Clinical trials: Intensive Care Unit, open to volunteers
Pressure Injuries, Skin Failure
Barrier Functions oF Skin in ICU: SKIN-BAR
This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration…
- Conditions
- Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
- Trial name
- SKIN-BAR (NCT07560683)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Koç University
Diaper Dermatitis
Neonatal Intensive Care Unit (NICU) Diaper Dermatitis: Prevention and Treatment With Airtime
The purpose of this study is to investigate the use of 3-5 minutes air therapy for the prevention and treatment of diaper dermatitis in infants 30 weeks and older receiving care in the neonatal intensive care unit (NICU).
- Trial name
- NCT06958003
- Testing
- Air Therapy
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- TriHealth Inc.
Non Bleeding Patients With Thrombocytopenia
Platelet Transfusion Thresholds in Non-Bleeding Patients
This is a study of platelet transfusion thresholds in patients with thrombocytopenia without bleeding and benifits of transfusion in those critically ill patients to prevent bleeding
- Trial name
- NCT07915284
- Testing
- Platlet transfusion
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Bacteremia, Sepsis Bacterial
Prospective Validation of GRADY: A Machine Learning Model for Early Sepsis and Bacteremia Detection in ICU Patients
This study aims to prospectively validate the GRADY prediction models, which use machine learning algorithms to estimate the risk of gram-negative bacteremia and sepsis in intensive care unit (ICU) patients based on routinely…
- Trial name
- NCT07126106
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Well-Being, Psychological, Engagement
The Impact of the Family Room App on Caregivers
Engaging families in patient care during serious illness can enhance care quality, reduce social isolation, boost satisfaction, and lower healthcare costs.
- Conditions
- Well-Being, Psychological, Engagement, Satisfaction, Consumer
- Trial name
- NCT06463158
- Testing
- Family Room Application
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Acute Respiratory Failure (ARF), Non Invasive Ventilation (NIV)
Music Therapy During NIV Implantation in Pediatric Intensive Care Units
Non-invasive ventilation makes it possible to avoid intubation and improve patients' quality of life. However, pain is associated with discomfort and could lead to failure of this technique.
- Trial name
- MusiNIV (NCT06848218)
- Testing
- Music Therapy, Setting Up NIV
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Montpellier
Cardiac Surgery
Study of Readmission to Intensive Care Unit After Cardiac Surgery in Heart Hospital of Assiut University : Risk Factors .Reasons and Early Out Come
Cardiac Surgery is any surgical procedure applied to heart and its connected vessels especially thoracic aorta; representing a treatment option for significant cardiac diseases .
- Trial name
- NCT07083297
- Volunteers
- 89 people
- Sponsor
- Assiut University
Burnout Syndrome
Burnout Syndrome in the Intensive Care Unit Before and During a Palliative Care Trial
One hundred ICU doctors, nurses and psychologists from 4 / 8 ICUs of the Greek group of the 28 European units participating in the EPIC stepped-wedge trial (ClinicalTrials.gov NCT06605079) will each complete the same four-part…
- Trial name
- BURNOUT-EPIC (NCT07069010)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Acute Respiratory Failure, Mechanical Ventilation
A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication
- Trial name
- TIME (NCT06042621)
- Where
- 5 sites in United States
- Volunteers
- 7,818 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Spontaneous Breathing Trial in ICU, Spontaneous Breathing Trial
Effectiveness of Pet-Robotic Intervention in Intensive Care Unit Patients
This study aims to develop a novel nursing intervention involving robotic pet companionship to reduce anxiety in patients undergoing spontaneous breathing trials.
- Trial name
- NCT07163247
- Testing
- Robotic pet (PARO) companionship
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital
Longitudinal, Genomic Stability
Epidemiology and Overtime Genomic Evolution of Klebsiella Pneumoniae and Enterobacter Cloacae Complex (ECC) in Stools of ICU's Patients
Infections are one of the major threats for inpatients, even more for patients hospitalized in intensive care units (ICUs). They are responsible for an important increase of morbidity and mortality rates as well as a burst of…
- Conditions
- Longitudinal, Genomic Stability, Klebsiella Infections, Enterobacter Cloacae Infection
- Trial name
- NormandyKlebs (NCT07744321)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Ventilation Modes, Mechanical Ventilation
Effectiveness of Ventilation Modes in Intensive Care: A Comparison of Mandatory Minute Ventilation and Synchronized Intermittant Mandatory Ventilation Using Bioelectrical Impedance Tomography
Synchronized Intermittent Mandatory Ventilation (SIMV) is a commonly used ventilatory mode available in many modern ventilators, frequently applied in intensive care units for patients requiring invasive mechanical ventilation.
- Conditions
- Ventilation Modes, Mechanical Ventilation, Critical Illness, Respiratory Support
- Trial name
- NCT06961227
- Testing
- No investigational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Harran University
Acute Kidney Injury, Renal Replacement Therapy
Effects of Variation of Sodium Dialysate in ICU
Intermittent hemodialysis/diafiltration is a current renal replacement therapy (RRT) institued for ICU patients with AKI. For a better clinical tolerance, iinternational guidelines advise to use cold dialysate, increase duration…
- Trial name
- NADIRA (NCT03329313)
- Testing
- Lowering sodium concentration dialysate, Highing sodium concentration dialysate
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
fNIRS for Disorders of Consciousness
The goal of this observational study is to learn whether functional near-infrared spectroscopy (fNIRS) can measure brain activity in healthy adults and in people with disorders of consciousness (DoC) in the neuro-intensive care…
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State
- Trial name
- NCT07485361
- Testing
- Functional Near-Infrared Spectroscopy Monitoring
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Patients in ICU, Delirium in the Intensive Care Unit
A Prospective Observational Study Using the FAM-CAM
The goal of this observational study is to learn whether family members can help identify signs of delirium in adult patients who are staying in the intensive care unit.
- Conditions
- Patients in ICU, Delirium in the Intensive Care Unit, Family
- Trial name
- NCT07694687
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shanghai Zhongshan Hospital
Neonatal Intensive Care Unit
Critical Care Optimized Pediatric and Neonatal Quantitative Neuromonitoring
The detection and appropriate treatment of seizures significantly impact the neurological prognosis of patients in intensive care.
- Trial name
- COPeQ (NCT06726408)
- Testing
- Neuromonitoring with 10 electrodes
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Nantes University Hospital
Critically-ill Patients
Immunosuppression and Intensive Care Unit-acquired Multidrug-resistant Bacteria
Antimicrobial resistance AMR is an emerging global threat to human health, and intensive care units (ICUs) are a 'hot spot' for the emergence and diffusion of multidrug-resistant (MDR) bacteria.
- Trial name
- TANGERINE (NCT06652126)
- Testing
- Microbiological examinations.
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille
Venous Congestion
VEXUS-REA : Evaluation of Ultrasound Parameters of Venous Congestion in Patients in a Medical Intensive Care Unit
Shock is a common and serious cause of admission to intensive care. Vascular filling is one of the cornerstones of shock treatment, aimed at increasing cardiac output and restoring adequate organ perfusion through rapid…
- Trial name
- VEXUS-REA (NCT07438015)
- Testing
- Venous ultrasound (inferior vena cava, portal vein, suprahepatic vein, and renal vein to calculate the VEXUS score ; femoral vein and popliteal vein)
- Where
- France
- Volunteers
- 525 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pressure Ulcer (PU)
The Effect of Pulse Oximeter Probe Replacement Interval on Pressure Injury Development in Intensive Care Patients
Patients admitted to intensive care units (ICUs) are at increased risk of medical device-related pressure injuries (MDRPIs) due to the prolonged use of monitoring devices.
- Trial name
- NCT07704710
- Testing
- Pulse Oximeter Probe Repositioning Every 2 Hours, Pulse Oximeter Probe Repositioning Every 4 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Emine Arici Parlak