Clinical trials: Intensive Care Patients
COVID-19, Acute Respiratory Distress Syndrome
Physical Rehabilitation in ICU in ARDS Patients With COVID-19
The primary aim of this study is to evaluate the effect of physical rehabilitation performed in intensive care unit on the range of joint motions and muscle strength of survivors following discharge from intensive care unit in…
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Rehabilitation, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04435080
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Koç University
Invasive Candidiasis
Pharmacokinetics of Micafungin in Patients of Intensive Care Units
Invasive fungal infections (IFIs) are a frequent cause of morbidity and mortality in high-risk patients, such as immunocompromised patients.
- Trial name
- MI-K (NCT02164890)
- Testing
- micafungin
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Burn Injury, Burns
Foreign-National Burn Patients in a Border-Region Burn Center
This retrospective cohort study will evaluate burn patients hospitalized and treated at the Burn Center of Gaziantep City Hospital between October 2023 and June 2026.
- Trial name
- NCT07673796
- Volunteers
- 1,400 people
- Sponsor
- Gaziantep City Hospital
COVID-19, Intensive Care Unit
Zooming in on Cerebral Abnormalities in Severely Affected COVID-19 Patients
Brain injury is one of the complications in COVID-19 intensive care unit (ICU) survivors, though the precise underlying mechanism is unclear.
- Trial name
- ZoomCOVID (NCT05197296)
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Maastricht University Medical Center
ICU Stay, Muscle Atrophy
Weaning Assessment by Peripheral Muscle Ultrasonography
In this study, which aims to investigate the relationship between the weaning process and respiratory muscles-assessed via ultrasonographic measurement of peripheral muscle thickness-in patients over the age of 18 who have been…
- Conditions
- ICU Stay, Muscle Atrophy, Ultrasonography, Weaning Mechanical Ventilation
- Trial name
- NCT07860879
- Testing
- Ultrasonography of peripheral muscle (rectus femoris or vastus intermedius), Ultrasonography of diaphragma
- Volunteers
- 100 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Delirium
Retrospective Evaluation of Delirium Data From Previous Study Patients for Studies at the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF
Evaluation of several studies of the Clinic for Anesthesiology and Intensive Care Medicine CCM/CVK/CBF to create a register with the delirium data from anesthesiology study patients between 18 - 100 years.
- Trial name
- NCT05913531
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Charite University, Berlin, Germany
Respiratory Failure
Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
A growing body of knowledge has documented that the diaphragm, the primary muscle of breathing, atrophies and weakens within days of instituting mechanical ventilation support.
- Trial name
- NCT01108575
- Testing
- IMST
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida
Myasthenia Gravis, Guillain-Barre Syndrome
Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis
Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols.
- Trial name
- GUIMAUVE (NCT07022028)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Critical Illness, Sleep Quality
Effects and Mechanism of Guided Virtual Reality Autogenic Meditation on ICU Sleep
Background: Sleep disturbance is a common complaint reported by critically ill patients, which may in turn prolong the length of intensive care unit (ICU) stay, and increase the risks of delirium and mortality.
- Trial name
- NCT05196672
- Testing
- Virtual reality and eye mask
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Taipei Medical University
Acute Respiratory Distress Syndrome (ARDS), Hypoxemia
Early Prone Positioning and Clinical Outcomes in Non-Intubated Acute Respiratory Distress Syndrome (ARDS) Patients
This study aimed to evaluate the effectiveness of early prone positioning in improving clinical outcomes among non-intubated patients with Acute Respiratory Distress Syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Hypoxemia, Respiratory Failure, Non-Intubated Patients
- Trial name
- EPP-ARDS (NCT07133022)
- Testing
- Early Prone Positioning Protocol, Standard ICU Care
- Where
- Palestinian Territories
- Volunteers
- 100 people
- Sponsor
- Loai Muawiah Zabin
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Satisfaction, Patient
Learning Excellence Program and Improvement of Quality Care
Improving the quality of care is a daily goal in pediatric intensive care units. Measuring patient and family satisfaction is recognized as an indicator of quality of care.
- Trial name
- RECOMPENSE (NCT05707195)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Intensive Care Unit Sleep Disruption
Gabapentin for Sleep in Critically Ill Patients
Sleep disruption in the intensive care unit (ICU) is a common comorbidity associated with patient morbidity and distress. There are no recommended pharmacologic interventions for sleep promotion, and many pharmacologic solutions…
- Trial name
- NCT04631510
- Testing
- Gabapentin 300 mg PO at 8 PM
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Tufts Medical Center
Hematological Malignancy, Acute Respiratory Failure
Prognosis of Hematological Cancer Patient Underwent Mechanical Ventillation
This observational cohort aimed to re-evaluate the outcome of hematologic cancer patients admitted to the intensive care unit of Mansoura oncology center through a cohort study as regards their need for mechanical ventilation…
- Conditions
- Hematological Malignancy, Acute Respiratory Failure, Mechanical Ventilation
- Trial name
- NCT02562105
- Testing
- Mechanical ventilation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Hematologic Malignancy
Outcomes of Critically Ill Patients With Hematologic Malignancies
The investigators sought to report the outcomes of patients with haematological malignancies admitted to the intensive care units and to define pre-intensive care units prognostic factors for in-hospital all-cause mortality.
- Trial name
- NCT06410066
- Testing
- no intervention
- Volunteers
- 144 people
- Sponsor
- Soroka University Medical Center
Psoas Hematomas
Spontaneous Haematomas of Psoas Occurring in Intensive Care
Psoas hematomas are a rare and potentially lethal pathology whose incidence in resuscitation is unknown. The pathophysiology of this pathology is not known to date.
- Trial name
- NCT03452631
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Sepsis, Septic Shock
Ionized Calcium as a Severity Marker in Septic Shock Patients
Sepsis is a serious condition where the body has an extreme, dysregulated response to an infection, often leading to life-threatening organ dysfunction.
- Conditions
- Sepsis, Septic Shock, Hypocalcemia
- Trial name
- NCT07812051
- Volunteers
- 160 people
- Sponsor
- Assiut University
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism)
Retrospective observational cohort study including all patients admitted for toxidermia (Lyell syndrome, Stevens-Johnson Syndrome (SJS), or other extensive skin destruction) to the Burn unit of the adult ICU of the Lausanne burn…
- Trial name
- TEN metabolism (NCT05320653)
- Testing
- Medical nutrition
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
ICU Patients, Under Mechanical Ventilation
Syndrome and Aspiration Pneumonia in Intensive Care
Inhalation is a common condition in patients with impaired their awareness requiring protection of the upper airway by endotracheal intubation. This inhalation may lead to chemical pneumonitis and/or bacterial pneumonia.
- Conditions
- ICU Patients, Under Mechanical Ventilation, In State of Coma (Define by Glasgow ≤ 8), No Antibiotic Treatment
- Trial name
- SPIRE (NCT01881672)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Acute Lung Injury, Acute Respiratory Distress Syndrome
Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients
sRAGE, the soluble form of the receptor for advanced glycation end products, is a novel marker of alveolar epithelial type I cell injury, but is also involved in acute systemic inflammation.
- Conditions
- Acute Lung Injury, Acute Respiratory Distress Syndrome, Severe Sepsis, Septic Shock
- Trial name
- NCT00811629
- Testing
- sRAGE
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand