Clinical trials: Inner Ear Disease
Vestibular Disorder, Bilateral Vestibulopathy
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
This study has three main goals (1) to explore the effects of electrical stimulations of the peripheral vestibular system(2) to assess the potential of this technique to rehabilitate basic vestibular functions in patients with…
- Conditions
- Vestibular Disorder, Bilateral Vestibulopathy, Bilateral Vestibular Loss
- Trial name
- NCT05246553
- Testing
- Electrical stimulation of the vestibular system, Electrical stimulation of the auditory system, Bilateral vestibulopathy Patients (BV)
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nils Guinand
Ototoxicity
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
The primary objective of this study is to determine the safety and efficacy of SPI-1005 treatment in CF patients with active pulmonary exacerbation that are receiving an IV course of tobramycin, determined by comparing hearing…
- Trial name
- NCT02819856
- Testing
- SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Meniere's Disease
OTO-104 for Meniere's Disease
The purpose of this study is to evaluate the safety of OTO-104 in subjects with unilateral Meniere's disease. The effectiveness of OTO-104 to reduce the symptoms of Meniere's disease will also be evaluated.
- Trial name
- NCT01084525
- Testing
- OTO-104 (steroid) 3 mg, OTO-104 (steroid) 12 mg
- Where
- 15 sites in United States
- Volunteers
- 44 people
- Sponsor
- Otonomy, Inc.
Unilateral Peripheral Vestibular Hypofunction, Vestibular Disorders
Ai Chi-Based Rehabilitation for Peripheral Unilateral Vestibular Dysfunction
This study aims to evaluate the effects of an Ai Chi-based rehabilitation program on balance, dizziness severity, and quality of life in patients with unilateral peripheral vestibular hypofunction.
- Conditions
- Unilateral Peripheral Vestibular Hypofunction, Vestibular Disorders, Dizziness, Vertigo Benign Positional
- Trial name
- AICHI-VR (NCT07559162)
- Testing
- Ai Chi-based exercise program, Home-Based Vestibular Rehabilitation
- Volunteers
- 38 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Children, Only, Vestibular Disorder
Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing Loss
The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function, Sensorineural Hearing Loss
- Trial name
- VASIC (NCT06229717)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Gødstrup Hospital
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Vestibular Disease
Vibrotactile Feedback During Vestibular Therapy
This study evaluates the use of vibrotactile feedback to traditional vestibular treatment protocols. Half the patients will have vibrotactile feedback added to their treatment protocols while the other half will undergo…
- Trial name
- NCT02867683
- Testing
- Vibrotactile Feedback
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Vertigo, Peripheral
Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo
This is prospective, randomised double-blind study that will be conducted in the emergency department of 3 university hospitals (FB Monastir, Sahloul Sousse, and FH Sousse) to compare the efficacy of two doses of diazepam…
- Trial name
- Vertigo (NCT06293989)
- Testing
- Diazepam 5mg, Diazepam 10 mg
- Volunteers
- 1,000 people
- Sponsor
- University of Monastir
Sleep Quality, Vital Signs
The Effect of Eye Masks and Earplugs In Intensive Care Unit Patients
This study was planned as a randomized controlled and experimental study to evaluate the effect of eye masks and earplugs on sleep quality and vital signs in intensive care patients.
- Trial name
- NCT05970614
- Testing
- Eye masks and ear plugs
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Osmaniye Korkut Ata University
Vestibular Diseases, Disturbance; Balance, Labyrinth
The Efficacy of Balance Gaming as an Adjunct to Vestibular Rehabilitation Therapy
Patients with a unilateral vestibular loss often complain of dizziness and imbalance. Movement usually increases these symptoms often resulting in patients avoiding these movements, causing further limitations in their activities…
- Trial name
- NCT01305278
- Testing
- Use of Nintendo Wii Balance Gaming system
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Old Age, Vestibular Disorder
Comparative Effects of Virtual Reality and Vestibular Exercises on Balance Gait in Older Adults
To compare the effects of virtual reality and vestibular exercises on balance, gait, and activities of daily living in older adults.
- Conditions
- Old Age, Vestibular Disorder, Balance, Exercise
- Trial name
- NCT06407726
- Testing
- virtual reality training group, vestibular exercise group
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vestibular Disorder, Mild Traumatic Brain Injury
Randomized Controlled Trial for Vestibular Treatment in Concussion
A prospective, single-blind, four-group multi-center randomized controlled trial (RCT) of targeted rehabilitation exercises for vestibular symptoms and impairments (T-REV) in civilians with mild traumatic brain injury (mTBI) will…
- Trial name
- NCT03600324
- Testing
- T-REV
- Where
- 4 sites in United States
- Volunteers
- 121 people
- Sponsor
- University of Pittsburgh
Vertigo
Treatments for Benign Paroxysmal Positional Vertigo (BPPV)
The purpose of this study was to determine the relative short- and long-term efficacy of several physical treatment paradigms commonly employed for the treatment of benign paroxysmal positional vertigo (BPPV), including the…
- Trial name
- NCT00000359
- Testing
- Canalith repositioning maneuver (Epley maneuver), Semont maneuver, Brandt-Daroff exercises
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Baylor College of Medicine
Vestibular Disorder
Activity Treatment on Vestibular Rehabilitation
In this study it was aimed to investigate the effects of home treatment program based standard activity on dizziness, balance and daily life activity in patients with dizziness complaint originated from chronic unilateral…
- Trial name
- NCT04425928
- Testing
- occupational therapy based activity training programs, Physiotherapy based exercise training programs
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Bilgehan Tekin Dal
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Vertigo, Paroxysmal
Comparison of Half-Somersault Exercise With Brandt-Daroff Exercise in BPPV.
This study is important as there are numbers of BPPV patients presenting to outpatient departments which needs more efficient techniques for management of BPPV.
- Trial name
- NCT04469309
- Testing
- Group I Brandt-Daroff Exercises, Group II Half-Somersault Maneuver
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Stroke, Vertigo
Telemedical Examination of a Three-Component Oculomotor Testing Battery
The study investigates the feasibility and safety of the telemedical implementation of three diagnostic oculomotor tests using a video-oculography device and an extended teleconferencing system.
- Conditions
- Stroke, Vertigo, Dizziness
- Trial name
- NCT02938221
- Testing
- Telemedical video-oculography system
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Munich Municipal Hospital
Persistent Postural-perceptual Dizziness
Prevalence and Diagnosis of Persistent Postural-perceptual Dizziness
Persistent Postural-Perceptual Dizziness (PPPD) is a chronic vestibular disorder characterized by persistent symptoms of dizziness or unsteadiness that lasts for three months or longer.
- Trial name
- NCT07855081
- Testing
- Comprehensive Audio-Vestibular Evaluation
- Volunteers
- 50 people
- Sponsor
- Sohag University
Colorectal Cancer, Oncologic Complications
The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
The goal of this clinical trial is to learn about the cause of dizziness and decline in walking ability in in older adults ≥65 years during chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Oncologic Complications, Comprehensive Geriatric Assessment, Vestibular Rehabilitation
- Trial name
- SaVe (NCT05710809)
- Testing
- Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet