Clinical trials: Inguinal Hernia Unilateral
Inguinal Hernia
Ultrasound-guided Ilioinguinal-iliohypogastric Block for Inguinal Hernia Repair
Aim: To investigate whether ultrasound-guided perineural administration of 20 ml bupivacaine 5 mg/ml vs 20 ml isotonic saline at the ilioinguinal-iliohypogastric nerves have a clinically analgesic effect after unilateral open…
- Trial name
- NCT01326039
- Testing
- bupivacaine, saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Analgesia, Epidural
TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia
Caudal epidural block is a well-established and commonly performed regional neuraxial technique for providing intraoperative and postoperative analgesia in children scheduled for lower abdomen/perineal surgical interventions.
- Trial name
- NCT03482947
- Testing
- ultrasonography-guided TAP block, Caudal epidural block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Pain Management, Mtapa Block
M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery
Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room.
- Conditions
- Pain Management, Mtapa Block, TAP Block
- Trial name
- pain (NCT07311902)
- Testing
- TAP Block Group, M TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Sedation During Spinal Anesthesia
Sedation During Spinal Anesthesia
Patients during spinal anesthesia should be sedated.
- Trial name
- NCT03133780
- Testing
- Ketamine, Midazolam
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Pain, Hernia
Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy
This is a prospective, randomized, double-blinded, and placebo-controlled trial comparing oxycodone/acetaminophen prescribed with or without ibuprofen for pain control following open unilateral inguinal hernia repair, with…
- Trial name
- NCT02929589
- Testing
- Ibuprofen, Opioid Medication, Ibuprofen + Opioid medication
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mike O'Callaghan Military Hospital
Inguinal Hernia Unilateral, Inguinal Hernia Bilateral
Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males
This is a prospective, single-center, two-arm Phase 1 safety and feasibility trial evaluating anti-estrogen therapy in men age 50 years and older with symptomatic unilateral inguinal hernias.
- Conditions
- Inguinal Hernia Unilateral, Inguinal Hernia Bilateral, Inguinal Hernia Without Obstruction or Gangrene, Inguinal Hernia, Without Mention of Obstruction or Gangrene
- Trial name
- RIGHT (NCT07604272)
- Testing
- Fulvestrant, Anastrozole (ARIMIDEX™)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Unilateral Simple Inguinal Hernia
Mesh Position and Outcomes Following Inguinal Hernia Repair Using an MRI Visible Hernia Mesh
Inguinal hernia repair can be considered as one of the most frequent surgeries in general surgery worldwide. Surgical hernia repair procedures can generally be divided into minimally invasive (TEP, TAPP) and open techniques (e.g.
- Trial name
- NCT02770703
- Testing
- DynaMesh visible mesh
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Inguinal Hernia, Inguinal Hernia, Indirect
Laryngeal Mask Airway in Laparoscopic Hernia Repair
This prospective randomized study will evaluate the effectiveness of laryngeal mask airway (LMA) versus endotracheal intubation (ETT) for patients undergoing laparoscopic inguinal hernia at CMH.
- Conditions
- Inguinal Hernia, Inguinal Hernia, Indirect, Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
- Trial name
- NCT06023394
- Testing
- Laryngeal Mask Airway, Endotracheal Tube Device
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Mercy Hospital Kansas City
Inguinal Hernia,Quadratus Lumborum Block , Unilateral Intrathecal Block
Qudratus Lumborum Block Versus Unilateral Intrathecal Block for Inguinal Hernia Repair
compare between Quadratus lumborum block and unilateral intrathecal block for patients undergoing inguinal hernia repair regarding the quality of anesthesia and hemodynamic stability of patients.
- Trial name
- NCT04805580
- Testing
- unilateral intrathecal block
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Postoperative
Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries
This study will evaluate the efficacy and safety of intrathecal non-preservative-free morphine and its effect on pain in patients undergoing unilateral inguinal hernia surgeries.
- Trial name
- NCT06319859
- Testing
- Morphine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Inguinal Hernia
A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants
The primary purpose of the GAS study is to determine whether different types of anesthesia (Regional versus General) given to 720 infants undergoing inguinal hernia repair results in equivalent neurodevelopmental outcomes.
- Trial name
- GAS (NCT00756600)
- Testing
- Regional Anesthesia, General Anesthesia
- Where
- 30 sites in United States, Australia and 5 more
- Volunteers
- 643 people
- Sponsor
- Boston Children's Hospital
To Compare ILI/IHG Block to Wound Infiltration for Pain Relief After Hernia Repair
To Compare Ilioinguinal/Iliohypogastric Block to Wound Infiltration for Pain Relief After Hernia Repair in Adults
This study was conducted to assess the postoperative painscores in patients undergoing open inguinal hernia repair between two groups receiving either U/S guided ilioinguinal/iliohypogastric nerves block with Ropivacaine or wound…
- Trial name
- NCT04462510
- Testing
- Block/Local infiltration
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Hernia, Inguinal
Impacts of Stoppa and Total Extraperitoneal Inguinal Hernia Repair on the Lower Extremity Muscular Functions
Comparison of physical activity parameters of the lower extremity muscles in patients who received total extraperitoneal repair (TEP) and STOPPA repair.
- Trial name
- NCT02813057
- Testing
- Stoppa inguinal hernia repair, Total extraperitoneal inguinal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Akdeniz University
Unilateral Inguinal Hernia
Evaluation of Mesh Integration and Mesh Contraction After Open Preperitoneal Inguinal Hernia Repair Using a Memory Ring Containing Device
The aim of this study is to evaluate whether preperitoneal mesh placement using a nitinol containing large pore polypropylene mesh (REBOUND HRD™) offers a satisfying patient recovery, quick reconvalescence and adequate tissue…
- Trial name
- REBOUND (NCT01622712)
- Testing
- Rebound HRD Mesh
- Where
- 2 sites in Belgium
- Volunteers
- 235 people
- Sponsor
- University Hospital, Ghent
Postoperative Pain
Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair
The purpose of this study is to evaluate three dose levels of SKY0402 compared with 105 mg of bupivacaine HCl.
- Trial name
- NCT00485433
- Testing
- Bupivacaine HCl, SKY0402
- Where
- 7 sites in United States
- Volunteers
- 98 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Unilateral Inguinal Hernia
Tizanidine and Pain After Herniorrhaphy
Herniorrhaphy is the most frequent general surgical procedure. There are moderate pain complaints after herniorrhaphy. Besides causing discomfort to the patients, pain, can delay recovery and discharge and cause cognitive…
- Trial name
- NCT02016443
- Testing
- Tizanidine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Diskapi Teaching and Research Hospital
Postoperative Pain, Inguinal Hernia Unilateral
The Comparison of the Transversalis Fascia Plane Block With Ilioinguinal/Iliohypogastric Nerve Block
This study compares the transversalis fascia plane block with the ilioinguinal/iliohypogastric nerve block in children undergoing hernia repair surgery.
- Conditions
- Postoperative Pain, Inguinal Hernia Unilateral, Children, Only
- Trial name
- NCT03520907
- Testing
- Transversalis Fascia Plane Block, Ilioinguinal/iliohypogastric Nerve Block
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Kazuhiko Okuyama, MD
Inguinal Hernia, Primary
The Outcome After Lichtenstein Operation vs. ProGrip Patch Repair of Inguinal Hernia
For the present study, 400 consecutive men with unilateral primary inguinal hernia are randomized to Lichtenstein repair using either light weight polypropylene mesh (38g/m2) or light weight ProGrip mesh.
- Conditions
- Inguinal Hernia, Primary, Unilateral
- Trial name
- NCT01026935
- Testing
- Open inguinal hernia repair
- Where
- 2 sites in Finland
- Volunteers
- 398 people
- Sponsor
- Helsinki University Central Hospital
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem