Clinical trials: Intensive Care Unit
Refusal of Treatment
Effects of Italian Law 219/2017 in Pediatric Intensive Care Units
This study aims to investigate pediatric intensive care providers' knowledge, perceptions, and experiences with Law 219/2017 by means of a national multicentric non-interventional cross-sectional study.
- Trial name
- NCT07093047
- Testing
- Questionnaire administration
- Where
- 3 sites in Italy
- Volunteers
- 172 people
- Sponsor
- University of Padova
Community Acquired Pneumonia, Bronchiolitis
HVNI vs CPAP in Children With Acute Respiratory Distress
Acute breathing problems are a common reason for children to be admitted to the pediatric intensive care unit, and many of these children need breathing support without a breathing tube.
- Trial name
- P-HVNI-CPAP (NCT07336121)
- Testing
- High Velocity Nasal Insufflation (HVNI), Nasal Continuous Positive Airway Pressure (Nasal CPAP)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Critical Illness
A Trial of Enteral Colostrum on Intestinal Permeability in Critically Ill Patients
The effects of colostrum on intestinal permeability in critical ill patients has not been investigated. In current trial, intensive care unit patients with enteral feeding will receive either enteral colostrum or maltodextrin as…
- Trial name
- NCT03186716
- Testing
- Colostrum, Maltodextrin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- National Nutrition and Food Technology Institute
Premature Birth, Fragility
Wireless MicroPremVitals Button Sensor in the NICU
A wireless and miniaturized vital sign (ECG, SpO2, Skin Temperature) sensor system, MicroPremVitals Button Sensors was developed by the Dr.
- Conditions
- Premature Birth, Fragility, Apnea of Prematurity, Bradycardia Neonatal
- Trial name
- NCT07732257
- Testing
- Wireless MicroPremVitals Button Sensor System
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Positive-Pressure Respiration
Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit
Protective ventilation - combining a low tidal volume (between 6 and 8 ml/kg) and alveolar recruitment (AR) manoeuvres repeated every 30 minutes - is currently the standard of care for decreasing morbidity associated with…
- Trial name
- RHERA1 (NCT02805036)
- Testing
- echocardiography, Arterial oximetry
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Critical Illness, Delirium
Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study
An ICU admission is stressful for not only patients but their families as well. Research has shown that involving family members during a loved one's ICU stay can be helpful for them, but there is not clear direction on the best…
- Trial name
- FIT-ICU (NCT06071793)
- Testing
- Family involvement
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Renal Failure, Bacterial Infections
Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis
The study's primary objective is to determine plasma and dialysis fluid concentrations in patients prescribed ceftazidime-avibactam as the standard treatment for their infection and requiring continuous venovenous…
- Conditions
- Renal Failure, Bacterial Infections, Critical Illness
- Trial name
- NCT03243864
- Testing
- Ceftazidime-avibactam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Temple University
Low-Birth-Weight Infant, Premature Infants
Analyzer of Human Milk: Applicability in Clinical Practice in Order to Achieve the Best Nutrition for Infants
An observational and prospective study involving about 30 healthy lactating mothers whose preterm infant(s) is/are hospitalized at Neonatal Intensive Care Unit after childbirth and who can provide enough maternal milk (3mL) to be…
- Trial name
- MISTU (NCT02971904)
- Testing
- human milk collection
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Early Life Nutrition Brazil
Muscle Atrophy, Muscle Weakness
Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Post-intensive care syndrome (PICS) encompasses persistent physical, cognitive, and psychiatric symptoms following ICU discharge, commonly triggered by serious conditions such as respiratory failure, sepsis, and mechanical…
- Conditions
- Muscle Atrophy, Muscle Weakness, Blood Flow
- Trial name
- NCT06238609
- Testing
- Intervention Group, Control Group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bijan Najafi, PhD
Delirium
Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours in the incident ICU…
- Trial name
- DahLIA (NCT01151865)
- Testing
- Dexmedetomidine
- Where
- 7 sites in Australia
- Volunteers
- 96 people
- Sponsor
- Austin Health
Respiratory Distress Syndrome, Newborn
Feasibility Study of Placement and Surfactant Administration Through a Preterm Size Laryngeal Mask Airway in Very Low Birth Weight Neonates With Respiratory Distress Syndrome
Surfactant administration via a supraglottic airway device or laryngeal mask airway (SALSA) is a minimally invasive method of instilling surfactant in the trachea during spontaneous breathing and after applying nasal continuous…
- Trial name
- NCT06606444
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways
- Where
- Vietnam
- Volunteers
- 45 people
- Sponsor
- Karolinska Institutet
Enteral Nutrition, Microbial Colonization
Hand Hygiene Practices and Microbial Contamination on Feeding Tubes and Other Components of Feeding Systems
Enteral feeding tube (EFT) and component of feeding systems can serve as a reservoir of microorganisms, and the main reason is inappropriate hand hygiene practices.
