Clinical trials: Inhalation; Gas
Respiratory Failure
PEEP Influence on Gas Exchange During Early Weaning
The purpose of this study is to determine the differences in oxygenation and decarboxylation between two weaning processes.
- Trial name
- MHOPEEP (NCT02281695)
- Testing
- PEEP adjusment during the Weaning process
- Where
- Germany
- Sponsor
- Marienhospital Osnabrück
Mediastinal Mass Requiring Video-assisted Surgical Excision
Effect of End-inspiratory Pause on Gas Exchange During Mediastinal Mass Excision With CO2 Insufflation and One-lung Ventilation
" Mediastinal mass excision is typically performed via video-assisted thoracoscopic surgery (VATS). To secure a clear surgical field, the ipsilateral lung must be deflated, achieved through one-lung ventilation (OLV) and…
- Trial name
- NCT06956079
- Testing
- EIP-first, EIP-later
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Avalanche Burial
Impact of CO2 Absorption on Gas Exchange and Ventilation Patterns While Breathing Into a Snow Air Pocket
Asphyxia is by far the most common cause of death after critical avalanche burial. The presence of an air pocket increases the survival chances, but expired air rich in carbon dioxide (CO2) progressively displaces oxygen (O2) in…
- Trial name
- AVACO2R (NCT06895759)
- Testing
- Soda lime
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Hearing Loss, Sensorineural
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Sudden Sensorineural Hearing Loss
Idiopathic sudden sensorineural hearing loss (ISSHL) is defined according to American Academy of Otolaryngology as a hearing loss of at least 30 decibel over 3 contiguous test frequencies occurring within a 72h period.
- Trial name
- NCT04881435
- Testing
- Hydrogen gas therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Post Coronary Artery Bypass Grafting
Effectiveness of Incentive Spirometer and Diaphragmatic Breathing Exercise on ABG Measures in Post-CABG Patients
The rate of pulmonary complications following Coronary artery bypass graft (CABG) is high. Early pulmonary exercises are important in preventing this complication following cardiac surgery.
- Trial name
- NCT05684679
- Testing
- Incentive spirometer plus Chest physiotherapy, Diaphragmatic breathing exercise plus Chest physiotherapy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Autoimmune Pulmonary Alveolar Proteinosis
Inhaled GM-CSF Therapy of Autoimmune PAP
This is a prospective, randomized, open-label, long-term, phase 2 study of inhaled granulocyte/macrophage-colony stimulating factor following whole lung lavage therapy in patients with autoimmune pulmonary alveolar proteinosis.
- Trial name
- NCT00901511
- Testing
- Baseline WLL, Sargramostim, Rescue WLL
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Aneurysmal Subarachnoid Hemorrhage
Early Hydrogen-Oxygen Gas Mixture Inhalation in Patients With Aneurysmal Subarachnoid Hemorrhage (HOMA)
This was a randomized, single-center trial. On the basis of standard-of-care, patients in the treatment group inhaled H2-O2 (66% hydrogen; 33% oxygen) at 3 L/min via nasal cannula by using the Hydrogen/Oxygen Generator (model…
- Trial name
- HOMA (NCT05282836)
- Testing
- Hydrogen Oxygen Generator with Nebulizer
- Volunteers
- 206 people
- Sponsor
- Beijing Tiantan Hospital
High Altitude, Inhalation; Gas
Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude
High altitude (>2400 m) is associated with decreased atmosphere pressure leading to hypoxia which in turn impairs exercise capacity and causes acute mountain sickness (AMS).
- Conditions
- High Altitude, Inhalation; Gas, Acute Mountain Sickness
- Trial name
- NCT05798416
- Testing
- Exercise under inhalation CO2, Exercise under inhalation ambient air
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Covid19, Hydrogen-oxygen Gas
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19)
This study is a multicenter, randomized, open, parallel-controlled study. Qualified subjects will randomly be assigned to the experimental arm or the control arm according to the ratio of 1:1, with age (> 60 years or ≤ 60 years)…
- Conditions
- Covid19, Hydrogen-oxygen Gas, AMS-H-03
- Trial name
- NCT04594460
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, OLO-1 Medical Molecular Sieve Oxygen Generator
- Where
- 2 sites in China
- Volunteers
- 198 people
- Sponsor
- Guangzhou Institute of Respiratory Disease