Clinical trials: Intensive Care
Intensive Care, Oral Care
Oral Care Apparatus for Intubated Patients
There are several practical challenges in providing oral care to intubated patients. The presence of an endotracheal tube often makes it difficult to thoroughly evaluate the oral cavity, and there is a risk of tube displacement…
- Conditions
- Intensive Care, Oral Care, Intubated ICU Patients
- Trial name
- Oral Care (NCT06709183)
- Testing
- Intervention-Control, Control - intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Catheter-Related Infections, Central Venous Catheters
Advanced Dressings for CVC Infection Prevention in PICU
Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections…
- Conditions
- Catheter-Related Infections, Central Venous Catheters, Bloodstream Infection, Pediatric Intensive Care Units
- Trial name
- NCT07175116
- Testing
- 3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated), Conventional transparent polyurethane dressing
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University of Seville
Intensive Care Unit Delirium, Pain
Decreasing Delirium Through Music in Critically Ill Older Adults
Critically ill older adults admitted to the intensive care unit (ICU) are at a higher risk to develop delirium, which predisposes them to longer lengths of ICU and hospital stay, increased in-patient mortality, and higher risk of…
- Conditions
- Intensive Care Unit Delirium, Pain, Anxiety, Intensive Care Acquired Cognitive Impairment
- Trial name
- DDM (NCT04182334)
- Testing
- Slow Tempo Music, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Indiana University
Blood Pressure, Surgery
Comparison of Non-invasive and Invasive Blood Pressure Monitors
To compare a noninvasive and continuous radial artery blood pressure measurements utilizing ViTrack (developed by Dynocardia) to the standard of care radial artery catheterization, in patients undergoing surgery or those who are…
- Conditions
- Blood Pressure, Surgery, Intensive Care Unit
- Trial name
- NCT04506775
- Testing
- ViTrack, Radial artery catheterization
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Massachusetts, Worcester
Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia
Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery
Research indicates that hypothyroidism decreases heart contractility, reduces stroke volume and rate, affects the vascular endothelium, and increases the risk of atherosclerosis, systemic vascular resistance, hypertension…
- Conditions
- Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia, Euthyroid Sick Syndrome, Cardiac Surgery Requiring Cardiopulmonary Bypass
- Trial name
- L-Thyroxine (NCT06660823)
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Acute Respiratory Failure, Post-Intensive Care Syndrome
Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors
The m-CCRP randomized controlled trial will evaluate the efficacy of a collaborative critical care recovery program from acute respiratory failure (ARF) survivors in accomplishing the Institute of Healthcare Improvement's triple…
- Trial name
- m-CCRP (NCT03053245)
- Testing
- Mobile Critical Care Program, Attention Control
- Where
- 3 sites in United States
- Volunteers
- 503 people
- Sponsor
- Indiana University
Critically Ill, Post Intensive Care Syndrome
Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients
Objective: Test the ability of vibration to produce physiologic, biochemical, and anatomic changes consistent with exercise that would help prevent the development of muscle weakness that occurs when patients are immobile for…
- Trial name
- NCT03479008
- Testing
- Therapeutic Vibration Device
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Intensive Care Unit Syndrome
Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU
Despite the known benefits of geriatric care models among hospitalized older adults outside the intensive care unit (ICU), few studies have addressed the needs of older adults in the ICU; for example, sensory impairment…
- Trial name
- ACE-ICU (NCT04652453)
- Testing
- Geriatrics Bundle
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Yale University
Family Members, Post Intensive Care Unit Syndrome
Psychological Symptoms and Families of COVID-19 Patients
Families of patients in Intensive Care Units (ICUs) are at increased risk for developing psychological symptoms that can last for months after the patient is discharged.
- Conditions
- Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
- Trial name
- NCT04501445
- Testing
- Written Summary of Rounds
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Rush University Medical Center
Intensive Care (ICU) Myopathy
Neurosciences-Intensive Care Unit Electrical Stimulation
Patients admitted to the Neurosciences Intensive Care Unit (NSICU) are at particular risk of developing ICU-associated weakness and myopathy, given the unique risks of early mobilization in these patients, which include increased…
- Trial name
- NCT03547687
- Testing
- Electrical Stimulation Treatment, Neuromuscular Electrical Stimulation Treatment
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Oregon Health and Science University
Intensive Care Unit Survivors, Informal Caregivers (Family and Friends)
Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Patients who receive life support in intensive care units commonly suffer from persistent depression, anxiety, and post-traumatic stress disorder (PTSD) symptoms after discharge.
- Trial name
- NCT01983254
- Testing
- coping skills training, education program
- Where
- 4 sites in United States
- Volunteers
- 417 people
- Sponsor
- Duke University
Intensive Care Unit Syndrome, Intensive Care Neurological Disorder
Vanderbilt ICU Recovery Program Pilot Trial
Every year, millions of Americans are admitted to the intensive care unit. Due to advances in critical care, mortality rates are decreasing, increasing the number of ICU survivors.
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neurological Disorder, Intensive Care (ICU) Myopathy, Intensive Care Psychiatric Disorder (Diagnosis)
- Trial name
- VIP (NCT03124342)
- Testing
- VANDERBILT ICU RECOVERY PROGRAM
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Vanderbilt University Medical Center
Intensive Care Unit, Muscle Weakness
Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness
The purpose of this study is to investigate whether neuromuscular electrostimulation (NMES) will decrease ICU-associated weakness.
- Trial name
- NMES (NCT00709124)
- Testing
- Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Respiratory Disorders, Intensive Care, Neonatal
Timing of Planned Caesarean Section and Morbidity of the Newborn
The caesarean section rate is rising globally. About 10% of the newborns are submitted to a neonatal department after planned caesarean section, primarily with respiratory disorders.
- Trial name
- NCT00835003
- Testing
- Elective caesarean section
- Where
- 7 sites in Denmark
- Volunteers
- 1,273 people
- Sponsor
- Aarhus University Hospital