Clinical trials: Insomnia Chronic
Chronic Back Pain, Chronic Pain
Active Coping: Interdisciplinary Program for Chronic Pain, Physiotherapy Unit (Spain)
The goal of this observational intervention study is to evaluate the impact of a multidisciplinary active coping program for chronic back pain in adults referred from Primary Care to the Physiotherapy Unit of Teruel Ensanche.
- Conditions
- Chronic Back Pain, Chronic Pain, Back Pain, Low Back Pain, Chronic
- Trial name
- NCT07504094
- Testing
- Pain Neuroscience Education (PNE), Healthy Habits and Psychological Intervention, Therapeutic Exercise
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Insomnia Chronic
Prospective Observational Study on the Effectiveness of Daridorexant in Chronic Insomnia in a Real-World Setting
The primary objectives of this study is to evaluate the real-world effectiveness of daridorexant 50 mg in improving both subjective (self-report) and objective (actigraphic) sleep parameters in patients with chronic insomnia.
- Trial name
- NCT07132086
- Testing
- Daridorexant 50 mg orally, once daily at bedtime, administered as monotherapy or add-on therapy for chronic insomnia, in a real-world, observational, prospective clinical setting
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Insomnia Chronic, Fecal Microbiota Transplantation
The Efficacy and Safty of FMT in Patients With CID
This clinical trial aims to learn about the efficacy of fecal microbiota transplantation in patients with chronic insomnia disorder.
- Conditions
- Insomnia Chronic, Fecal Microbiota Transplantation, Sleep Disorder, Depression
- Trial name
- NCT05917379
- Testing
- fecal microbiota, synbiotics
- Where
- 7 sites in China
- Volunteers
- 80 people
- Sponsor
- Peking University Sixth Hospital
Fatigue Syndrome, Chronic
The Effect of a Self-Management Program in University Students
This study will be conducted as a randomized controlled pre-post test trial designed in accordance with the CONSORT guidelines. University students with chronic fatigue will be invited to participate; eligible participants will…
- Trial name
- NCT07455123
- Testing
- Self-Management Programme for Chronic Fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Insomnia
Safety and Efficacy of Zolpidem in the Long-Term Treatment of Insomnia
The purpose of this study is to evaluate the safety and efficacy of sublingual zolpidem during the long-term treatment of insomnia.
- Trial name
- NCT05456152
- Testing
- Sublingual Tablet
- Where
- Brazil
- Volunteers
- 358 people
- Sponsor
- EMS
Insomnia Disorder
The Study of Mechanism of Chronic Insomnia Disorder Using Acupuncture Based on Changes of Brain GABA and fMRI
Insomnia disorder is one of the major neuropsychiatric diseases which received more attention in recent years. Disturbances in the amino acid neurotransmitter, gama-amino butyric acid (GABA) and hyperarousal of cortex are…
- Trial name
- NCT03237338
- Testing
- ture acupuncture
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Insomnia, Sleep Initiation and Maintenance Disorders
Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)
This study was conducted to investigate the efficacy of treatment with Org 50081 (Esmirtazapine) compared to placebo in elderly participants with chronic primary insomnia.
- Conditions
- Insomnia, Sleep Initiation and Maintenance Disorders, Mental Disorders, Dyssomnias
- Trial name
- NCT00561821
- Testing
- Esmirtazapine
- Volunteers
- 538 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Insomnia Disorder
Online Tai Chi Versus Digital CBT-I for Chronic Insomnia
This multicenter randomized controlled trial will compare online Tai Chi (OTC) with digital cognitive behavioral therapy for insomnia (dCBT-I) in adults with chronic insomnia disorder.
- Trial name
- NCT07853651
- Testing
- Online Tai Chi, Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 172 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Chronic Non-cancer Pain, Insomnia
Chronic Insomnia in Non-Cancer Pain Patients
Pain and sleep are closely linked physiological processes that support overall health and functioning. Increasing evidence shows a dynamic, bidirectional relationship: poor sleep increases pain sensitivity, while chronic pain…
- Trial name
- PainSomnia (NCT07057232)
- Testing
- Usual care provided from pain specialist or within a dedicated pain unit
- Where
- 15 sites in Spain
- Volunteers
- 385 people
- Sponsor
- Germans Trias i Pujol Hospital
Intensive Sleep Retraining, Total Sleep Deprivation
Intensive Sleep Retraining and Total Sleep Deprivation for Treating Chronic Insomnia
The present study was designed to evaluate the efficacy of intensive sleep retraining for treating insomnia and explore its potential mechanisms of action.
- Conditions
- Intensive Sleep Retraining, Total Sleep Deprivation, Control Condition
- Trial name
- NCT06615336
- Testing
- Intensive Sleep retraining, Total Sleep Deprivation
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Autism Spectrum Disorder, Insomnia Chronic
Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism
Autism Spectrum Disorder (ASD) represents one of the most perplexing neurobiological disorders with a prevalence of 1 in 54 children.
- Conditions
- Autism Spectrum Disorder, Insomnia Chronic, Caregiver Burden
- Trial name
- NCT05373537
- Testing
- Cognitive behavioral therapy for Insomnia
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Insomnia Chronic, Dementia
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
Over the next 30 years, more than 10 million persons living with dementia in the United States will receive care at home from an unpaid and untrained family caregiver.
- Trial name
- NiteCAPP (NCT04632628)
- Testing
- Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Insomnia Chronic
Determination of Optimal Sleep Treatment Elements (The DOSE Project) - DISA
Insomnia is a widespread public health challenge considering its impact on daily life, comorbidity with other disorders, and socio-economic costs.
- Trial name
- DISA (NCT06781203)
- Testing
- Digitally delivered CBTI (eCBTI)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aarhus University Hospital
Insomnia Chronic, Anxiety
The Effects of Insomnia Treatment on Overnight Regulation of Emotional Memories and Risk for Mental Disorders
This project aims to elucidate whether CBCTi changes symptom severity or even remission of anxiety disorders as compared with a delayed-start control group.
- Trial name
- Restless (NCT06567210)
- Testing
- Immediate CBCTi, Delayed CBCTi
- Where
- Australia
- Volunteers
- 98 people
- Sponsor
- Woolcock Institute of Medical Research
Insomnia Chronic
STATE Trial: SusTained Attention Training to Enhance Sleep - Remote
This study is a validation study to document the acceptability of the Tonic and Phasic Alertness Training (TAPAT) program in older adults with chronic late-life insomnia.
- Trial name
- STATE (NCT03604380)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Active Comparator
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Posit Science Corporation
High School 11th Grade Students, Absence of Any Language, Hearing, Mental or Psychological Disability
The Effect of Motivational Support Program Applied to Adolescents on Sleep Quality and Academic Achievement
It was planned as a randomized controlled experimental study with a single-blind technique, pretest-posttest control group and repetitive measurements, in order to determine the effect of motivational support program applied to…
- Conditions
- High School 11th Grade Students, Absence of Any Language, Hearing, Mental or Psychological Disability, Turkish Speaking and Understanding, Having a PUKI Index Above 5ı
- Trial name
- NCT06004778
- Testing
- Motivational Support Program, Educational support
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Sleep Initiation and Maintenance Disorders
Efficacy and Safety of Zolpidem-MR Administered Over a Long Term Period as Needed for Insomnia (ZOLONG)
The primary objective of the study is to evaluate the hypnotic efficacy of zolpidem-MR 12.5 mg in comparison with placebo, when administered over a long-term period, on an "as needed" basis, in patients with chronic primary…
- Trial name
- NCT00425243
- Testing
- zolpidem-MR (SL800750)
- Where
- United States
- Volunteers
- 1,025 people
- Sponsor
- Sanofi
Generalized Anxiety Disorder (GAD), Chronic Insomnia
Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study
This is an open-label pilot clinical trial to evaluate the effects of transcranial alternating current stimulation (tACS) in adults diagnosed with generalized anxiety disorder (GAD) and chronic primary insomnia.
- Trial name
- NewWaves (NCT07429578)
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Chronic Insomnia, Cancer
Impact of Homeopathy for Persistent Insomnia in Patients With Cancer
Persistent insomnia is highly prevalent complaint in cancer survivors, but is seldom satisfactorily addressed. The adaptation to cancer care of a validated, cost-effective intervention may offer a practicable solution.
- Trial name
- NCT02515006
- Testing
- Homeopathy Medicine
- Where
- 2 sites in India
- Volunteers
- 160 people
- Sponsor
- Adwin Life Care
Chronic Atrophic Gastritis (CAG)
Association of Sleep Quality With Pathologic Staging, Acupuncture Treatment in Patients With Chronic Atrophic Gastritis: a Cross-sectional Study
In order to inform clinical treatment decisions and maximize treatment outcomes, this observational study set out to examine the relationship between pathological severity and sleep quality in patients with CAG.
- Trial name
- NCT06912178
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yi Liang