Glomerular Filtration Rate
GFR is the best parameter of the real kidney function. Measurements, however are time-consuming and have limited capacity. Patients treated in the intensive care units often have more than one organ-insufficiency and acute kidney…
- Trial name
- GFR (NCT06238310)
- Testing
- Comparison of two external marker substance for measuring glomerular filtration rate
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Katalin Kiss
Endotracheal Tube Position
Pilot Study for Verifying Endotracheal Tube Repositioning Using Ultrasound
The investigators will compare the response to oral endotracheal tube repositioning as measured by chest x-ray and measured by the air-wave device.
- Trial name
- NCT02407158
- Testing
- SonarMed Airwave Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Hemophagocytic Lymphohistiocytosis (HLH), Macrophage Activation Syndrome (MAS)
Investigation of Ferritin in Critically Ill Patients With Hemophagocytic Lymphohistiocytosis
Retrospective analysis of ferritin, outcome and HLH-criteria in critically ill patients.
- Conditions
- Hemophagocytic Lymphohistiocytosis (HLH), Macrophage Activation Syndrome (MAS), Hemophagocytic Syndromes
- Trial name
- FERRITS (NCT02854943)
- Volunteers
- 2,623 people
- Sponsor
- Gunnar Lachmann
Work-Related Condition
Working Shift Organization, Caregivers' Satisfaction and Quality of Life at Work, and Performance.
This is a prospective, non-randomized, multicenter, observational national study, involving centers with different working shift organizations.
- Trial name
- IOTA-REA (NCT03875521)
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris