Clinical trials: Intensive Care Unit Patients
Fibrosing Interstitial Lung Disease
Prospective Cohort of Patients With Fibrosing Interstitial Lung Disease Admitted for Acute Respiratory Failure
This prospective, multicenter study focuses on patients with fibrosing interstitial lung diseases (ILD) admitted to intensive care units (ICUs) for acute respiratory failure (ARF).
- Trial name
- PIDREA (NCT06855004)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suspected Infection With Vancomycin Susceptible Bacterial Strains
Pharmacokinetics of Vancomycin in ICU Patients
Vancomycin is frequently under-dosed in ICU patients during the first 24-48 hours of treatment. Glomerular hyperfiltration syndrome, increased drug volume of distribution, vasopressor use, male sex and hypoalbuminemia are…
- Trial name
- PK-VANCO-ICU (NCT02844192)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Transfusion Related Complication
Transfusion Strategy in Hematological Intensive Care Unit
Patients with acute hematological disease (acute leukemia, aplastic anemia, hematopoietic stem cells autologous or allogeneic ...) and hospitalized in an intensive care unit hematology require compensation of anemia and…
- Trial name
- 1VERSUS2CGR (NCT02461264)
- Testing
- Single red blood packed cells Transfusion, Two packed red blood cells Transfusion
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Caen
Respiratory Failure, Treatment Outcome
Pattern of Admission and Outcome of Patients Admitted to the Intensive Care
The study was a retrospective observational cohort where patient medical record review was done and data were gathered on 419 cases.
- Trial name
- ICU (NCT05591209)
- Where
- 2 sites in Ethiopia
- Volunteers
- 419 people
- Sponsor
- Haramaya Unversity
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis and Maintenance of Local Skin Microclimate
To explore the feasibility of Jefcare Sterile Medical Sheets in preventing incontinence-associated dermatitis and maintaining a stable local skin microclimate in adult patients in the intensive care unit.
- Trial name
- NCT06509932
- Testing
- Jefcare Sterile Medical Sheets, MoliCare Premium Bed Mats
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sir Run Run Shaw Hospital
Critical Illness, Intensive Care
Critical Illness Outcomes Study
We will test whether the way that an intensive care unit is organized can influence patient related outcomes such as mortality. We will test whether who works in the ICU, and how the ICU is managed will affect the care received…
- Conditions
- Critical Illness, Intensive Care, Intensive Care Unit
- Trial name
- CIOS (NCT01109719)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Continuous Glucose Measurement
A Comparative Study to Evaluate the Accuracy and Safety of the GlySure Continuous Intravascular Glucose Monitoring System Versus Intermittent Blood Glucose Monitoring
The purpose of this study is to evaluate the system performance of the GlySure Continuous Glucose Monitoring (CGM) system in patients admitted to the Surgical Intensive Care Unit.
- Trial name
- NCT01942902
- Testing
- Continuous Glucose Monitoring System
- Where
- 2 sites in India
- Volunteers
- 38 people
- Sponsor
- GlySure
Mechanical Ventilation, Weaning Failure
Comparison of Weaning Parameters and Diaphragm Thickness Changes
Determining the appropriate timing for mechanical ventilator weaning in intensive care unit patients is critical to avoid complications related to early or late weaning, including weaning failure.
- Conditions
- Mechanical Ventilation, Weaning Failure, Intensive Care Unit (ICU) Patients, Diaphragm Dysfunction
- Trial name
- Weaning (NCT06967623)
- Testing
- diaphragm ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Tarık Durna
Mechanical Ventilation, Weaning Failure
Ventilatory Settings and Monitoring Variables Associated With Weaning Failure in Critically Ill Patients
Mechanical ventilation (MV) is essential in managing acute respiratory failure. Its duration is a crucial aspect since both, unnecessary prolongation and premature withdrawal have deleterious effects on patient outcomes in the…
- Conditions
- Mechanical Ventilation, Weaning Failure, Weaning Failure of Mechanical Ventilation, Intensive Care Unit ICU
- Trial name
- WEAN-FAIL (NCT06683781)
- Where
- Argentina
- Volunteers
- 1,077 people
- Sponsor
- Hospital Italiano de Buenos Aires
Critical Illness, Geriatric Assessment
Geriatric Assessment at Discharge From the Intensive Care Unit in Patients Aged 75 Years and Older: a Feasibility Study
The number of patients aged over 75 continues to grow, and, according to INSEE, will represent almost 10% of the French population in 2021, an increase of 2.4 points since 2000.
- Conditions
- Critical Illness, Geriatric Assessment, Older People, Frailty
- Trial name
- PreGEDI (NCT06513130)
- Testing
- Geriatric assessment in the 7 days following ICU discharge., No geriatric assessment in the 7 days following ICU discharge.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Critical Care
Effect of Glutamine and Vitamin C on Interleukin-6 and Clinical Outcomes in Surgical Intensive Care Unit Patients
Background \& Aims. Glutamine is a conditional essential amino acid that was found in reduced plasma amount in Intensive Care Unit (ICU) patients.
- Trial name
- NCT03166956
- Testing
- Glutamine and vitamin C enteral supplement
- Volunteers
- 41 people
- Sponsor
- Chung Shan Medical University
Intensive Care Units
Efficacy of Sound Insulation and Music Therapy on the Comfort of Mechanically Ventilated Patients Admitted to Intensive Care Unit
The purpose of this study is to assess the effect of sound insulation and music therapy on the comfort of mechanically ventilated patients admitted to intensive care unit measured by the Bispectral Index (BIS), the Ramsay…
- Trial name
- NCT02040051
- Testing
- Sound isolation / Music therapy
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Fever
Fever Algorithm Development of a Non-invasive Wearable Core Body Temperature Sensor System in Intensive Care Unit Patients
Background and Rationale: The gold standard to assess fever, is to conduct invasive intravascular, esophageal or bladder thermistor core body temperature (CBT) measurements.
- Trial name
- NCT04182945
- Testing
- Data collection for algorithm development
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- greenTEG AG
Post Intensive Care Unit Syndrome, Psychological Trauma
Positive Suggestions Via MP3 Messages
The purpose of this study is to assess the use of an audio recording containing positive suggestion as a means to provide needed psychological support to critically ill patients in a feasible and reliable manner.
- Conditions
- Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression
- Trial name
- NCT04437095
- Testing
- Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Mayo Clinic
COVID-19, Intensive Care Unit Syndrome
COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units
Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU).
- Trial name
- TOCCIP (NCT04433325)
- Where
- 2 sites in France
- Volunteers
- 37 people
- Sponsor
- Rennes University Hospital
Anemia
Research Into the Treatment of Anemia for Critically Ill Patients Admitted to Intensive Care Units (ICU)
Erythropoietin (EPO) is a hormone produced in the kidney. Its function is to stimulate the production of red cells in the bone marrow.
- Trial name
- NCT00091910
- Testing
- Epoetin alfa
- Volunteers
- 1,460 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetes Insipidus, Neurohypophyseal, Copeptin Blood Levels
The Trend of Copeptin Levels and Its Clinical Value for Postoperative CDI in Pediatric Patients After NSI in ICU
Central diabetes insipidus (CDI),a disease caused by the decrease of AVP (a hormone involved in the control of water-electrolyte balance ) secretion and characerized by polyuria, is a common complication after neurosurgerical…
- Conditions
- Diabetes Insipidus, Neurohypophyseal, Copeptin Blood Levels, Copeptin, Neurosurgical Intervention
- Trial name
- NCT06742060
- Testing
- serum copeptin levels
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Fudan University
Septic Shock
Transcutaneous Electric Muscle Stimulation (TEMS) in Septic Patients
A growing number of critically ill patients survive intensive care to be discharged from hospital. However, critical illness and prolonged bedrest are associated with muscle wasting with subsequent implications for recovery of…
- Trial name
- NCT01071343
- Testing
- Transcutaneous electrical muscle stimulation
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tracheostomy Complication
"Outcomes of Tracheostomy Done for Patients Admitted in Anesthesia Intensive Care Units of Assiut University Hospital"
This study was undertaken to Identify the factors affecting the outcomes of tracheostomy done in ICU for patients subjected to prolonged intubation and ventilation and to suggest guidelines to control: 1.
- Trial name
- PITS (NCT03431389)
- Testing
- Tracheostomy tube
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Assiut University
Covid19, Acute Respiratory Failure
Survival Rates and Longterm Outcomes After COVID-19
The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs' is a national observational study, including patients admitted to a Norwegian ICU between March 2020 and March 2021.
- Conditions
- Covid19, Acute Respiratory Failure, Acute Respiratory Distress Syndrome, Post Intensive Care Unit Syndrome
- Trial name
- NCT04601090
- Testing
- ICU treatment
- Where
- Norway
- Volunteers
- 860 people
- Sponsor
- Oslo University Hospital