Clinical trials: Injuries
Rib Fracture, Rib Fracture Multiple
Zimmer Biomet-RibFix Titan
Prospective, single-center, non-randomized, single-cohort, post-market clinical follow-up study to confirm the safety, performance, and clinical benefits for the use of the RibFix Titan™ system implants and instrumentation) in…
- Trial name
- NCT07485829
- Testing
- The RibFix Titan™ device should be used within this arm of the study.
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Zimmer Biomet
Shoulder Pain, Rotator Cuff Injuries
Exercise Program in Patients With Shoulder Pain and Rotator Cuff Tear
Introduction: Atraumatic and degenerative rotator cuff tears are common in individuals over 55 years of age. This condition can have a high impact on social life and is associated with chronic pain, weakness and dysfunction of…
- Conditions
- Shoulder Pain, Rotator Cuff Injuries, Rehabilitation
- Trial name
- NCT03962231
- Testing
- Rotator Cuff Unloading Exercise Program, Rotator Cuff Loading Exercise Program
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Larissa Pechincha Ribeiro
Major Depressive Disorder, Post-Traumatic Stress Disorder
Imaging SV2A in Mood Disorders
This study is designed to examine SV2A density in MDD and PTSD as a correlate of synaptic density, and to determine whether ketamine administration will reverse the synaptic loss in vivo in human subjects.
- Trial name
- NCT02734602
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Circulatory Shock, Hemodynamic Instability
Peripheral pULSe Assessment and Arterial pRessure (PULSAR)
This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending…
- Conditions
- Circulatory Shock, Hemodynamic Instability, Hypotension, Shock
- Trial name
- PULSAR (NCT07609095)
- Testing
- Peripheral Pulse Palpation
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Region Stockholm
Concussion Post Syndrome
The Effect of Binasal Occlusion on Balance Following a Concussion
This study evaluates the effect of binasal occlusion (BNO) glasses on balance and eye movement in adults with dizziness after a concussion.
- Trial name
- NCT03355339
- Testing
- Binasal occlusion, No binasal occlusion
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Posttraumatic Stress Disorder
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
The purpose of this study is to assess the safety and effectiveness of co-administered MDMA and psilocybin in military Veterans with a diagnosis of Posttraumatic Stress Disorder (PTSD).
- Trial name
- PAM-VET (NCT06989957)
- Testing
- Psilocybin, MDMA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Pulmonary Disease
Inhaled Nitric Oxide to Prevent and Treat Bronchopulmonary Dysplasia
Inhaled nitric oxide in preterm babies with respiratory failure or ventilator dependence will: 1. decrease the incidence of Bronchopulmonary Dysplasia (BPD) or death 2.
- Trial name
- NO-BPD (NCT01503801)
- Testing
- Nitric Oxide, respiratory support
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fudan University
Aging, Athletic Injuries
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability.
- Conditions
- Aging, Athletic Injuries, Physical Inactivity, Knee Injuries and Disorders
- Trial name
- NCT05344001
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marquette University
Pain, Acute, Laceration
Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department
The purpose of this study is to determine if topical analgesia using a lidocaine and prilocaine cream improves pain scores compared to the usual local anesthesia using subcutaneous 1% lidocaine and adrenalin injected near the…
- Trial name
- NCT03071601
- Testing
- Lidocaine-Prilocaine Cream 2.5-2.5%, Lidocaine 1% Epinephrine 0.005mg/mL solution
- Where
- 2 sites in France
- Volunteers
- 132 people
- Sponsor
- Centre Hospitalier le Mans
Carpal Tunnel Syndrome (CTS)
Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients
The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.
- Trial name
- NCT06686212
- Testing
- Sensory re-education+ strengthening exercises+ kinesio taping, Neural mobilization+ Strengthening exercises+ Kinesio taping.
