Clinical trials: Insomnia
Insomnia, Sleep Health
Project Women's Insomnia Sleep Health Equity Study (WISHES)
The purpose of this study is to achieve health and healthcare equity by implementing an equity-focused, mindfulness-based sleep intervention to reduce stress and sleep deficiency-related cardiometabolic disease burden in Black…
- Conditions
- Insomnia, Sleep Health, Cardiometabolic Health
- Trial name
- Project WISHES (NCT06348082)
- Testing
- Mindfulness-based therapy for insomnia (MBTI)
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Yale University
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Insomnia
Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients
Insomnia is very common in cancer patients. When left untreated, insomnia can lead to numerous serious consequences (e.g., psychological disorders) for the individual and significant costs for society (e.g., increased medical…
- Trial name
- Stepped Care (NCT01864720)
- Testing
- Professionally-administered cognitive-behavioral therapy for insomnia (CBT-I), Web-based cognitive-behavioral therapy for insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 177 people
- Sponsor
- CHU de Quebec-Universite Laval
Blood Brain Barrier Defect, Sleep Deprivation
The Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer's Disease
The aim of our study is the analysis of sleep phases and quality as well as the detection of respiratory pauses in subjects with cognitive disorder.
- Conditions
- Blood Brain Barrier Defect, Sleep Deprivation, Sleep Apnea, Alzheimer Disease
- Trial name
- NCT04096261
- Testing
- Diagnostic Test
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Depression, Sleep Quality
Sleep to Activate Mood Promotion
The investigators are aiming to examine the acceptability and feasibility of a portable bright light therapy instrument to improve sleep disturbance in a preventive intervention for depression.
- Trial name
- STAMP (NCT02413294)
- Testing
- Re-Timer glasses
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Laughter Yoga, Hemodialysis Patients
Effects of Laughter Yoga on Hemodialysis Patients' Plasma-Beta Endorphin Levels, Pain Levels and Sleep Quality
This study aimed to assess the effectiveness of laughter yoga on HD patients' plasma beta endorphin levels, pain levels and sleep quality.
- Trial name
- NCT04175652
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Cognitive Deficits, Mild
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination
This randomized, double-blind, placebo-controlled trial will evaluate whether 12 weeks of supplementation with the probiotic Lactobacillus rhamnosus GG combined with colon-delivered riboflavin will improve cognitive performance…
- Trial name
- MENTOR (NCT07410052)
- Testing
- Experimental 1, Experimental 2
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Older Adults, Cognitive Impairment
Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive Impairment
Patients with cognitive decline are frequently comorbid with sleep disorders which may in turn aggravate cognitive decline. Sedative dose dexmedetomidine improved sleep quality but incresed bradycardia and hypotension; low dose…
- Conditions
- Older Adults, Cognitive Impairment, Sleep Disorders, Dexmedetomidine
- Trial name
- NCT07610343
- Testing
- Dexmedetomidine-esketamine combination
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Insomnia
WELT-REST: WELT Randomized Evaluation of Sleep Therapy
The goal of this clinical trial is to learn whether the SleepQ mobile app can help reduce insomnia symptoms in adults diagnosed with insomnia.
- Trial name
- WELT-REST (NCT07289217)
- Testing
- SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- WELT corp
Sleep Initiation and Maintenance Disorders
A Study of Lemborexant in Chinese Participants With Insomnia Disorder
The primary purpose of this study is to confirm using polysomnography (PSG) that lemborexant 10 milligram (mg) is superior to placebo on objective sleep onset as assessed by latency to persistent sleep (LPS) during the last 2…
- Trial name
- NCT04549168
- Testing
- Lemborexant
- Where
- 23 sites in China, Taiwan
- Volunteers
- 194 people
- Sponsor
- Eisai Co., Ltd.
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Quality of Life, Functional and Cognitive Outcomes in Patients With Metastatic Hormone-Sensitive Prostate Cancer
This prospective observational study will evaluate quality of life, functional status, and cognitive outcomes in men with metastatic hormone-sensitive prostate cancer (mHSPC) receiving androgen receptor pathway inhibitors (ARPIs)…
- Trial name
- PRO-MIND (NCT07181122)
- Testing
- Androgen Receptor Pathway Inhibitors (ARPIs)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Ankara Etlik City Hospital
Cough, Sleep
The Effect of Honey on Nocturnal Cough and Sleep Quality
Cough is a common symptom in pediatric practice. It can be particularly troubling to children and their parents.It often results in discomfort to the child and loss of sleep to both the child and the parent.
- Trial name
- NCT01575821
- Testing
- Eucalyptus honey, Labiatae honey, Citrus honey
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Meir Medical Center
Insomnia, Schizophrenia
Insomnia in the Patient With Schizophrenic Disorder: Evaluation of a CBT and Psychoeducational Intervention
The study aims to evaluate the efficacy of a cognitive behavioural and psychoeducational intervention in patients with insomnia and diagnosed with a schizophrenic disorder.
- Trial name
- NCT05115604
- Testing
- cognitive behavioural intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- David Batalla-Martin
Adolescent Idiopathic Scoliosis
Assessment of Respiratory Parameters, Aerobic Capacity and Sleep Quality in Thoracic AIS
This study aims to compare respiratory parameters -including pulmonary function and respiratory muscle strength-as well as aerobic capacity and sleep quality in individuals with thoracic adolescent idiopathic scoliosis.
- Trial name
- NCT07187271
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Patients Diagnosed With Fibromyalgia Syndrome
The Effect of Pranayama Breathıng Exercıses on Paın, Anxıety,aAnd Sleep Qualıty in Indıvıduals wıth Fıbromyalgıa
Individuals diagnosed with fibromyalgia syndrome have a low quality of life due to factors such as pain, sleep problems, high anxiety, depression and low self-esteem, difficulty performing daily living activities, and inhibited…
- Trial name
- Pranayama (NCT07328763)
- Testing
- Pranayama breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ondokuz Mayıs University
Insomnia
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Neu-P11 in Subjects With Primary Insomnia
The primary objective of the study is to evaluate the safety and tolerability of Neu-P11, following the administration of multiple ascending oral doses (2, 5, 20, 50 mg or matching placebo) given nightly over 2 periods of 5 days…
- Trial name
- NCT01114126
- Testing
- Neu-P11
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Neuropathic Pain, Insomnia
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
The goal of this clinical study is to study sleep and its microstructure in neuropathic pain patients who have or who do not have a clinically significant sleep disturbance, before and during (after 1-month stabile dosage)…
- Conditions
- Neuropathic Pain, Insomnia, Sleep Disorder
- Trial name
- NCT06155916
- Testing
- Pregabalin
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Insomnia
A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.
The purpose of this study is to determine whether a handheld computer is superior to a self-help manual for the treatment of chronic primary insomnia.
- Trial name
- NCT00310284
- Testing
- Computerized delivery of cognitive-behavioral treatment of insomnia, Self-help manual to improve insomnia symptoms
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- PICS, Inc.
Insomnia, Major Depressive Disorder
Efficacy and Safety of Daridorexant in Patients With Major Depressive Disorder and Insomnia
The goal of this clinical trial is to evaluate the efficacy and safety of Daridorexant in major depressive disorder (MDD) patients with comorbid insomnia. The main questions to answer are: 1.
- Trial name
- NCT07555743
- Testing
- Daridorexant 50 mg
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge