Clinical trials: Intensive Care Unit (ICU)
COPD, COPD Exacerbation
Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.
Patients admitted in ICU may require invasive mechanical ventilation, using a mechanical ventilator and an endotracheal tube. In ICU, a prolonged duration of invasive mechanical ventilation may be responsible for…
- Conditions
- COPD, COPD Exacerbation, Ventilated Patients, Ventilator-Associated Pneumonia (VAP)
- Trial name
- SLEECOP (NCT06653933)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Grenoble
Cardiac Arrythmias
Pilot Study for the Tight K Study
The primary purpose of this pilot study will be feasibility of recruitment. However, in order to further inform a full randomised controlled trial (RCT), information on the incidence of atrial fibrillation (AF) and other…
- Trial name
- TightK (NCT03195647)
- Testing
- Potassium
- Where
- 2 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- Barts & The London NHS Trust
Intensive Care Unit Acquired Weakness, Critical Illness
Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise
Up to 60% of patients admitted to the Intensive Care Unit (ICU) with a prolonged stay in the ICU develop complications such as intensive care unit acquired weakness (ICUAW) characterized by limb and respiratory muscle weakness.
- Trial name
- NCT05279547
- Testing
- Constant-load bed-cycling exercise, Interval bed-cycling exercise
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Intensive Care Unit, Inflammation
The New ICU Prognostic Score APACHE-INf
Intensive care units (ICUs) aim to provide specialized care for patients with high morbidity and mortality risks. To effectively identify patients requiring urgent diagnosis and treatment, various scoring systems have been…
- Conditions
- Intensive Care Unit, Inflammation, Nutritional Deficiency
- Trial name
- NCT05955547
- Testing
- Prognosis Scoring
- Where
- Turkey (Türkiye)
- Volunteers
- 15,000 people
- Sponsor
- Bursa City Hospital
Kidney Failure, Critically Ill
Hemodialysis Without Anticoagulation in Intensive Care Unit
The purpose of this study is to determine the safety and operative efficacy of intermittent hemodialysis without anticoagulation with saline flushes or Nephral 400ST in patients at high risk of bleeding
- Conditions
- Kidney Failure, Critically Ill, Hemorrhage
- Trial name
- NCT00242398
- Testing
- AN69 ST
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Départemental
Pain
Pain Management of Intensive Care Unit Patients
The purpose of this study is to evaluate the effect of an algorithm, where ICU patients pain are assessed systematically with valid pain assessment tools and where pain is treated after pain intensity score.
- Trial name
- NCT01599663
- Testing
- Pain management algorithm
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Ostfold Hospital Trust
Newborn, Anxiety
Stress and Anxiety Levels of Mothers Lying in the Baby Newborn Intensive Care Unit
Although coronaviruses (CoV) cause mild infections in the community, such as colds, they can also cause more severe infections. There are many subspecies of coronaviruses that can pass from animals to humans and can be…
- Trial name
- NCT04386798
- Testing
- survey work
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Critical Illness, Sepsis
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
Introduction- Hospital acquired infections (HAI) are a major cause of morbidity and mortality and increase health care costs. Critically ill patients are particularly susceptible to these infections and have an even higher…
- Conditions
- Critical Illness, Sepsis, Septic Shock, Ventilator Associated Pneumonia
- Trial name
- SuDDICU (NCT02389036)
- Testing
- SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic
- Where
- 3 sites in Australia, Canada and 1 more
- Volunteers
- 20,010 people
- Sponsor
- The George Institute
Intensive Care Unit Delirium, Pain
Decreasing Delirium Through Music in Critically Ill Older Adults
Critically ill older adults admitted to the intensive care unit (ICU) are at a higher risk to develop delirium, which predisposes them to longer lengths of ICU and hospital stay, increased in-patient mortality, and higher risk of…
- Conditions
- Intensive Care Unit Delirium, Pain, Anxiety, Intensive Care Acquired Cognitive Impairment
- Trial name
- DDM (NCT04182334)
- Testing
- Slow Tempo Music, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Indiana University
Preterm Infants
Physiological Safety and Behavioral Comfort of Swaddle Bathing in Preterm Infants
Background and Purpose: Bathing is a routine but essential part of care for preterm infants in the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT07522892
- Testing
- Swaddle Bathing, Conventional Tub Bathing
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung University of Science and Technology
Preterm, Pain
Reducing Pain During Orogastric Tube Placement in Preterm
The aim of this study is to determine the effectiveness of 3 different methods (breast milk pacifier, sucrose pacifier and pacifier) in reducing pain caused by Orogastric Tube (OGT) insertion in preterm newborns by monitoring…
- Conditions
- Preterm, Pain, Nursing Caries
- Trial name
- NCT05430100
- Testing
- The effect of usıng breast mılk pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng sucrose pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Length of Stay
Alberta Collaborative QI Strategies to Improve Outcomes of Moderate and Late Preterm Infants (ABC-QI Trial)
The ABC-QI Trial aims to implement collaborative quality improvement (QI) strategies to standardize care for 32-36 week infants in Level 2 and 3 Neonatal intensive care units (NICUs) across the province of Alberta.
- Trial name
- ABC-QI (NCT05231200)
- Testing
- QI Team Building, QI education, Standardized care bundle- respiratory care
- Where
- 12 sites in Canada
- Volunteers
- 9,500 people
- Sponsor
- University of Calgary
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Acute Kidney Injury
Continuous Venovenous Hemodiafiltration Versus Sustained Low-efficiency Hemodialysis for Critically Ill Patients With Acute Kidney Injury in Intensive Care Unit
The investigators conducted a comparison trial between SLED and CRRT in critically ill patients to evaluate the outcome for all cause mortality at 30 day .
- Trial name
- NCT02879201
- Testing
- Slow efficiency dialysis
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Nosocomial Infections
Efficacy of Copper in Reducing Health-Acquired Infections in a Pediatric Intensive Care Unit
Healthcare-acquired infections (HAI) cause substantial patient morbidity and mortality. Commonly touched items in the patient care environment harbor microorganisms that may contribute to HAI risk.
- Trial name
- NCT01678612
- Testing
- Copper-alloy surfaced objects
- Where
- Chile
- Volunteers
- 1,012 people
- Sponsor
- Codelco
Postnatal Growth
Silicone Earplugs for VLBW Newborns in Intensive Care
The purpose of this study was to determine the effects of individual noise reduction using silicone earplugs for very low birthweight newborns in neonatal intensive care on growth and development.
- Trial name
- NCT00565357
- Testing
- Silicone Earplugs, Control
- Volunteers
- 34 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Mechanical Ventilation, Intensive Care Medicine
Intelligent Lung Support in the Intensive Care Unit
The aim of this observational study is to test the IntelliLung decision support system based on artificial intelligence. This system is intended to help to set the ventilator.
- Trial name
- IntelliLung (NCT06595602)
- Testing
- Artificial intelligence based decision support system (AI-DSS); software
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 530 people
- Sponsor
- Technische Universität Dresden
Critically Ill
Ultrasound Guided Central Venous Vascular Access - Novel Needle Navigation Technology Compared With Conventional Method
Background: Central venous catheter (CVC) insertion is a very common procedure in the intensive care setting. A recent international guidelines advocated the use of ultrasound for routine internal jugular CVC insertion.
- Trial name
- NCT03214575
- Testing
- Conventional method, GPS Method
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Sarcopenia, Covid19
Sarcopenia and Related Factors in Coronavirus Disease 2019 (COVID-19) Following Intensive Care
The primary aim of this study is to evaluate the patients who had pneumonia or severe acute respiratory distress syndrome (ARDS) due to COVID-19 in terms of sarcopenia and related factors following Intensive Care Unit (ICU).
- Conditions
- Sarcopenia, Covid19, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05474157
- Testing
- Standard care treatment for COVID-19 in Intensive Care Unit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Antibiotic Resistant Infection, Nosocomial Infection
Inulin for Infections in the Intensive Care Unit
Normal gut bacteria prevent colonization and subsequent infection with MDR organisms (MDROs) through competition for resources and other mechanisms.
- Conditions
- Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders
- Trial name
- NCT03865706
- Testing
- Inulin Oral Suspension, Broad-spectrum antibiotics
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Columbia University