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Acute Kidney Injury
Renal Replacement Therapy Plus Extracorporeal Carbon Dioxide Removal
This study aims to assess whether in patients with acute kidney injury (AKI) requiring mechanical ventilation, a strategy that combines renal replacement therapy (RRT) and extracorporeal carbon dioxide removal (ECCO2R) allows…
- Trial name
- NCT02595619
- Testing
- RRT plus ECCO2R
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Turin, Italy
Cardiac Amyloidosis, Cardiac Disease
High Resolution Three-dimensional Maps of the Right Chambers in Patient Diagnosed With Cardiac Amyloidosis
Amyloid heart disease is an accumulation of fibrillar proteins in the extracellular sector of the heart. Identified on echocardiography as Ventricular hypertrophy.
- Trial name
- CARTO-AMYLO (NCT04956965)
- Testing
- Cardiac electro-mapping
- Where
- Martinique
- Volunteers
- 24 people
- Sponsor
- University Hospital Center of Martinique
Hip Injuries, Acetabular Labral Tear
A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement
This study aims to address hip labral tears and compare arthroscopic labral repair versus debridement in non-athletic population aged 20 to 50 years old, including both sexes.
- Conditions
- Hip Injuries, Acetabular Labral Tear, Femoro Acetabular Impingement
- Trial name
- NCT06288867
- Testing
- Arthroscopic Labral Repair, Arthroscopic Labral Debridement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Autism, Trauma
A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults
The goal of this single-group clinical trial is to learn about the initial efficacy and feasibility of telehealth-delivered Written Exposure Therapy (WET) for autistic adults with traumatic stress symptoms.
- Conditions
- Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
- Trial name
- NCT05862467
- Testing
- Written Exposure Therapy (WET) via telehealth
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wyoming
Skin Injury
Thermotape High-adhesion Medical Tape Comparison Study
This objective of this study is to compare the safety and performance of Thermotape compared to Tegaderm™ tape and Kind™ tape over the course of 24 hours.
- Trial name
- NCT05449600
- Testing
- Thermotape, Tegaderm, Kind
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hamstring Injury, Muscle Rupture
Effect of NMES+ on Hamstring Lesion (3a/3b)
The goal of this clinical trial is to analyze the effect of the electrical stimulation superimposed onto movement in healthy semi-professional athletes who sustained a type 3a/3b hamstring strain injury.
- Conditions
- Hamstring Injury, Muscle Rupture, Hamstring Sprain
- Trial name
- NCT05786300
- Testing
- NMES+, Rehab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Myocardial Injury, Myocarditis
Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study)
The study will focus on cardiac blood and imaging biomarkers to facilitate early recognition of patients at risk for myocardial injury after COVID-19 vaccination.
- Conditions
- Myocardial Injury, Myocarditis, COVID-19 Vaccination, SARS-CoV-2
- Trial name
- MYOVAX (NCT04967807)
- Testing
- Cardiac PET/MRI, Blood Biomarkers
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Lumbar; Injury
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal Surgery
Spinal surgeries are generally associated with intense pain in the postoperative period, especially for the initial few days. The aim of this study is to examine the effect of intraoperative intravenous acetaminophen in spine…
- Trial name
- NCT05764707
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Carpal Tunnel Syndrome Treatment
Effectiveness of Corticosteroid and 5% Dextrose Versus USG-guided Ozone Injections in Patients With Carpal Tunnel Syndrome: Three Blind Randomized Studies
Effectiveness of corticosteroid and 5% dextrose versus USG-guided ozone injections in patients with carpal tunnel syndrome: Three blind randomized studies
- Trial name
- NCT07002892
- Testing
- Ozon treatment, Steroid treatment, Dextrose 5%
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Yunus Burak Bayır
Cardiovascular Surgical Procedures, Arthroplasty, Replacement
Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
The specific aims are to determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies across a heterogeneous sample of hospitals…
- Conditions
- Cardiovascular Surgical Procedures, Arthroplasty, Replacement, Hysterectomy
- Trial name
- NCT00114036
- Testing
- Quality improvement strategies
- Where
- 3 sites in United States
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)