- Conditions
- Enteral Nutrition, Microbial Colonization, Adherence
- Trial name
- NCT04240132
- Testing
- Adherence to Hand Hygiene
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Neonatal Hearing Impairment
Neonatal Hearing Screening in Assiut Hospital
Hearing loss is one of the most common congenital anomalies. Early Intervention at or before 6 months of age allows a child with impaired hearing to develop normal speech and language.Auditory brainstem response , otoacoustic…
- Trial name
- NCT03251638
- Volunteers
- 300 people
- Sponsor
- Assiut University
High Bleeding Risk, Hemorrhage
Efficacy of Intermittent Pneumatic Compression (IPC) on Venous Thromboembolism Incidence in Intensive Care Unit (ICU) Patients With High Bleeding Risk
This multicentre open-label randomized parallel-group trial aims to evaluate the association intermittent pneumatic compression + elastick stockings versus elasting stockings alone on symptomatic or asymptomatic venous…
- Trial name
- CIREA1 (NCT00740844)
- Testing
- Intermittent pneumatic compression of the lower limbs
- Where
- 10 sites in France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Brest
Myocardial Perfusion Imaging
Real-Time Myocardial Perfusion Echocardiography in the ICU
This study is being done to find out if and how much the use of RTMPE improves a provider's confidence in the diagnosis they assign.
- Trial name
- NCT03173716
- Testing
- Definity
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Bronchial Aspiration
Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay
Patients of age >18 yo, admitted to the ICU through the surgery department from 2AUG2021 to 1AUG2022 will be divided into three groups: 1.
- Trial name
- NCT05284084
- Testing
- Bed Head elevation, H2 blockers and mouth wash, Data collection for comparison
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Marshall University
Critical Illness
Rehabilitation Gaming System for Intensive Care Units
Admission to an Intensive Care Unit (ICU) is a potentially traumatic experience for a mentally vulnerable person. Beyond the stress and anxiety associated with the ICU environment and medical procedures, survivors of critical…
- Trial name
- RGS-ICU (NCT06267911)
- Testing
- Cognitive stimulation and psychological support (RGS-ICU)
- Where
- 3 sites in Spain
- Volunteers
- 93 people
- Sponsor
- University of the Balearic Islands
Respiratory Failure, Intensive Care Pediatric
The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubation Process.
The extubation process is critical to the future health outcomes of the pediatric patient because it tests the ability of the respiratory system to function without the support of mechanical ventilation.
- Trial name
- NCT06591533
- Testing
- Music therapy + standard care, Standard Care (in control arm)
- Where
- 2 sites in Colombia
- Volunteers
- 82 people
- Sponsor
- Claudia Aristizábal
Stress, Psychological, Preterm Infants
Multimedia Admission Orientation in NICU
The effect of a multimedia admission orientation on the parental stress, uncertainty, and knowledge of primary caregivers of high-risk infants in a neonatal intensive care unit: a quasi-randomized controlled trial study.
- Conditions
- Stress, Psychological, Preterm Infants, Intensive Care Units, Neonatal, Education
- Trial name
- NCT05214248
- Testing
- a multimedia admission orientation
- Where
- Taiwan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Sepsis, Infection
The Extended Study of Prevalence of Infection in Intensive Care IV
The goal of this observational study is to learn how common infections are in intensive care units (ICUs) around the world and how they are treated. The study will look at all adults in the ICU during a single 24-hour period.
- Trial name
- EPIC IV (NCT07309549)
- Volunteers
- 10,000 people
- Sponsor
- Universidad de la Sabana